Case series of patients with severe sickle cell disease treated with voxelotor (GBT440) by compassionate access von Blyden, Gershwin, Bridges, Kenneth R., Bronte, Lanetta

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A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease von Vichinsky, Elliott, Hoppe, Carolyn C, Ataga, Kenneth I, Ware, Russell E, Nduba, Videlis, El-Beshlawy, Amal, Hassab, Hoda, Achebe, Maureen M, Alkindi, Salam, Brown, R. Clark, Diuguid, David L, Telfer, Paul, Tsitsikas, Dimitris A, Elghandour, Ashraf, Gordeuk, Victor R, Kanter, Julie, Abboud, Miguel R, Lehrer-Graiwer, Joshua, Tonda, Margaret, Intondi, Allison, Tong, Barbara, Howard, Jo

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A Single Center Experience of GBT440 Treatment of Severe Anemia in Sickle Cell Disease (SCD) von Bridges, Kenneth R., Gershwin, Blyden, Bronte, Lanetta

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Assessment of Biomarker Response to Clinical Administration of Adakveo in a “Real World” Clinical Setting: A Model for Therapeutic Monitoring in Sickle Cell Disease (SCD) von White, Jennell, Packer-Pencle, Corrine, Gao, Xiufeng, Williams-Montgomery, Andrekia, Blyden, Gershwin Theophilus, Bronté-Hall, Lanetta, Hines, Patrick C.

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Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling... von Kuo, Kevin H.M., Singer, Sylvia Titi, Blyden, Gershwin Theophilus, Bronté-Hall, Lanetta, Faller, Aidan, Kutlar, Abdullah, Kuypers, Frans A., Zaidi, Aliya U., Hines, Patrick C., Patel, Niren, Larkin, Sandra, Al-Samkari, Hanny, Sheth, Sujit, Nouraie, Seyed Mehdi, Perrine, Susan

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Treatment with IMR-687, a Highly Selective PDE9 Inhibitor, Increases HbF and Reduces VOCs in Adults with Sickle Cell Disease in a Long-Term, Phase 2a, Open-Label Extension Study von Andemariam, Biree, Mant, Timothy, Eleftheriou, Perla, Lugthart, Sanne, Bronté-Hall, Lanetta, Barroso, Filipa, Blyden, Gershwin, Mason, James, Barysauskas, Constance M, Yen, Joseph, Tang, Karen, Ballal, Rahul, Attie, Kenneth

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Benefits and Safety of Long-Term Use of IMR-687 As Monotherapy or in Combination with a Stable Dose of Hydroxyurea (HU) in 2 Adult Sickle Cell Patients von Bronte-Hall, Lanetta, Andemariam, Biree, Gershwin, Blyden, Lugthart, Sanne, Mant, Timothy, Howard, Jo, Fok, Henry, Eleftheriou, Perla, Hagar, Robert Ward, Mason, James, Ballal, Rahul, Lufkin, Joelle, Lisbon, Eleanor

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Primary Analysis of Spartan: A Phase 2 Trial to Assess the Efficacy and Safety of Crizanlizumab in Patients with Sickle Cell Disease Related Priapism von Idowu, Modupe, DeBaun, Michael R., Burnett, Arthur, Darbari, Deepika S., Adam, Soheir, Anderson, Alan Randall, Kanter, Julie, Billett, Henny H., Liles, Darla K., Nickel, Robert S., Decastro, Laura M., Andemariam, Biree, Blyden, Gershwin Theophilus, Heeney, Matthew M., Ramadas, Poornima, McLemore, Morgan L., Kolekar, Yogita, Laine, Dramane, Paulose, Jincy, Sarkar, Rajendra, Vignogna, Mary Beth, El Rassi, Fuad

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Real-World Clinical Burden of Sickle Cell Disease in the US Community-Practice Setting: A Single-Center Experience from the Foundation for Sickle Cell Disease Research von Bronté-Hall, Lanetta, Parkin, Matthew, Green, Courtney, Tchouambou, Elsa, Huynh, Lynn, Puri-Sharma, Charu, Chang, Rose, Chawla, Anjulika, Signorovitch, James, Blyden, Gershwin Theophilus

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The Benefits Trial of PB-04 to Evaluate Safety, PK, and Preliminary Efficacy in Inducing Fetal Globin Expression in Beta Thalassemia Intermedia and Sickle Cell Disease von Kuo, Kevin H.M., Singer, Sylvia, Sheth, Sujit, Al-Samkari, Hanny, Blyden, Gershwin, Bronte-Hall, Lanetta, Pace, Betty S., Kutlar, Abdullah, Kuypers, Franciscus A., Faller, Aidan D, Nouraie, Seyed Mehdi, Terse, Pramod, Jin, Haksong, Xu, Xin, Alimardanov, Asaf, Sytkowski, Arthur J., Haugabook, Sharie, Perrine, Susan P

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Pharmacokinetics of Diphenhydramine and a Demethylated Metabolite Following Intravenous And Oral Administration von Blyden, Gershwin T., Greenblatt, David J., Scavone, Joseph M., Shader, Richard I.

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Effect of cyclosporin A on rat kidney catecholamines von Duruibe, Valentine A., Okonmah, Anthony, Panton, Lloyd, Blyden, Gershwin T.

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Uptake of atrial natriuretic peptide and production of cGMP in cultured human glomerular endothelial cells von Green, D F, Duruibe, V A, Blyden, G, Laskey, R E, Bourgoignie, J J

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Metronidazole Impairs Clearance of Phenytoin but Not of Alprazolam or Lorazepam von Blyden, Gershwin T., Scavone, Joseph M., Greenblatt, David J.

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Lack of effect of influenza vaccine on the pharmacokinetics of antipyrine, alprazolam, paracetamol (acetaminophen) and lorazepam von SCAVONE, J. M, BLYDEN, G. T, GREENBLATT, D. J

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Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines von Lachman, Lawrence B., Hacker, Miles P., Blyden, Gershwin T., Handschumacher, Robert E.

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Antipyrine Pharmacokinetics in Women Receiving Conjugated Estrogens von Scavone, Joseph M., Greenblatt, David J., Blyden, Gershwin T.

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Validity of a two-point acetaminophen pharmacokinetic study von SCAVONE, J. M, GREENBLATT, D. J, BLYDEN, G. T, LUNA, B. G, HARMATZ, J. S

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Cyclosporine Blood Concentrations Determined by Specific Versus Nonspecific Assay Methods von Blyden, Gershwin T., Franklin, Cass, Cho, Sang I., Kaplan, Marshall M., Hirsch, Carl A., Greenblatt, David J.

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Intracardiac tumor regression documented by two-dimensional echocardiography von Wiske, Prescott S., Gillam, Linda D., Blyden, Gershwin, Weyman, Arthur E.

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