Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset von Seashore-Ludlow, Brinton, Rees, Matthew G, Cheah, Jaime H, Cokol, Murat, Price, Edmund V, Coletti, Matthew E, Jones, Victor, Bodycombe, Nicole E, Soule, Christian K, Gould, Joshua, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Wawer, Mathias J, Kuru, Nurdan, Kotz, Joanne D, Hon, C Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Bittker, Joshua A, Palmer, Michelle, Bradner, James E, Shamji, Alykhan F, Clemons, Paul A, Schreiber, Stuart L

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An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules von Basu, Amrita, Bodycombe, Nicole E., Cheah, Jaime H., Price, Edmund V., Liu, Ke, Schaefer, Giannina I., Ebright, Richard Y., Stewart, Michelle L., Ito, Daisuke, Wang, Stephanie, Bracha, Abigail L., Liefeld, Ted, Wawer, Mathias, Gilbert, Joshua C., Wilson, Andrew J., Stransky, Nicolas, Kryukov, Gregory V., Dancik, Vlado, Barretina, Jordi, Garraway, Levi A., Hon, C. Suk-Yee, Munoz, Benito, Bittker, Joshua A., Stockwell, Brent R., Khabele, Dineo, Stern, Andrew M., Clemons, Paul A., Shamji, Alykhan F., Schreiber, Stuart L.

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Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles von Clemons, Paul A., Bodycombe, Nicole E., Carrinski, Hyman A., Wilson, J. Anthony, Shamji, Alykhan F., Wagner, Bridget K., Koehler, Angela N., Schreiber, Stuart L.

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A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay von Bray, Mark-Anthony, Gustafsdottir, Sigrun M, Rohban, Mohammad H, Singh, Shantanu, Ljosa, Vebjorn, Sokolnicki, Katherine L, Bittker, Joshua A, Bodycombe, Nicole E, Dančík, Vlado, Hasaka, Thomas P, Hon, Cindy S, Kemp, Melissa M, Li, Kejie, Walpita, Deepika, Wawer, Mathias J, Golub, Todd R, Schreiber, Stuart L, Clemons, Paul A, Shamji, Alykhan F, Carpenter, Anne E

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Correlating chemical sensitivity and basal gene expression reveals mechanism of action von Rees, Matthew G, Seashore-Ludlow, Brinton, Cheah, Jaime H, Adams, Drew J, Price, Edmund V, Gill, Shubhroz, Javaid, Sarah, Coletti, Matthew E, Jones, Victor L, Bodycombe, Nicole E, Soule, Christian K, Alexander, Benjamin, Li, Ava, Montgomery, Philip, Kotz, Joanne D, Hon, C Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Haber, Daniel A, Clish, Clary B, Bittker, Joshua A, Palmer, Michelle, Wagner, Bridget K, Clemons, Paul A, Shamji, Alykhan F, Schreiber, Stuart L

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Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling von Wawer, Mathias J., Li, Kejie, Gustafsdottir, Sigrun M., Ljos, Vebjorn, Bodycombe, Nicole E., Marton, Melissa A., Sokolnicki, Katherine L., Bray, Mark-Anthony, Kemp, Melissa M., Winchester, Ellen, Taylor, Bradley, Grant, George B., Hon, C. Suk-Yee, Duvall, Jeremy R., Wilson, J. Anthony, Bittker, Joshua A., Dančík, Vlado, Narayan, Rajiv, Subramanian, Aravind, Winckler, Wendy, Golub, Todd R., Carpenter, Anne E., Shamji, Alykhan F., Schreiber, Stuart L., Clemons, Paul A.

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ChemBank: a small-molecule screening and cheminformatics resource database von Seiler, Kathleen Petri, George, Gregory A, Happ, Mary Pat, Bodycombe, Nicole E, Carrinski, Hyman A, Norton, Stephanie, Brudz, Steve, Sullivan, John P, Muhlich, Jeremy, Serrano, Martin, Ferraiolo, Paul, Tolliday, Nicola J, Schreiber, Stuart L., Clemons, Paul A

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A flow cytometry-based screen identifies MBNL1 modulators that rescue splicing defects in myotonic dystrophy type I von Zhang, Fan, Bodycombe, Nicole E, Haskell, Keith M, Sun, Yumei L, Wang, Eric T, Morris, Carl A, Jones, Lyn H, Wood, Lauren D, Pletcher, Mathew T

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A Small-Molecule Screening Strategy To Identify Suppressors of Statin Myopathy von Wagner, Bridget K, Gilbert, Tamara J, Hanai, Jun-ichi, Imamura, Shintaro, Bodycombe, Nicole E, Bon, Robin S, Waldmann, Herbert, Clemons, Paul A, Sukhatme, Vikas P, Mootha, Vamsi K

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Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses von Dančík, Vlado, Carrel, Hyman, Bodycombe, Nicole E., Seiler, Kathleen Petri, Fomina-Yadlin, Dina, Kubicek, Stefan T., Hartwell, Kimberly, Shamji, Alykhan F., Wagner, Bridget K., Clemons, Paul A.

