PAI-1–regulated extracellular proteolysis governs senescence and survival in Klotho mice von Eren, Mesut, Boe, Amanda E., Murphy, Sheila B., Place, Aaron T., Nagpal, Varun, Morales-Nebreda, Luisa, Urich, Daniela, Quaggin, Susan E., Budinger, G. R. Scott, Mutlu, Gökhan M., Miyata, Toshio, Vaughan, Douglas E.

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Plasminogen Activator Inhibitor-1 Antagonist TM5441 Attenuates Nω-Nitro-L-Arginine Methyl Ester–Induced Hypertension and Vascular Senescence von Boe, Amanda E, Eren, Mesut, Murphy, Sheila B, Kamide, Christine E, Ichimura, Atsuhiko, Terry, David, McAnally, Danielle, Smith, Layton H, Miyata, Toshio, Vaughan, Douglas E

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Nitric oxide prevents alveolar senescence and emphysema in a mouse model von Boe, Amanda E, Eren, Mesut, Morales-Nebreda, Luisa, Murphy, Sheila B, Budinger, G R Scott, Mutlu, Gökhan M, Miyata, Toshio, Vaughan, Douglas E

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DATA FROM A DIGITAL INHALER COUPLED WITH EXPERT-CONSENSUS RELIEVER MEDICATION USE THRESHOLDS: A NOVEL WAY TO IDENTIFY IMPENDING OR ONGOING ASTHMA EXACERBATION von LUGOGO, NJIRA L, DERSTINE, BRIAN, MOHAN, ARJUN, BOE, AMANDA, BROWN, RANDALL, HILL, TANISHA D, SAFIOTI, GUILHERME G

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Pathways of Escalation to Asthma Biologics in Real-world Clinical Practice: an Analysis of US Claims Data von Brown, Randall, Bender, Bruce, Boe, Amanda, Casciano, Julian, Dotiwala, Zenobia, Herrera, Ernesto Mayen

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DEVELOPMENT OF A NOVEL DASHBOARD UTILIZING DIGITAL INHALER DATA TO SUPPORT CLINICAL MANAGEMENT von LUGOGO, NJIRA L, DERSTINE, BRIAN, GULATI, MEHAK, MOHAN, ARJUN, SENN, REBECCA, HARWOOD, HANNAH, HILL, TANISHA D, BOE, AMANDA, RUTLAND, CEDRIC, SULLIVAN, JUNE, SAFIOTI, GUILHERME G

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NOVEL INSIGHTS GAINED FROM AN INTEGRATED ELECTRONIC INHALER IN PATIENTS WITH SEVERE ASTHMA TREATED WITH BIOLOGICS von MOHAN, ARJUN, DERSTINE, BRIAN A, WANG, STEWART C, SULLIVAN, JUNE, ZHANG, PENG, HARWOOD, HANNAH, MERCHEN, EMILY, ROMANEK, RACHEL, SHOEMAKER, ELAINA, HILL, TANISHA D, BOE, AMANDA, LUGOGO, NJIRA L

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Implementation of a Novel Digital Inhaler Technology in Real-World Clinical Practice: Experiences and Recommendations from Early Adopters von Bansal, Priya, Mosnaim, Giselle, Bajowala, Sakina, Jiang, Yihui, Schafer, Ewa, Skolnik, Neil, Sumino, Kaharu, Vega, Charles, Williams, Paul, Yawn, Barbara, Drummond, Bradley, Anatchkova, Milena, Walsh, Marissa, Boe, Amanda, Hill, Tanisha

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Use of Theory-Based Implementation Research to Evaluate Barriers and Facilitators to Implementation of a Novel Digital Inhaler Technology in Clinical Practice von Schafer, Ewa, Mosnaim, Giselle, Bajowala, Sakina, Bansal, Priya, Jiang, Yihui, Skolnik, Neil, Sumino, Kaharu, Vega, Charles, Williams, Paul, Yawn, Barbara, Drummond, Bradley, Anatchkova, Milena, Walsh, Marissa, Boe, Amanda, Hill, Tanisha

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Assessment of Real-World Escalation to Biologics in US Patients With Asthma von Bender, Bruce, Oppenheimer, John, George, Maureen, Brown, Randall, Patel, Ayush, Hill, Tanisha, Boe, Amanda, Mayen Herrera, Ernesto, Dotiwala, Zenobia, Casciano, Julian, Bernstein, Jonathan A.

