Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors von Muik, Alexander, Garralda, Elena, Altintas, Isil, Gieseke, Friederike, Geva, Ravit, Ben-Ami, Eytan, Maurice-Dror, Corinne, Calvo, Emiliano, LoRusso, Patricia M, Alonso, Guzman, Rodriguez-Ruiz, Maria E, Schoedel, Kristina B, Blum, Jordan M, Sänger, Bianca, Salcedo, Theodora W, Burm, Saskia M, Stanganello, Eliana, Verzijl, Dennis, Vascotto, Fulvia, Sette, Angelica, Quinkhardt, Juliane, Plantinga, Theo S, Toker, Aras, van den Brink, Edward N, Fereshteh, Mark, Diken, Mustafa, Satijn, David, Kreiter, Sebastian, Breij, Esther C W, Bajaj, Gaurav, Lagkadinou, Eleni, Sasser, Kate, Türeci, Özlem, Forssmann, Ulf, Ahmadi, Tahamtan, Şahin, Uğur, Jure-Kunkel, Maria, Melero, Ignacio

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Distinct and Overlapping Sarcoma Subtypes Initiated from Muscle Stem and Progenitor Cells von Blum, Jordan M., Añó, Leonor, Li, Zhizhong, Van Mater, David, Bennett, Brian D., Sachdeva, Mohit, Lagutina, Irina, Zhang, Minsi, Mito, Jeffrey K., Dodd, Leslie G., Cardona, Diana M., Dodd, Rebecca D., Williams, Nerissa, Ma, Yan, Lepper, Christoph, Linardic, Corinne M., Mukherjee, Sayan, Grosveld, Gerard C., Fan, Chen-Ming, Kirsch, David G.

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Critical role of kinase activity of hematopoietic progenitor kinase 1 in anti-tumor immune surveillance von Liu, Jinqi, Curtin, Joshua, You, Dan, Hillerman, Stephen, Li-Wang, Bifang, Eraslan, Rukiye, Xie, Jenny, Swanson, Jesse, Ho, Ching-Ping, Oppenheimer, Simone, Warrack, Bethanne M, McNaney, Colleen A, Nelson, David M, Blum, Jordan, Kim, Taeg, Fereshteh, Mark, Reily, Michael, Shipkova, Petia, Murtaza, Anwar, Sanjuan, Miguel, Hunt, John T, Salter-Cid, Luisa

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Imaging hematopoietic precursor division in real time von Wu, Mingfu, Kwon, Hyog Young, Rattis, Frederique, Blum, Jordan, Zhao, Chen, Ashkenazi, Rina, Jackson, Trachette L, Gaiano, Nicholas, Oliver, Tim, Reya, Tannishtha

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DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity von Muik, Alexander, Adams III, Homer C, Gieseke, Friederike, Altintas, Isil, Schoedel, Kristina B, Blum, Jordan M, Sänger, Bianca, Burm, Saskia M, Stanganello, Eliana, Verzijl, Dennis, Spires, Vanessa M, Vascotto, Fulvia, Toker, Aras, Quinkhardt, Juliane, Fereshteh, Mark, Diken, Mustafa, Satijn, David P E, Kreiter, Sebastian, Ahmadi, Tahamtan, Breij, Esther C W, Türeci, Özlem, Sasser, Kate, Sahin, Ugur, Jure-Kunkel, Maria

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Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma von Lee, Chang-Lung, Castle, Katherine D., Moding, Everett J., Blum, Jordan M., Williams, Nerissa, Luo, Lixia, Ma, Yan, Borst, Luke B., Kim, Yongbaek, Kirsch, David G.

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Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway von Van Mater, David, Añó, Leonor, Blum, Jordan M, Webster, Micah T, Huang, WeiQiao, Williams, Nerissa, Ma, Yan, Cardona, Diana M, Fan, Chen-Ming, Kirsch, David G

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Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis von Lee, Chang-Lung, Blum, Jordan M., Kirsch, David G.

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Breastmilk influences development and composition of the oral microbiome von Butler, Catherine A., Adams, Geoffrey G., Blum, Jordan, Byrne, Samantha J., Carpenter, Lauren, Gussy, Mark G., Calache, Hanny, Catmull, Deanne V., Reynolds, Eric C., Dashper, Stuart G.

