Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects von Dempster, Joshua M., Boyle, Isabella, Vazquez, Francisca, Root, David E., Boehm, Jesse S., Hahn, William C., Tsherniak, Aviad, McFarland, James M.

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A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis von Zou, Yilong, Palte, Michael J., Deik, Amy A., Li, Haoxin, Eaton, John K., Wang, Wenyu, Tseng, Yuen-Yi, Deasy, Rebecca, Kost-Alimova, Maria, Dančík, Vlado, Leshchiner, Elizaveta S., Viswanathan, Vasanthi S., Signoretti, Sabina, Choueiri, Toni K., Boehm, Jesse S., Wagner, Bridget K., Doench, John G., Clish, Clary B., Clemons, Paul A., Schreiber, Stuart L.

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The Cancer Dependency Map enables drug mechanism‐of‐action investigations von Vazquez, Francisca, Boehm, Jesse S

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Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells von Meyers, Robin M, Bryan, Jordan G, McFarland, James M, Weir, Barbara A, Sizemore, Ann E, Xu, Han, Dharia, Neekesh V, Montgomery, Phillip G, Cowley, Glenn S, Pantel, Sasha, Goodale, Amy, Lee, Yenarae, Ali, Levi D, Jiang, Guozhi, Lubonja, Rakela, Harrington, William F, Strickland, Matthew, Wu, Ting, Hawes, Derek C, Zhivich, Victor A, Wyatt, Meghan R, Kalani, Zohra, Chang, Jaime J, Okamoto, Michael, Stegmaier, Kimberly, Golub, Todd R, Boehm, Jesse S, Vazquez, Francisca, Root, David E, Hahn, William C, Tsherniak, Aviad

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Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration von McFarland, James M., Ho, Zandra V., Kugener, Guillaume, Dempster, Joshua M., Montgomery, Phillip G., Bryan, Jordan G., Krill-Burger, John M., Green, Thomas M., Vazquez, Francisca, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Tsherniak, Aviad

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Global computational alignment of tumor and cell line transcriptional profiles von Warren, Allison, Chen, Yejia, Jones, Andrew, Shibue, Tsukasa, Hahn, William C., Boehm, Jesse S., Vazquez, Francisca, Tsherniak, Aviad, McFarland, James M.

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Recurrent and functional regulatory mutations in breast cancer von Rheinbay, Esther, Parasuraman, Prasanna, Grimsby, Jonna, Tiao, Grace, Engreitz, Jesse M., Kim, Jaegil, Lawrence, Michael S., Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Cortes, Maria L., Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Gabriel, Stacey B., Meyerson, Matthew, Golub, Todd R., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Lander, Eric S., Getz, Gad

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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets von Dempster, Joshua M., Pacini, Clare, Pantel, Sasha, Behan, Fiona M., Green, Thomas, Krill-Burger, John, Beaver, Charlotte M., Younger, Scott T., Zhivich, Victor, Najgebauer, Hanna, Allen, Felicity, Gonçalves, Emanuel, Shepherd, Rebecca, Doench, John G., Yusa, Kosuke, Vazquez, Francisca, Parts, Leopold, Boehm, Jesse S., Golub, Todd R., Hahn, William C., Root, David E., Garnett, Mathew J., Tsherniak, Aviad, Iorio, Francesco

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An ecosystem of cancer cell line factories to support a cancer dependency map von Boehm, Jesse S., Golub, Todd R.

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Acute and long-term effects of Δ9-tetrahydrocannabinol on object recognition and anxiety-like activity are age- and strain-dependent in mice von Kasten, C.R., Zhang, Y., Boehm, S.L.

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Neurofeedback: A promising tool for the self-regulation of emotion networks von Johnston, S.J., Boehm, S.G., Healy, D., Goebel, R., Linden, D.E.J.

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PRKACA mediates resistance to HER2-targeted therapy in breast cancer cells and restores anti-apoptotic signaling von Moody, S E, Schinzel, A C, Singh, S, Izzo, F, Strickland, M R, Luo, L, Thomas, S R, Boehm, J S, Kim, S Y, Wang, Z C, Hahn, W C

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High-throughput Phenotyping of Lung Cancer Somatic Mutations von Berger, Alice H., Brooks, Angela N., Wu, Xiaoyun, Shrestha, Yashaswi, Chouinard, Candace, Piccioni, Federica, Bagul, Mukta, Kamburov, Atanas, Imielinski, Marcin, Hogstrom, Larson, Zhu, Cong, Yang, Xiaoping, Pantel, Sasha, Sakai, Ryo, Watson, Jacqueline, Kaplan, Nathan, Campbell, Joshua D., Singh, Shantanu, Root, David E., Narayan, Rajiv, Natoli, Ted, Lahr, David L., Tirosh, Itay, Tamayo, Pablo, Getz, Gad, Wong, Bang, Doench, John, Subramanian, Aravind, Golub, Todd R., Meyerson, Matthew, Boehm, Jesse S.

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Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells von Scholl, Claudia, Fröhling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Döhner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Jacks, Tyler, Hahn, William C., Gilliland, D. Gary

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Systematic morphological profiling of human gene and allele function via Cell Painting von Rohban, Mohammad Hossein, Singh, Shantanu, Wu, Xiaoyun, Berthet, Julia B, Bray, Mark-Anthony, Shrestha, Yashaswi, Varelas, Xaralabos, Boehm, Jesse S, Carpenter, Anne E

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Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area von Linsenbardt, D.N, Boehm, S.L

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Towards systematic functional characterization of cancer genomes von Hahn, William C, Boehm, Jesse S

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Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development von Giannikou, Krinio, Malinowska, Izabela A, Pugh, Trevor J, Yan, Rachel, Tseng, Yuen-Yi, Oh, Coyin, Kim, Jaegil, Tyburczy, Magdalena E, Chekaluk, Yvonne, Liu, Yang, Alesi, Nicola, Finlay, Geraldine A, Wu, Chin-Lee, Signoretti, Sabina, Meyerson, Matthew, Getz, Gad, Boehm, Jesse S, Henske, Elizabeth P, Kwiatkowski, David J

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer von Cheung, Hiu Wing, Cowley, Glenn S, Weir, Barbara A, Boehm, Jesse S, Rusin, Scott, Scott, Justine A, East, Alexandra, Ali, Levi D, Lizotte, Patrick H, Wong, Terence C, Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H, Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Ren, Yin, Drapkin, Ronny, Bhatia, Sangeeta N, Mesirov, Jill P, Garraway, Levi A, Meyerson, Matthew, Lander, Eric S, Root, David E, Hahn, William C

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Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles von Kim, Eejung, Ilic, Nina, Shrestha, Yashaswi, Zou, Lihua, Kamburov, Atanas, Zhu, Cong, Yang, Xiaoping, Lubonja, Rakela, Tran, Nancy, Nguyen, Cindy, Lawrence, Michael S, Piccioni, Federica, Bagul, Mukta, Doench, John G, Chouinard, Candace R, Wu, Xiaoyun, Hogstrom, Larson, Natoli, Ted, Tamayo, Pablo, Horn, Heiko, Corsello, Steven M, Lage, Kasper, Root, David E, Subramanian, Aravind, Golub, Todd R, Getz, Gad, Boehm, Jesse S, Hahn, William C

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