Ozanimod (RPC1063) is a potent sphingosine‐1‐phosphate receptor‐1 (S1P1) and receptor‐5 (S1P5) agonist with autoimmune disease‐modifying activity von Scott, F L, Clemons, B, Brooks, J, Brahmachary, E, Powell, R, Dedman, H, Desale, H G, Timony, G A, Martinborough, E, Rosen, H, Roberts, E, Boehm, M F, Peach, R J

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Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists von Mukherjee, Ranjan, Davies, Peter J. A, Crombie, Diane L, Bischoff, Eric D, Cesario, Rosemary M, Jow, Lily, Hamann, Lawrence G, Boehm, Marcus F, Mondon, Carl E, Nadzan, Alex M, Paterniti, James R, Heyman, Richard A

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A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors von Burrows, Francis J, Kamal, Adeela, Thao, Lia, Sensintaffar, John, Zhang, Lin, Boehm, Marcus F, Fritz, Lawrence C

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Novel (2E,4E,6Z)-7-(2-Alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic Acid Retinoid X Receptor Modulators Are Active in Models of Type 2 Diabetes von Michellys, P. Y, Ardecky, R. J, Chen, J. H, Crombie, D. L, Etgen, G. J, Faulkner, A. L, Faul, M. M, Grese, T. A, Heyman, R. A, Karanewsky, D. S, Klausing, K, Leibowitz, M. D, Liu, S, Mais, D. A, Mapes, C. M, Marschke, K. B, Reifel-Miller, A, Ogilvie, K. M, Rungta, D, Thompson, A. W, Tyhonas, J. S, Boehm, M. F

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Therapeutic and diagnostic implications of Hsp90 activation von Kamal, Adeela, Boehm, Marcus F, Burrows, Francis J

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Design and Synthesis of Potent Retinoid X Receptor Selective Ligands That Induce Apoptosis in Leukemia Cells von Boehm, Marcus F, Zhang, Lin, Zhi, Lin, McClurg, Michael R, Berger, Elain, Wagoner, Murriel, Mais, Dale E, Suto, Carla M, Davies, Peter J. A, Heyman, Richard A, Nadzan, Alex M

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Activation of mammalian retinoid X receptors by the insect growth regulator methoprene von Harmon, M A, Boehm, M F, Heyman, R A, Mangelsdorf, D J

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Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism von Allegretto, E A, McClurg, M R, Lazarchik, S B, Clemm, D L, Kerner, S A, Elgort, M G, Boehm, M F, White, S K, Pike, J W, Heyman, R A

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Design and synthesis of benzofused heterocyclic RXR modulators von Gernert, D.L., Neel, D.A., Boehm, M.F., Leibowitz, M.D., Mais, D.A., Michellys, P.Y., Rungta, D., Reifel-Miller, A., Grese, T.A.

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Synthesis of Retinoid X Receptor-Specific Ligands That Are Potent Inducers of Adipogenesis in 3T3-L1 Cells von Canan Koch, Stacie S, Dardashti, Laura J, Cesario, Rosemary M, Croston, Glenn E, Boehm, Marcus F, Heyman, Richard A, Nadzan, Alex M

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Engineering Orthogonal Ligand−Receptor Pairs from “Near Drugs” von Doyle, Donald F, Braasch, Dwaine A, Jackson, Laurie K, Weiss, Harald E, Boehm, Marcus F, Mangelsdorf, David J, Corey, David R

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9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation von Bissonnette, Reid P., Brunner, Thomas, Lazarchik, Steven B., Yoo, Nam Jin, Boehm, Marcus F., Green, Douglas R., Heyman, Richard A.

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Cloning and expression of goldfish opsin sequences von Johnson, Randy L, Grant, Kathryn B, Zankel, Todd C, Boehm, Marcus F, Merbs, Shannath L, Nathans, Jeremy, Nakanishi, Koji

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Synthesis of high specific activity [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties von BOEHM, M. F, MCCLURG, M. R, PATHIRANA, C, MANGELSDORF, D, WHITE, S. K, HEBERT, J, WINN, D, GOLDMAN, M. E, HEYMAN, R. A

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Synthesis and Structure-Activity Relationships of Novel Retinoid X Receptor-Selective Retinoids von Boehm, Marcus F, Zhang, Lin, Badea, Beth Ann, White, Steven K, Mais, Dale E, Berger, Elaine, Suto, Carla M, Goldman, Mark E, Heyman, Richard A

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A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice von SHALINSKY, D. R, BISCHOFF, E. D, LAMPH, W. W, ZHANG, L, BOEHM, M. F, DAVIES, P. J. A, NADZAN, A. M, HEYMAN, R. A

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Synthesis and Characterization of Heteroarotinoids Demonstrate Structure Specificity Relationships von Benbrook, Doris M, Subramanian, Shankar, Gale, Jonathan B, Liu, Shengquan, Brown, Chad W, Boehm, Marcus F, Berlin, K. Darrell

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Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells von Angulo, A, Suto, C, Boehm, M F, Heyman, R A, Ghazal, P

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Discovery of Novel Retinoic Acid Receptor Agonists Having Potent Antiproliferative Activity in Cervical Cancer Cells von Zhang, Lin, Nadzan, Alex M, Heyman, Richard A, Love, Deborah L, Mais, Dale E, Croston, Glenn, Lamph, William W, Boehm, Marcus F

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Novel nonsecosteroidal vitamin D receptor modulator inhibits the growth of LNCaP xenograft tumors in athymic mice without increased serum calcium von Polek, Tara C., Murthy, Shalini, Blutt, Sarah E., Boehm, Marcus F., Zou, Aihua, Weigel, Nancy L., Allegretto, Elizabeth A.

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