Genomic Classification and Prognosis in Acute Myeloid Leukemia von Papaemmanuil, Elli, Gerstung, Moritz, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Roberts, Nicola D, Potter, Nicola E, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Gundem, Gunes, Van Loo, Peter, Martincorena, Inigo, Ganly, Peter, Mudie, Laura, McLaren, Stuart, O’Meara, Sarah, Raine, Keiran, Jones, David R, Teague, Jon W, Butler, Adam P, Greaves, Mel F, Ganser, Arnold, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J

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A practical guide for mutational signature analysis in hematological malignancies von Maura, Francesco, Degasperi, Andrea, Nadeu, Ferran, Leongamornlert, Daniel, Davies, Helen, Moore, Luiza, Royo, Romina, Ziccheddu, Bachisio, Puente, Xose S., Avet-Loiseau, Herve, Campbell, Peter J., Nik-Zainal, Serena, Campo, Elias, Munshi, Nikhil, Bolli, Niccolò

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Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma von Maclachlan, Kylee H., Rustad, Even H., Derkach, Andriy, Zheng-Lin, Binbin, Yellapantula, Venkata, Diamond, Benjamin, Hultcrantz, Malin, Ziccheddu, Bachisio, Boyle, Eileen M., Blaney, Patrick, Bolli, Niccolò, Zhang, Yanming, Dogan, Ahmet, Lesokhin, Alexander M., Morgan, Gareth J., Landgren, Ola, Maura, Francesco

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Genomic patterns of progression in smoldering multiple myeloma von Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, Davies, Helen, Fulciniti, Mariateresa, Shammas, Masood A., Tai, Yu Tzu, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth, Alexandrov, Ludmil, Wedge, David C., Avet-Loiseau, Herve, Campbell, Peter, Munshi, Nikhil

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A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth

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Precision oncology for acute myeloid leukemia using a knowledge bank approach von Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott, Ultan, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J

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The pleiotropic nature of NONO, a master regulator of essential biological pathways in cancers von Ronchetti, Domenica, Traini, Valentina, Silvestris, Ilaria, Fabbiano, Giuseppina, Passamonti, Francesco, Bolli, Niccolò, Taiana, Elisa

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Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer von Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J

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Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity? von Falini, Brunangelo, Martelli, Maria Paola, Bolli, Niccolò, Sportoletti, Paolo, Liso, Arcangelo, Tiacci, Enrico, Haferlach, Torsten

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DIS3 mutations in multiple myeloma impact the transcriptional signature and clinical outcome von Todoerti, Katia, Ronchetti, Domenica, Favasuli, Vanessa, Maura, Francesco, Morabito, Fortunato, Bolli, Niccolò, Taiana, Elisa, Neri, Antonino

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Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups von Bolli, Niccolo, Biancon, Giulia, Moarii, Matahi, Gimondi, Silvia, Li, Yilong, de Philippis, Chiara, Maura, Francesco, Sathiaseelan, Vijitha, Tai, Yu-Tzu, Mudie, Laura, O’Meara, Sarah, Raine, Keiran, Teague, Jon W., Butler, Adam P., Carniti, Cristiana, Gerstung, Moritz, Bagratuni, Tina, Kastritis, Efstathios, Dimopoulos, Meletios, Corradini, Paolo, Anderson, Kenneth C., Moreau, Philippe, Minvielle, Stephane, Campbell, Peter J., Papaemmanuil, Elli, Avet-Loiseau, Herve, Munshi, Nikhil C.

