NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas von Meder, Lydia, König, Katharina, Ozretić, Luka, Schultheis, Anne M., Ueckeroth, Frank, Ade, Carsten P., Albus, Kerstin, Boehm, Diana, Rommerscheidt‐Fuss, Ursula, Florin, Alexandra, Buhl, Theresa, Hartmann, Wolfgang, Wolf, Jürgen, Merkelbach‐Bruse, Sabine, Eilers, Martin, Perner, Sven, Heukamp, Lukas C., Buettner, Reinhard

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Rationale for Treatment of Metastatic Squamous Cell Carcinoma of the Lung Using Fibroblast Growth Factor Receptor Inhibitors von Göke, Friederike, MD, Franzen, Alina, BS, Menon, Roopika, MSc, Goltz, Diane, MD, Kirsten, Robert, Boehm, Diana, BS, Vogel, Wenzel, BS, Göke, Antonia, BS, Scheble, Veit, MD, Ellinger, Joerg, MD, Gerigk, Ulrich, MD, Fend, Falko, MD, Wagner, Patrick, MD, Schroeck, Andreas, MD, Perner, Sven, MD

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Fibroblast growth factor receptor 1 amplification is a common event in squamous cell carcinoma of the head and neck von Göke, Friederike, Bode, Maike, Franzen, Alina, Kirsten, Robert, Goltz, Diane, Göke, Antonia, Sharma, Rakesh, Boehm, Diana, Vogel, Wenzel, Wagner, Patrick, Lengerke, Claudia, Kristiansen, Glen, Kirfel, Jutta, Van Bremen, Tobias, Bootz, Friedrich, Heasley, Lynn E, Schröck, Andreas, Perner, Sven

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Nonamplified FGFR1 is a growth driver in malignant pleural mesothelioma von Marek, Lindsay A, Hinz, Trista K, von Mässenhausen, Anne, Olszewski, Kyle A, Kleczko, Emily K, Boehm, Diana, Weiser-Evans, Mary C, Nemenoff, Raphael A, Hoffmann, Hans, Warth, Arne, Gozgit, Joseph M, Perner, Sven, Heasley, Lynn E

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Fibroblast growth factor receptor 1 gene amplification in pancreatic ductal adenocarcinoma von Lehnen, Nils C, von Mässenhausen, Anne, Kalthoff, Holger, Zhou, Hui, Glowka, Tim, Schütte, Ute, Höller, Tobias, Riesner, Katarina, Boehm, Diana, Merkelbach-Bruse, Sabine, Kirfel, Jutta, Perner, Sven, Gütgemann, Ines

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‘A jack of all trades’: the role of PIs in the establishment and management of collaborative networks in scientific knowledge commercialisation von Boehm, Diana Nadine, Hogan, Teresa

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Science-to-business collaborations: A science-to-business marketing perspective on scientific knowledge commercialization von Boehm, Diana Nadine, Hogan, Teresa

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Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer von Peifer, Martin, Fernández-Cuesta, Lynnette, Sos, Martin L, George, Julie, Seidel, Danila, Kasper, Lawryn H, Plenker, Dennis, Leenders, Frauke, Sun, Ruping, Zander, Thomas, Menon, Roopika, Koker, Mirjam, Dahmen, Ilona, Müller, Christian, Di Cerbo, Vincenzo, Schildhaus, Hans-Ulrich, Altmüller, Janine, Baessmann, Ingelore, Becker, Christian, de Wilde, Bram, Vandesompele, Jo, Böhm, Diana, Ansén, Sascha, Gabler, Franziska, Wilkening, Ines, Heynck, Stefanie, Heuckmann, Johannes M, Lu, Xin, Carter, Scott L, Cibulskis, Kristian, Banerji, Shantanu, Getz, Gad, Park, Kwon-Sik, Rauh, Daniel, Grütter, Christian, Fischer, Matthias, Pasqualucci, Laura, Wright, Gavin, Wainer, Zoe, Russell, Prudence, Petersen, Iver, Chen, Yuan, Stoelben, Erich, Ludwig, Corinna, Schnabel, Philipp, Hoffmann, Hans, Muley, Thomas, Brockmann, Michael, Engel-Riedel, Walburga, Muscarella, Lucia A, Fazio, Vito M, Groen, Harry, Timens, Wim, Sietsma, Hannie, Thunnissen, Erik, Smit, Egbert, Heideman, Daniëlle A M, Snijders, Peter J F, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John, Solberg, Steinar, Brustugun, Odd Terje, Lund-Iversen, Marius, Sänger, Jörg, Clement, Joachim H, Soltermann, Alex, Moch, Holger, Weder, Walter, Solomon, Benjamin, Soria, Jean-Charles, Validire, Pierre, Besse, Benjamin, Brambilla, Elisabeth, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Schneider, Peter M, Hallek, Michael, Pao, William, Meyerson, Matthew, Sage, Julien, Shendure, Jay, Schneider, Robert, Büttner, Reinhard, Wolf, Jürgen, Nürnberg, Peter, Perner, Sven, Heukamp, Lukas C, Brindle, Paul K, Haas, Stefan, Thomas, Roman K

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Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer von Brägelmann, Johannes, Klümper, Niklas, Offermann, Anne, von Mässenhausen, Anne, Böhm, Diana, Deng, Mario, Queisser, Angela, Sanders, Christine, Syring, Isabella, Merseburger, Axel S, Vogel, Wenzel, Sievers, Elisabeth, Vlasic, Ignacija, Carlsson, Jessica, Andrén, Ove, Brossart, Peter, Duensing, Stefan, Svensson, Maria A, Adler, David, Kirfel, Jutta, Perner, Sven

