Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer von Stanislawski, Thomas, Voss, Ralf-Holger, Lotz, Carina, Sadovnikova, Elena, Willemsen, Ralph A., Kuball, Jürgen, Ruppert, Thomas, Bolhuis, Reinder L. H., Melief, Cornelius J., Huber, Christoph, Stauss, Hans J., Theobald, Matthias

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T Cell Retargeting with MHC Class I-Restricted Antibodies: The CD28 Costimulatory Domain Enhances Antigen-Specific Cytotoxicity and Cytokine Production von Willemsen, Ralph A, Ronteltap, Cees, Chames, Patrick, Debets, Reno, Bolhuis, Reinder L. H

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TCR-Like Human Antibodies Expressed on Human CTLs Mediate Antibody Affinity-Dependent Cytolytic Activity von Chames, Patrick, Willemsen, Ralph A, Rojas, Gertrudis, Dieckmann, Detlef, Rem, Louise, Schuler, Gerold, Bolhuis, Reinder L, Hoogenboom, Hennie R

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Repeated Administrations of Interleukin (IL)-12 Are Associated with Persistently Elevated Plasma Levels of IL-10 and Declining IFN-γ, Tumor Necrosis Factor-α, IL-6, and IL-8 Respon... von PORTIELJE, Johanna E. A, LAMERS, Cor H. J, KRUIT, Wim H. J, SPARREBOOM, Alex, BOLHUIS, Reinder L. H, STOTER, Gerrit, HUBER, Christoph, GRATAMA, Jan W

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Tetramer-based quantification of cytomegalovirus (CMV)–specific CD8+ T lymphocytes in T-cell–depleted stem cell grafts and after transplantation may identify patients at risk for p... von Gratama, Jan W., van Esser, Joost W.J., Lamers, Cor H.J., Tournay, Claire, Löwenberg, Bob, Bolhuis, Reinder L.H., Cornelissen, Jan J.

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Protocol for gene transduction and expansion of human T lymphocytes for clinical immunogene therapy of cancer von Lamers, Cor H J, Willemsen, Ralph A, Luider, Barbara A, Debets, Reno, Bolhuis, Reinder L H

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Flexible and sensitive method to functionally validate tumor-specific receptors via activation of NFAT von Schaft, Niels, Lankiewicz, Birgit, Gratama, Jan Willem, Bolhuis, Reinder L.H., Debets, Reno

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An entirely humanized CD3 ζ‐chain signaling receptor that directs peripheral blood t cells to specific lysis of carcinoembryonic antigen–positive tumor cells von Hombach, Andreas, Schneider, Claudia, Sent, Dagmar, Koch, Dimitra, Willemsen, Ralph A., Diehl, Volker, Kruis, Wolfgang, Bolhuis, Reinder L., Pohl, Christoph, Abken, Hinrich

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Interleukin 12 induces activation of fibrinolysis and coagulation in humans von Portielje, Johanna E. A., Kruit, Wim H. J., Eerenberg, Anke J. M., Schuler, Martin, Sparreboom, Alex, Lamers, Cor H. J., Bolhuis, Reinder L. H., Stoter, Gerrit, Huber, Christoph, Hack, C. Erik

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Genetic engineering of T cell specificity for immunotherapy of cancer von Willemsen, Ralph A, Debets, Reno, Chames, Patrick, Bolhuis, Reinder L.H

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Regression of Advanced Ovarian Carcinoma by Intraperitoneal Treatment With Autologous TLymphocytes Retargeted by a Bispecific Monoclonal Antibody von Canevari, Silvana, Stoter, Gerrit, Arienti, Flavio, Bolis, Giorgio, Colnaghi, Maria I., Di Re, Emanuela M., Eggermont, Alexander M. M., Goey, S. Hoo, Gratama, Jan W., Lamers, Cor H. J., Nooy, Marianne A., Parmiani, Giorgio, Raspagliesi, Francesco, Ravagnani, Ferdinando, Scarfone, Giovanna, Trimbos, J. Baptist, Warnaar, Sven O., Bolhuis, Reinder L. H.

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Phase I Study of Subcutaneously Administered Recombinant Human Interleukin 12 in Patients with Advanced Renal Cell Cancer von PORTIELJE, J. E. A, KRUIT, W. H. J, AULITZKY, W. E, SCHULER, M, BECK, J, LAMERS, C. H. J, STOTER, G, HUBER, C, DE BOER-DENNERT, M, RAKHIT, A, BOLHUIS, R. L. H

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A T-cell receptor γ/CD3 complex found on cloned functional lymphocytes von Borst, Jannie, van de Griend, René J., van Oostveen, Johan W., Ang, Siew-Lan, Melief, Cornelis J., Seidman, J. G., Bolhuis, Reinder L. H.

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Restoration of expression of signal-transduction molecules in lymphocytes from patients with metastatic renal cell cancer after combination immunotherapy von GRATAMA, J. W, ZEA, A. H, BOLHUIS, R. L. H, OCHOA, A. C

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Inhibition of bispecific monoclonal antibody (bsAb)‐targeted cytolysis by human anti‐mouse antibodies in ovarian carcinoma patients treated with bsAb‐targeted activated T‐lymphocyt... von Lamers, Cor H. J., Gratama, Jan W., Warnaar, Sven O., Stoter, Gerrit, Bolhuis, Reinder L. H.

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Large-scale production of natural cytokines during activation and expansion of human T lymphocytes in hollow fiber bioreactor cultures von LAMERS, C. H. J, GRATAMA, J. W, LUIDER-VRIELING, B, BOLHUIS, R. L. H, BAST, E. J. E. G

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Recognition by Human V$_\gamma$9/V$_\delta$2 T Cells of a GroEL Homolog on Daudi Burkitt's Lymphoma Cells von Fisch, Paul, Malkovsky, Miroslav, Kovats, Susan, Sturm, Els, Braakman, Erik, Klein, Bruce S., Voss, Stephan D., Morrissey, Lawrence W., DeMars, Robert, Welch, William J., Reinder L. H. Bolhuis, Sondel, Paul M.

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Icam ‐ melanoma cells are relatively resistant to cd3‐mediated t‐cell lysis von Braakman, Eric, Goedegebuure, Peter S., Vreugdenhil, Rea J., Segal, David M., Shaw, Stephen, Bolhuis, Reinder L. H.

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Chimeric bispecific OC/TR monoclonal antibody mediates lysis of tumor cells expressing the folate-binding protein (MOv18) and displays decreased immunogenicity in patients von Luiten, R M, Warnaar, S O, Sanborn, D, Lamers, C H, Bolhuis, R L, Litvinov, S V, Zurawski, Jr, V R, Coney, L R

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Modulation of immune parameters in patients with metastatic renal‐cell cancer receiving combination immunotherapy (IL‐2, IFNα and autologous IL‐2‐activated lymphocytes) von Gratama, Jan W., Schmitz, Paul I. M., Goey, S. Hoo, Lamers, Cor H. J., Stoter, Gerrit, Bolhuis, Reinder L. H.

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