Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides von Grove, Tyler L, Himes, Paul M, Hwang, Sungwon, Yumerefendi, Hayretin, Bonanno, Jeffrey B, Kuhlman, Brian, Almo, Steven C, Bowers, Albert A

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Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1 von Lewis-Ballester, Ariel, Pham, Khoa N., Batabyal, Dipanwita, Karkashon, Shay, Bonanno, Jeffrey B., Poulos, Thomas L., Yeh, Syun-Ru

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Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex von Garrett-Thomson, Sarah C., Massimi, Aldo, Fedorov, Elena V., Bonanno, Jeffrey B., Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D., Love, James D., Garforth, Scott J., Guha, Chandan, Almo, Steven C.

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Anti–CTLA-4 therapy requires an Fc domain for efficacy von Ingram, Jessica R., Blomberg, Olga S., Rashidian, Mohammad, Ali, Lestat, Garforth, Scott, Fedorov, Elena, Fedorov, Alexander A., Bonanno, Jeffrey B., Le Gall, Camille, Crowley, Stephanie, Espinosa, Camilo, Biary, Tamara, Keliher, Edmund J., Weissleder, Ralph, Almo, Steven C., Dougan, Stephanie K., Ploegh, Hidde L., Dougan, Michael

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Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab von Ramagopal, Udupi A., Liu, Weifeng, Garrett-Thomson, Sarah C., Bonanno, Jeffrey B., Yan, Qingrong, Srinivasan, Mohan, Wong, Susan C., Bell, Alasdair, Mankikar, Shilpa, Rangan, Vangipuram S., Deshpande, Shrikant, Korman, Alan J., Almo, Steven C.

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Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity von Ho, Meng-Chiao, Wilczek, Carola, Bonanno, Jeffrey B, Xing, Li, Seznec, Janina, Matsui, Tsutomu, Carter, Lester G, Onikubo, Takashi, Kumar, P Rajesh, Chan, Man K, Brenowitz, Michael, Cheng, R Holland, Reimer, Ulf, Almo, Steven C, Shechter, David

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Histone H2A and H4 N-terminal Tails Are Positioned by the MEP50 WD Repeat Protein for Efficient Methylation by the PRMT5 Arginine Methyltransferase von Burgos, Emmanuel S., Wilczek, Carola, Onikubo, Takashi, Bonanno, Jeffrey B., Jansong, Janina, Reimer, Ulf, Shechter, David

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Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin von Leiman, Petr G, Basler, Marek, Ramagopal, Udupi A, Bonanno, Jeffrey B, Sauder, J. Michael, Pukatzki, Stefan, Burley, Stephen K, Almo, Steven C, Mekalanos, John J

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Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain von Antonysamy, Stephen, Condon, Bradley, Druzina, Zhanna, Bonanno, Jeffrey B, Gheyi, Tarun, Zhang, Feiyu, MacEwan, Iain, Zhang, Aiping, Ashok, Sheela, Rodgers, Logan, Russell, Marijane, Gately Luz, John

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HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160 von Liu, Weifeng, Chou, Ting-Fang, Garrett-Thomson, Sarah C., Seo, Goo-Young, Fedorov, Elena, Ramagopal, Udupi A., Bonanno, Jeffrey B., Wang, Qingyang, Kim, Kenneth, Garforth, Scott J., Kakugawa, Kiyokazu, Cheroutre, Hilde, Kronenberg, Mitchell, Almo, Steven C.

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Discovery of new enzymes and metabolic pathways by using structure and genome context von Zhao, Suwen, Kumar, Ritesh, Sakai, Ayano, Vetting, Matthew W., Wood, B. McKay, Brown, Shoshana, Bonanno, Jeffery B., Hillerich, Brandan S., Seidel, Ronald D., Babbitt, Patricia C., Almo, Steven C., Sweedler, Jonathan V., Gerlt, John A., Cronan, John E., Jacobson, Matthew P.