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FGFR1 mRNA and Protein Expression, not Gene Copy Number, Predict FGFR TKI Sensitivity across All Lung Cancer Histologies von WYNES, Murry W, HINZ, Trista K, DZIADZIUSZKO, Rafal, JASSEM, Jacek, WOJTYLAK, Szymon, SEJDA, Aleksandra, GOZGIT, Joseph M, BUNN, Paul A, CAMIDGE, D. Ross, TAN, Aik-Choon, HIRSCH, Fred R, HEASLEY, Lynn E, DEXIANG GAO, MARTINI, Michael, MAREK, Lindsay A, WARE, Kathryn E, EDWARDS, Michael G, BÖHM, Diana, PERNER, Sven, HELFRICH, Barbara A

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FGFR1 Expression Levels Predict BGJ398 Sensitivity of FGFR1-Dependent Head and Neck Squamous Cell Cancers von Göke, Friederike, Franzen, Alina, Hinz, Trista K, Marek, Lindsay A, Yoon, Petros, Sharma, Rakesh, Bode, Maike, von Maessenhausen, Anne, Lankat-Buttgereit, Brigitte, Göke, Antonia, Golletz, Carsten, Kirsten, Robert, Boehm, Diana, Vogel, Wenzel, Kleczko, Emily K, Eagles, Justin R, Hirsch, Fred R, Van Bremen, Tobias, Bootz, Friedrich, Schroeck, Andreas, Kim, Jihye, Tan, Aik-Choon, Jimeno, Antonio, Heasley, Lynn E, Perner, Sven

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Differences in Frequency of ERG Oncoprotein Expression Between Index Tumors of Caucasian and African American Patients With Prostate Cancer von Rosen, Philip, Pfister, David, Young, Denise, Petrovics, Gyorgy, Chen, Yongmei, Cullen, Jennifer, Böhm, Diana, Perner, Sven, Dobi, Albert, McLeod, David G, Sesterhenn, Isabell A, Srivastava, Shiv

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Exome enrichment and SOLiD sequencing of formalin fixed paraffin embedded (FFPE) prostate cancer tissue von Menon, Roopika, Deng, Mario, Boehm, Diana, Braun, Martin, Fend, Falko, Boehm, Detlef, Biskup, Saskia, Perner, Sven

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Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data von Fernandez-Cuesta, Lynnette, Sun, Ruping, Menon, Roopika, George, Julie, Lorenz, Susanne, Meza-Zepeda, Leonardo A, Peifer, Martin, Plenker, Dennis, Heuckmann, Johannes M, Leenders, Frauke, Zander, Thomas, Dahmen, Ilona, Koker, Mirjam, Schöttle, Jakob, Ullrich, Roland T, Altmüller, Janine, Becker, Christian, Nürnberg, Peter, Seidel, Henrik, Böhm, Diana, Göke, Friederike, Ansén, Sascha, Russell, Prudence A, Wright, Gavin M, Wainer, Zoe, Solomon, Benjamin, Petersen, Iver, Clement, Joachim H, Sänger, Jörg, Brustugun, Odd-Terje, Helland, Åslaug, Solberg, Steinar, Lund-Iversen, Marius, Buettner, Reinhard, Wolf, Jürgen, Brambilla, Elisabeth, Vingron, Martin, Perner, Sven, Haas, Stefan A, Thomas, Roman K

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MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration‐resistant prostate cancer von Shaikhibrahim, Zaki, Menon, Roopika, Braun, Martin, Offermann, Anne, Queisser, Angela, Boehm, Diana, Vogel, Wenzel, Rüenauver, Kerstin, Ruiz, Christian, Zellweger, Tobias, Svensson, Maria, Andren, Ove, Kristiansen, Glen, Wernert, Nicolas, Bubendorf, Lukas, Kirfel, Jutta, Biskup, Saskia, Perner, Sven

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Comprehensive analysis of the transcriptional profile of the Mediator complex across human cancer types von Syring, Isabella, Klümper, Niklas, Offermann, Anne, Braun, Martin, Deng, Mario, Boehm, Diana, Queisser, Angela, von Mässenhausen, Anne, Brägelmann, Johannes, Vogel, Wenzel, Schmidt, Doris, Majores, Michael, Schindler, Anne, Kristiansen, Glen, Müller, Stefan C, Ellinger, Jörg, Adler, David, Perner, Sven

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Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer von Menon, Roopika, Deng, Mario, Rüenauver, Kerstin, Queisser, Angela, Pfeifer, Martin, Offermann, Anne, Boehm, Diana, Vogel, Wenzel, Scheble, Veit, Fend, Falko, Kristiansen, Glen, Wernert, Nicolas, Oberbeckmann, Nicole, Biskup, Saskia, Rubin, Mark A, Shaikhibrahim, Zaki, Perner, Sven

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Abstract C27: Whole-exome sequencing identifies potential therapeutic targets for castration-resistant prostate cancer von Menon, Roopika, Deng, Mario, Boehm, Diana, Fend, Falko, Boehm, Detlef, Biskup, Saskia, Perner, Sven

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A new bright-field dual-colour chromogenic and silver in situ hybridization method for the detection of FGFR1 gene copy number status von Boehm, Diana, Vogel, Wenzel, Franzen, Alina, Schrock, Andreas, Bootz, Friedrich, Heaseley, Lynn E., Braun, Martin, Perner, Sven

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Landscape of chromosome number changes in prostate cancer progression von Braun, Martin, Stomper, Julia, Kirsten, Robert, Adler, David, Vogel, Wenzel, Böhm, Diana, Wernert, Nicolas, Kristiansen, Glen, Perner, Sven

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