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Abstract 69: Angiotensin II- Canonical TGF-β Signaling Downregulates Apelinergic Pathway in Hypertension von Rai, Rahul, Nagpal, Varun, Boe, Amanda E, Vaughan, Douglas E

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The PAI-1 Antagonist TM5441 Attenuates L-NAME-Induced Hypertension and Vascular Senescence von Boe, Amanda E., Eren, Mesut, Murphy, Sheila B., Kamide, Christine E., Ichimura, Atsuhiko, Terry, David, McAnally, Danielle, Smith, Layton H., Miyata, Toshio, Vaughan, Douglas E.

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Nitric Oxide Prevents Alveolar Senescence and Emphysema in a Mouse Model von Boe, Amanda E, Eren, Mesut, Morales-Nebreda, Luisa, Murphy, Sheila B, Budinger, G. R. Scott, Mutlu, Gökhan M, Miyata, Toshio, Vaughan, Douglas E

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Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function von Raleigh, David R, Boe, Devin M, Yu, Dan, Weber, Christopher R, Marchiando, Amanda M, Bradford, Emily M, Wang, Yingmin, Wu, Licheng, Schneeberger, Eveline E, Shen, Le, Turner, Jerrold R

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Exome Sequencing for Prenatal Diagnosis in Nonimmune Hydrops Fetalis von Sparks, Teresa N, Lianoglou, Billie R, Adami, Rebecca R, Pluym, Ilina D, Holliman, Kerry, Duffy, Jennifer, Downum, Sarah L, Patel, Sachi, Faubel, Amanda, Boe, Nina M, Field, Nancy T, Murphy, Aisling, Laurent, Louise C, Jolley, Jennifer, Uy, Cherry, Slavotinek, Anne M, Devine, Patrick, Hodoglugil, Ugur, Van Ziffle, Jessica, Sanders, Stephan J, MacKenzie, Tippi C, Norton, Mary E

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Correlation between early dynamics in circulating tumour DNA and outcome from FOLFIRI treatment in metastatic colorectal cancer von Lyskjær, Iben, Kronborg, Camilla Skovhus, Rasmussen, Mads Heilskov, Sørensen, Boe Sandahl, Demuth, Christina, Rosenkilde, Mona, Johansen, Amanda Frydendahl Boll, Knudsen, Michael, Vang, Søren, Krag, Søren Rasmus Palmelund, Spindler, Karen-Lise Garm, Andersen, Claus Lindbjerg

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Effects of increased scrotal temperature on semen quality and seminal plasma proteins in Brahman bulls von Boe‐Hansen, Gry Brandt, Rêgo, João Paulo A., Satake, Nana, Venus, Bronwyn, Sadowski, Pawel, Nouwens, Amanda, Li, Yutao, McGowan, Michael

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Performance of a concurrent cognitive task modifies pre- and post-perturbation evoked cortical activity von Mochizuki, George, Boe, Shaun G, Marlin, Amanda, McIlroy, William E

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The Global Alliance for Chronic Diseases researchers’ statement on non-communicable disease research with Indigenous peoples von Meharg, David P, Naanyu, Violet, Rambaldini, Boe, Clarke, Marilyn J, Lacey, Cameron, Jebasingh, Felix, Lopez-Jaramillo, Patricio, Gould, Gillian S, Aceves, Benjamin, Alison, Jennifer A, Chaiton, Michael, Chen, Jun, Gonzalez-Salazar, Francisco, Goodyear-Smith, Felicity, Gwynne, Kylie G, Lee, Kylie S, MacKay, Diana, Maple-Brown, Louise, Mishara, Brian L, Nigenda, Gustavo, Ramani-Chander, Anusha, Sherwood, Stephen G, Thomas, Nihal, Thrift, Amanda G, Anderson, Michael

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Risk of chemotherapy-induced febrile neutropenia in patients with metastatic cancer not receiving granulocyte colony-stimulating factor prophylaxis in US clinical practice von Averin, Ahuva, Silvia, Amanda, Lamerato, Lois, Richert-Boe, Kathryn, Kaur, Manpreet, Sundaresan, Devi, Shah, Neel, Hatfield, Mark, Lawrence, Tatiana, Lyman, Gary H., Weycker, Derek

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