VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications von Robciuc, Marius R., Kivelä, Riikka, Williams, Ian M., de Boer, Jan Freark, van Dijk, Theo H., Elamaa, Harri, Tigistu-Sahle, Feven, Molotkov, Dmitry, Leppänen, Veli-Matti, Käkelä, Reijo, Eklund, Lauri, Wasserman, David H., Groen, Albert K., Alitalo, Kari

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Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice von Schonewille, Marleen, Freark de Boer, Jan, Mele, Laura, Wolters, Henk, Bloks, Vincent W., Wolters, Justina C., Kuivenhoven, Jan A., Tietge, Uwe J.F., Brufau, Gemma, Groen, Albert K.

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Glucose‐6‐Phosphate Regulates Hepatic Bile Acid Synthesis in Mice von Hoogerland, Joanne A., Lei, Yu, Wolters, Justina C., Boer, Jan Freark, Bos, Trijnie, Bleeker, Aycha, Mulder, Niels L., Dijk, Theo H., Kuivenhoven, Jan A., Rajas, Fabienne, Mithieux, Gilles, Haeusler, Rebecca A., Verkade, Henkjan J., Bloks, Vincent W., Kuipers, Folkert, Oosterveer, Maaike H.

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Reversal of insulin resistance in people with obesity by lifestyle‐induced weight loss does not impact the proportion of circulating 12α‐hydroxylated bile acids von Palmiotti, Anna, Berk, Kirsten A., Koehorst, Martijn, Hovingh, Milaine V., Pranger, Alle T., Faassen, Martijn, Boer, Jan Freark, Valk, Eline S., Rossum, Elisabeth F. C., Mulder, Monique T., Kuipers, Folkert

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Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation von Zhou, Enchen, Ge, Xiaoke, Nakashima, Hiroyuki, Li, Rumei, van der Zande, Hendrik J P, Liu, Cong, Li, Zhuang, Müller, Christoph, Bracher, Franz, Mohammed, Yassene, de Boer, Jan Freark, Kuipers, Folkert, Guigas, Bruno, Glass, Christopher K, Rensen, Patrick C N, Giera, Martin, Wang, Yanan

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Response to Spontaneous Cholemia in C57BL/6 Mice Predisposes to Liver Cancer in NASH von Ronda, Onne A.H.O., Bloks, Vincent W., De Boer, Jan-Freark, Kuipers, Folkert, Verkade, Henkjan J.

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Impaired Bile Acid Metabolism and Gut Dysbiosis in Mice Lacking Lysosomal Acid Lipase von Sachdev, Vinay, Duta-Mare, Madalina, Korbelius, Melanie, Vujic, Nemanja, Leopold, Christina, Freark de Boer, Jan, Rainer, Silvia, Fickert, Peter, Kolb, Dagmar, Kuipers, Folkert, Radovic, Branislav, Gorkiewicz, Gregor, Kratky, Dagmar

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A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice[S] von de Boer, Jan Freark, Verkade, Esther, Mulder, Niels L., de Vries, Hilde D., Huijkman, Nicolette, Koehorst, Martijn, Boer, Theo, Wolters, Justina C., Bloks, Vincent W., van de Sluis, Bart, Kuipers, Folkert

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Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice von Heida, Andries, van Dijk, Theo, Smit, Marieke, Koehorst, Martijn, Koster, Mirjam, Kloosterhuis, Niels, Havinga, Rick, Bloks, Vincent W, Wolters, Justina C, de Bruin, Alain, Kuivenhoven, Jan Albert, de Boer, Jan Freark, Kuipers, Folkert, van de Sluis, Bart

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ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma von Annema, Wijtske, Dikkers, Arne, Freark de Boer, Jan, Gautier, Thomas, Rensen, Patrick C.N., Rader, Daniel J., Tietge, Uwe J.F.

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Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion von Jakulj, Lily, van Dijk, Theo H., de Boer, Jan Freark, Kootte, Ruud S., Schonewille, Marleen, Paalvast, Yared, Boer, Theo, Bloks, Vincent W., Boverhof, Renze, Nieuwdorp, Max, Beuers, Ulrich H.W., Stroes, Erik S.G., Groen, Albert K.

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Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles von Zhang, Boyan, Kuipers, Folkert, de Boer, Jan Freark, Kuivenhoven, Jan Albert

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Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice von Freark de Boer, Jan, Annema, Wijtske, Schreurs, Marijke, van der Veen, Jelske N., van der Giet, Markus, Nijstad, Niels, Kuipers, Folkert, Tietge, Uwe J.F.

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HDL Cholesterol Efflux Predicts Graft Failure in Renal Transplant Recipients von Annema, Wijtske, Dikkers, Arne, de Boer, Jan Freark, Dullaart, Robin P F, Sanders, Jan-Stephan F, Bakker, Stephan J L, Tietge, Uwe J F

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Simvastatin and bezafibrate increase cholesterol efflux in men with type 2 diabetes von Triolo, Michela, Annema, Wijtske, de Boer, Jan Freark, Tietge, Uwe J. F., Dullaart, Robin P. F.

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Intestinal Farnesoid X Receptor Modulates Duodenal Surface Area but Does Not Control Glucose Absorption in Mice von Yang, Jiufang, van Dijk, Theo H, Koehorst, Martijn, Havinga, Rick, de Boer, Jan Freark, Kuipers, Folkert, van Zutphen, Tim

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Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70−/− mice by reducing fat absorption von Li, Rumei, Palmiotti, Anna, de Vries, Hilde D., Hovingh, Milaine V., Koehorst, Martijn, Mulder, Niels L., Zhang, Yue, Kats, Kim, Bloks, Vincent W., Fu, Jingyuan, Verkade, Henkjan J., de Boer, Jan Freark, Kuipers, Folkert

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The efficacy of alginate encapsulated CHO-K1 single chain-TRAIL producer cells in the treatment of brain tumors von KUIJLEN, Jos M. A, DE HAAN, Bart J, HELFRICH, Wijnand, DE BOER, Jan-Freark, SAMPLONIUS, Douwe, MOOIJ, Jan Jakob A, DE VOS, Paul

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Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A2[S] von Annema, Wijtske, Nijstad, Niels, Tölle, Markus, de Boer, Jan Freark, Buijs, Ruben V.C., Heeringa, Peter, van der Giet, Markus, Tietge, Uwe J.F.

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Impaired HDL cholesterol efflux in metabolic syndrome is unrelated to glucose tolerance status: the CODAM study von Annema, Wijtske, Dikkers, Arne, de Boer, Jan Freark, van Greevenbroek, Marleen M. J., van der Kallen, Carla J. H., Schalkwijk, Casper G., Stehouwer, Coen D. A., Dullaart, Robin P. F., Tietge, Uwe J. F.

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