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Enhancing the rate of scaffold discovery with diversity-oriented prioritization von Swamidass, S. Joshua, Calhoun, Bradley T., Bittker, Joshua A., Bodycombe, Nicole E., Clemons, Paul A.

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Small-Molecule Suppressors of Cytokine-Induced β-Cell Apoptosis von Chou, Danny Hung-Chieh, Bodycombe, Nicole E., Carrinski, Hyman A., Lewis, Timothy A., Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K.

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Utility-Aware Screening with Clique-Oriented Prioritization von Swamidass, S. Joshua, Calhoun, Bradley T, Bittker, Joshua A, Bodycombe, Nicole E, Clemons, Paul A

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An Economic Framework to Prioritize Confirmatory Tests after a High-Throughput Screen von Swamidass, S. Joshua, Bittker, Joshua A., Bodycombe, Nicole E., Ryder, Sean P., Clemons, Paul A.

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An Interactive Resource to Identify Cancer Genetic and Lineage Dependencies Targeted by Small Molecules von Basu, Amrita, Bodycombe, Nicole E, Cheah, Jaime H, Price, Edmund V, Liu, Ke, Schaefer, Giannina Ines, Ebright, Richard Yon, Stewart, Michelle L, Ito, Daisuke, Wang, Stephanie, Bracha, Abigail L, Liefeld, Ted, Wawer, Mathias, Gilbert, Joshua C, Wilson, Andrew J, Stransky, Nicolas, Kryukov, Gregory V, Dancik, Vlado, Barretina, Jordi, Garraway, Levi Alexander, Hon, C. Suk-Yee, Munoz, Benito, Bittker, Joshua A, Stockwell, Brent R, Khabele, Dineo, Stern, Andrew M, Clemons, Paul A, Shamji, Alykhan F, Schreiber, Stuart L

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ChemBank: A Small-Molecule Screening and Cheminformatics Resource Database von Seiler, Kathleen Petri, George, Gregory A, Happ, Mary Pat, Bodycombe, Nicole E, Carrinski, Hyman A, Norton, Stephanie, Brudz, Steve, Serrano, Martin, Ferraiolo, Paul, Tolliday, Nicola J, Clemons, Paul A, Sullivan, John P, Muhlich, Jeremy, Schreiber, Stuart L

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CIL:46269, Homo sapiens. In Cell Image Library von Gustafsdottir, Sigrun, Ljosa, Vebjorn, Sokolnicki, Katherine, Bittker, Joshua, Bodycombe, Nicole E., Bray, Mark, Dancik, Vlado, Hasaka, Tom, Hon, Suk, Kemp, Melissa, Li, Kejie, Walpita, Deepika, Wawer, Mathias, Golub, Todd R., Schreiber, Stuart, Clemons, Paul, Carpenter, Anne, Shamji, Alykhan

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CIL:46259, Homo sapiens. In Cell Image Library von Gustafsdottir, Sigrun, Ljosa, Vebjorn, Sokolnicki, Katherine, Bittker, Joshua, Bodycombe, Nicole E., Bray, Mark, Dancik, Vlado, Hasaka, Tom, Hon, Suk, Kemp, Melissa, Li, Kejie, Walpita, Deepika, Wawer, Mathias, Golub, Todd R., Schreiber, Stuart, Clemons, Paul, Carpenter, Anne, Shamji, Alykhan

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CIL:45793, Homo sapiens. In Cell Image Library von Gustafsdottir, Sigrun, Ljosa, Vebjorn, Sokolnicki, Katherine, Bittker, Joshua, Bodycombe, Nicole E., Bray, Mark, Dancik, Vlado, Hasaka, Tom, Hon, Suk, Kemp, Melissa, Li, Kejie, Walpita, Deepika, Wawer, Mathias, Golub, Todd R., Schreiber, Stuart, Clemons, Paul, Carpenter, Anne, Shamji, Alykhan

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CIL:45889, Homo sapiens. In Cell Image Library von Gustafsdottir, Sigrun, Ljosa, Vebjorn, Sokolnicki, Katherine, Bittker, Joshua, Bodycombe, Nicole E., Bray, Mark, Dancik, Vlado, Hasaka, Tom, Hon, Suk, Kemp, Melissa, Li, Kejie, Walpita, Deepika, Wawer, Mathias, Golub, Todd R., Schreiber, Stuart, Clemons, Paul, Carpenter, Anne, Shamji, Alykhan

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