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TENT5C/FAM46C modulation in vivo reveals a trade-off between antibody secretion and tumor growth in multiple myeloma von Resnati, Massimo, Pennacchio, Sara, Viviani, Lisa, Perini, Tommaso, Materozzi, Maria, Orfanelli, Ugo, Bordini, Jessica, Molteni, Raffaella, Nuvolone, Mario, Da Vià, Matteo, Lazzaroni, Francesca, Bolli, Niccolò, Cenci, Simone, Milan, Enrico

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Activation of long non-coding RNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins von Taiana, Elisa, Bandini, Cecilia, Favasuli, Vanessa Katia, Ronchetti, Domenica, Silvestris, Ilaria, Puccio, Noemi, Todoerti, Katia, Erratico, Silvia, Giannandrea, Domenica, Bolli, Niccolò, Amodio, Nicola, Ciarrocchi, Alessia, Chiaramonte, Raffaella, Torrente, Yvan, Piva, Roberto, Neri, Antonino

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CDKN2A deletion is a frequent event associated with poor outcome in patients with peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) von Maura, Francesco, Dodero, Anna, Carniti, Cristiana, Bolli, Niccolò, Magni, Martina, Monti, Valentina, Cabras, Antonello, Leongamornlert, Daniel, Abascal, Federico, Diamond, Benjamin, Rodriguez-Martin, Bernardo, Zamora, Jorge, Butler, Adam, Martincorena, Inigo, Tubio, Jose M C, Campbell, Peter J, Chiappella, Annalisa, Pruneri, Giancarlo, Corradini, Paolo

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Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma von Puccio, Noemi, Manzotti, Gloria, Mereu, Elisabetta, Torricelli, Federica, Ronchetti, Domenica, Cumerlato, Michela, Craparotta, Ilaria, Di Rito, Laura, Bolis, Marco, Traini, Valentina, Manicardi, Veronica, Fragliasso, Valentina, Torrente, Yvan, Amodio, Nicola, Bolli, Niccolò, Taiana, Elisa, Ciarrocchi, Alessia, Piva, Roberto, Neri, Antonino

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Functional Impact of Genomic Complexity on the Transcriptome of Multiple Myeloma von Ziccheddu, Bachisio, Da Vià, Matteo C, Lionetti, Marta, Maeda, Akihiro, Morlupi, Silvia, Dugo, Matteo, Todoerti, Katia, Oliva, Stefania, D'Agostino, Mattia, Corradini, Paolo, Landgren, Ola, Iorio, Francesco, Pettine, Loredana, Pompa, Alessandra, Manzoni, Martina, Baldini, Luca, Neri, Antonino, Maura, Francesco, Bolli, Niccolò

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Next-Generation Sequencing for Clinical Management of Multiple Myeloma: Ready for Prime Time? von Bolli, Niccolo, Genuardi, Elisa, Ziccheddu, Bachisio, Martello, Marina, Oliva, Stefania, Terragna, Carolina

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Early Relapse Risk in Patients with Newly Diagnosed Multiple Myeloma Characterized by Next-generation Sequencing von D'Agostino, Mattia, Zaccaria, Gian Maria, Ziccheddu, Bachisio, Rustad, Even H, Genuardi, Elisa, Capra, Andrea, Oliva, Stefania, Auclair, Daniel, Yesil, Jennifer, Colucci, Paola, Keats, Jonathan J, Gambella, Manuela, Bringhen, Sara, Larocca, Alessandra, Boccadoro, Mario, Bolli, Niccolò, Maura, Francesco, Gay, Francesca

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DIS3 depletion in multiple myeloma causes extensive perturbation in cell cycle progression and centrosome amplification von Favasuli, Vanessa K, Ronchetti, Domenica, Silvestris, Ilaria, Puccio, Noemi, Fabbiano, Giuseppina, Traini, Valentina, Todoerti, Katia, Erratico, Silvia, Ciarrocchi, Alessia, Fragliasso, Valentina, Giannandrea, Domenica, Tumiatti, Francesca, Chiaramonte, Raffaella, Torrente, Yvan, Finelli, Palma, Morelli, Eugenio, Munshi, Nikhil C, Bolli, Niccolò, Neri, Antonino, Taìana, Elisa

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Value and limitations of targeted next-generation sequencing in idiopathic hypereosinophilia: an integrative diagnostic tool in challenging cases von Cattaneo, Daniele, Marchetti, Alfredo, Bucelli, Cristina, Galli, Nicole, Lionetti, Marta, Bellani, Valentina, Gianelli, Umberto, Passamonti, Francesco, Bolli, Niccolò, Iurlo, Alessandra

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