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Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3 von Liu, Weifeng, Ramagopal, Udupi, Cheng, Huiyong, Bonanno, Jeffrey B., Toro, Rafael, Bhosle, Rahul, Zhan, Chenyang, Almo, Steven C.

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Mechanism of action of a flavin-containing monooxygenase von Eswaramoorthy, S, Bonanno, J.B, Burley, S.K, Swaminathan, S

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Substrate Distortion and the Catalytic Reaction Mechanism of 5‑Carboxyvanillate Decarboxylase von Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A, Bonanno, Jeffrey B, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D, Richards, Nigel G. J, Almo, Steven C, Raushel, Frank M

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Integrative Structure–Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex von Kim, Seung Joong, Fernandez-Martinez, Javier, Sampathkumar, Parthasarathy, Martel, Anne, Matsui, Tsutomu, Tsuruta, Hiro, Weiss, Thomas M., Shi, Yi, Markina-Inarrairaegui, Ane, Bonanno, Jeffery B., Sauder, J. Michael, Burley, Stephen K., Chait, Brian T., Almo, Steven C., Rout, Michael P., Sali, Andrej

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Structural genomics: beyond the Human Genome Project von Capel, Malcolm, Swaminathan, Subramanyam, Burley, Stephen K, Studier, F. William, Gaasterland, Terry, Almo, Steven C, Chance, Mark R, Šali, Andrej, Lin, Dawei, Bonanno, Jeffrey B

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Mechanistic Basis for Functional Promiscuity in the TNF and TNF Receptor Superfamilies: Structure of the LIGHT:DcR3 Assembly von Liu, Weifeng, Zhan, Chenyang, Cheng, Huiyong, Kumar, P. Rajesh, Bonanno, Jeffrey B., Nathenson, Stanley G., Almo, Steven C.

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Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family von Odokonyero, Denis, Sakai, Ayano, Patskovsky, Yury, Malashkevich, Vladimir N., Fedorov, Alexander A., Bonanno, Jeffrey B., Fedorov, Elena V., Toro, Rafael, Agarwal, Rakhi, Wang, Chenxi, Ozerova, Nicole D. S., Yew, Wen Shan, Sauder, J. Michael, Swaminathan, Subramanyam, Burley, Stephen K., Almo, Steven C., Glasner, Margaret E.

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Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis von Herrera, Natalia G., Morano, Nicholas C., Celikgil, Alev, Georgiev, George, Malonis, Ryan J., Lee, James H., Tong, Karen, Vergnolle, Olivia, Massimi, Aldo B., Yen, Laura Y., Noble, Alex J., Kopylov, Mykhailo, Bonanno, Jeffrey B., Garrett-Thomson, Sarah C., Hayes, David B., Bortz, Robert H., Wirchnianski, Ariel S., Florez, Catalina, Laudermilch, Ethan, Haslwanter, Denise, Fels, J. Maximilian, Dieterle, M. Eugenia, Jangra, Rohit K., Barnhill, Jason, Mengotto, Amanda, Kimmel, Duncan, Daily, Johanna P., Pirofski, Liise-anne, Chandran, Kartik, Brenowitz, Michael, Garforth, Scott J., Eng, Edward T., Lai, Jonathan R., Almo, Steven C.

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Structure, Dynamics, Evolution, and Function of a Major Scaffold Component in the Nuclear Pore Complex von Sampathkumar, Parthasarathy, Kim, Seung Joong, Upla, Paula, Rice, William J., Phillips, Jeremy, Timney, Benjamin L., Pieper, Ursula, Bonanno, Jeffrey B., Fernandez-Martinez, Javier, Hakhverdyan, Zhanna, Ketaren, Natalia E., Matsui, Tsutomu, Weiss, Thomas M., Stokes, David L., Sauder, J. Michael, Burley, Stephen K., Sali, Andrej, Rout, Michael P., Almo, Steven C.

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