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Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer von Fujiwara, Kenji, Saung, May Tun, Jing, Hao, Herbst, Brian, Zarecki, MacKenzie, Muth, Stephen, Wu, Annie, Bigelow, Elaine, Chen, Linda, Li, Keyu, Jurcak, Neolle, Blair, Alex B, Ding, Ding, Wichroski, Michael, Blum, Jordan, Cheadle, Nathan, Koenitzer, Jennifer, Zheng, Lei

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Methods to Generate Genetically Engineered Mouse Models of Soft Tissue Sarcoma von Dodd, Rebecca D., Añó, Leonor, Blum, Jordan M., Li, Zhizhong, Van Mater, David, Kirsch, David G.

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Determinants of Clinical Decision Making under Uncertainty in Dentistry: A Scoping Review von Murdoch, Alexander Ivon King, Blum, Jordan, Chen, Jie, Baziotis-Kalfas, Dean, Dao, Angelie, Bai, Kevin, Bekheet, Marina, Atwal, Nimret, Cho, Sarah Sung Hee, Ganhewa, Mahen, Cirillo, Nicola

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The various forms of tooth resorption von Blum, Jordan Samuel

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813 Combination of HexaBody-CD27 with PD-(L)1 blockade potentiates single-agent activity leading to enhanced human T-cell effector functions in vitro von Imle, Andrea, Altintas, Isil, Nuermberger, Kristina, Blum, Jordan, Krause, Anna-Lena, Toker, Aras, Daszkiewicz, Lidia, Muik, Alexander, Gieseke, Friederike, Ahmadi, Tahamtan, Fellermeier-Kopf, Sina, Kemper, Kristel, Tuereci, Oezlem, Breij, Esther, Sahin, Ugur

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Embryonic Signaling Pathways and Rhabdomyosarcoma: Contributions to Cancer Development and Opportunities for Therapeutic Targeting von Kirsch, David G., Blum, Jordan, Kephart, Julie Grondin, Belyea, Brian, Linardic, Corinne M.

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238 Molecular dissection of tumor-immune microenvironment factors associated with response to checkpoint inhibitor therapy in non-small cell lung cancer patients using nanostring d... von Jabado, Omar, Couto, Suzana, Blum, Jordan, Franken, Patrick, Souza, Patricia Coutinho de, Jure-Kunkel, Maria, Pencheva, Nora, Higgs, Brandon, Sasser, Kate, Fereshteh, Mark

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Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia von Zhao, Chen, Chen, Alan, Jamieson, Catriona H., Fereshteh, Mark, Abrahamsson, Annelie, Blum, Jordan, Kwon, Hyog Young, Kim, Jynho, Chute, John P., Rizzieri, David, Munchhof, Michael, VanArsdale, Todd, Beachy, Philip A., Reya, Tannishtha

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Loss of β-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo von Zhao, Chen, Blum, Jordan, Chen, Alan, Kwon, Hyog Young, Jung, Seung Hye, Cook, J. Michael, Lagoo, Anand, Reya, Tannishtha

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Regulation of myeloid leukaemia by the cell-fate determinant Musashi von Ito, Takahiro, Kwon, Hyog Young, Zimdahl, Bryan, Congdon, Kendra L., Blum, Jordan, Lento, William E., Zhao, Chen, Lagoo, Anand, Gerrard, Gareth, Foroni, Letizia, Goldman, John, Goh, Harriet, Kim, Soo-Hyun, Kim, Dong-Wook, Chuah, Charles, Oehler, Vivian G., Radich, Jerald P., Jordan, Craig T., Reya, Tannishtha

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Deep Peripheral T Cell Immune-Profiling in Relapsed/Refractory Non-Hodgkin Lymphoma: Evaluation of Baseline Samples from the Epcoritamab Epcore NHL-1 Trial von Blum, Jordan, Masters, Gregg, Chiu, Christopher, Si, Han, Gale, Jeremy, Grimm, Lisa, Ma-Edmonds, Manling, Loya, Matthew, Bachu, Mahesh, Jabado, Omar, Soong, David, Zhang, Jimin, Wielgos-Bonvallet, Monica, Bottrel, Nicole, Henitz, Erin, Higgs, Brandon, Sasser, Kate, Jure-Kunkel, Maria, Fereshteh, Mark

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