The RUNX1–PU.1 axis in the control of hematopoiesis von Imperato, Maria Rosaria, Cauchy, Pierre, Obier, Nadine, Bonifer, Constanze

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Chromatin priming of genes in development: concepts, mechanisms and consequences von Bonifer, Constanze, Cockerill, Peter N

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Standing at odds: mutated RAS and hematopoietic stem cells von Nafria, Monica, Bonifer, Constanze

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Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data von Piper, Jason, Elze, Markus C, Cauchy, Pierre, Cockerill, Peter N, Bonifer, Constanze, Ott, Sascha

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RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia von Grinev, Vasily V., Barneh, Farnaz, Ilyushonak, Ilya M., Nakjang, Sirintra, Smink, Job, van Oort, Anita, Clough, Richard, Seyani, Michael, McNeill, Hesta, Reza, Mojgan, Martinez-Soria, Natalia, Assi, Salam A., Ramanouskaya, Tatsiana V., Bonifer, Constanze, Heidenreich, Olaf

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Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation von Goode, Debbie K., Obier, Nadine, Vijayabaskar, M.S., Lie-A-Ling, Michael, Lilly, Andrew J., Hannah, Rebecca, Lichtinger, Monika, Batta, Kiran, Florkowska, Magdalena, Patel, Rahima, Challinor, Mairi, Wallace, Kirstie, Gilmour, Jane, Assi, Salam A., Cauchy, Pierre, Hoogenkamp, Maarten, Westhead, David R., Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold, Bonifer, Constanze

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RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks von Kellaway, Sophie G, Keane, Peter, Kennett, Ella, Bonifer, Constanze

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The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation von Martinez-Soria, Natalia, McKenzie, Lynsey, Draper, Julia, Ptasinska, Anetta, Issa, Hasan, Potluri, Sandeep, Blair, Helen J., Pickin, Anna, Isa, Asmida, Chin, Paulynn Suyin, Tirtakusuma, Ricky, Coleman, Daniel, Nakjang, Sirintra, Assi, Salam, Forster, Victoria, Reza, Mojgan, Law, Ed, Berry, Philip, Mueller, Dorothee, Osborne, Cameron, Elder, Alex, Bomken, Simon N., Pal, Deepali, Allan, James M., Veal, Gareth J., Cockerill, Peter N., Wichmann, Christian, Vormoor, Josef, Lacaud, Georges, Bonifer, Constanze, Heidenreich, Olaf

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Regulation of developmentally controlled enhancer activity by extrinsic signals in normal and malignant cells: AP-1 at the centre von Maytum, Alexander, Obier, Nadine, Cauchy, Pierre, Bonifer, Constanze

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Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones von de Boer, Bauke, Prick, Janine, Pruis, Maurien G., Keane, Peter, Imperato, Maria Rosaria, Jaques, Jennifer, Brouwers-Vos, Annet Z., Hogeling, Shanna M., Woolthuis, Carolien M., Nijk, Marije T., Diepstra, Arjan, Wandinger, Sebastian, Versele, Matthias, Attar, Ricardo M., Cockerill, Peter N., Huls, Gerwin, Vellenga, Edo, Mulder, André B., Bonifer, Constanze, Schuringa, Jan Jacob

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Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth von Kellaway, Sophie G., Potluri, Sandeep, Keane, Peter, Blair, Helen J., Ames, Luke, Worker, Alice, Chin, Paulynn S., Ptasinska, Anetta, Derevyanko, Polina K., Adamo, Assunta, Coleman, Daniel J. L., Khan, Naeem, Assi, Salam A., Krippner-Heidenreich, Anja, Raghavan, Manoj, Cockerill, Peter N., Heidenreich, Olaf, Bonifer, Constanze

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Expression of RUNX1-ETO Rapidly Alters the Chromatin Landscape and Growth of Early Human Myeloid Precursor Cells von Nafria, Monica, Keane, Peter, Ng, Elizabeth S., Stanley, Edouard G., Elefanty, Andrew G., Bonifer, Constanze

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Stepwise Activation of Enhancer and Promoter Regions of the B Cell Commitment Gene Pax5 in Early Lymphopoiesis von Decker, Thorsten, Pasca di Magliano, Marina, McManus, Shane, Sun, Qiong, Bonifer, Constanze, Tagoh, Hiromi, Busslinger, Meinrad

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RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence von Lie-A-Ling, Michael, Marinopoulou, Elli, Li, Yaoyong, Patel, Rahima, Stefanska, Monika, Bonifer, Constanze, Miller, Crispin, Kouskoff, Valerie, Lacaud, Georges

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Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate von Obier, Nadine, Cauchy, Pierre, Assi, Salam A, Gilmour, Jane, Lie-A-Ling, Michael, Lichtinger, Monika, Hoogenkamp, Maarten, Noailles, Laura, Cockerill, Peter N, Lacaud, Georges, Kouskoff, Valerie, Bonifer, Constanze

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Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma von Lamprecht, Björn, Walter, Korden, Kreher, Stephan, Kumar, Raman, Hummel, Michael, Lenze, Dido, Köchert, Karl, Bouhlel, Mohamed Amine, Richter, Julia, Soler, Eric, Stadhouders, Ralph, Jöhrens, Korinna, Wurster, Kathrin D, Callen, David F, Harte, Michael F, Giefing, Maciej, Barlow, Rachael, Stein, Harald, Anagnostopoulos, Ioannis, Janz, Martin, Cockerill, Peter N, Siebert, Reiner, Dörken, Bernd, Bonifer, Constanze, Mathas, Stephan

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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1 von Potluri, Sandeep, Assi, Salam A., Chin, Paulynn S., Coleman, Dan J.L., Pickin, Anna, Moriya, Shogo, Seki, Naohiko, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze

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Rewiring of the Transcription Factor Network in Acute Myeloid Leukemia von Assi, Salam A, Bonifer, Constanze, Cockerill, Peter N

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Macrophage development from HSCs requires PU.1-coordinated microRNA expression von Ghani, Saeed, Riemke, Pia, Schönheit, Jörg, Lenze, Dido, Stumm, Jürgen, Hoogenkamp, Maarten, Lagendijk, Anne, Heinz, Sven, Bonifer, Constanze, Bakkers, Jeroen, Abdelilah-Seyfried, Salim, Hummel, Michael, Rosenbauer, Frank

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Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell ly... von Davies, Nicholas, Francis, Tegan, Oldreive, Ceri, Azam, Maria, Wilson, Jordan, Byrd, Philip J, Burley, Megan, Sharma-Oates, Archana, Keane, Peter, Alatawi, Sael, Higgs, Martin R, Rudzki, Zbigniew, Ibrahim, Maha, Perry, Tracey, Agathanggelou, Angelo, Hewitt, Anne-Marie, Smith, Edward, Bonifer, Constanze, O'Connor, Mark, Forment, Josep V, Murray, Paul G, Fennell, Eanna, Kelly, Gemma, Chang, Catherine, Stewart, Grant S, Stankovic, Tatjana, Kwok, Marwan, Taylor, Alexander Malcolm

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