Pharmacological discrimination of GluR5 and GluR6 kainate receptor subtypes by (3S,4aR,6R,8aR)-6-[2-(1(2)H-tetrazole-5-yl)ethyl]decahyd roisdoquinoline-3 carboxylic-acid von Bleakman, R, Schoepp, D D, Ballyk, B, Bufton, H, Sharpe, E F, Thomas, K, Ornstein, P L, Kamboj, R K

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Efficacy and safety of ixekizumab in a randomized, double‐blinded, placebo‐controlled phase IIIb study of patients with moderate‐to‐severe genital psoriasis von Ryan, C., Menter, A., Guenther, L., Blauvelt, A., Bissonnette, R., Meeuwis, K., Sullivan, J., Cather, J.C., Yosipovitch, G., Gottlieb, A.B., Merola, J.F., Callis Duffin, K., Fretzin, S., Osuntokun, O.O., Burge, R., Naegeli, A.N., Yang, F.E., Lin, C.‐Y., Todd, K., Potts Bleakman, A.

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Ixekizumab Results in Persistent Clinical Improvement in Moderate-to-Severe Genital Psoriasis During a 52 Week, Randomized, Placebo-Controlled, Phase 3 Clinical Trial von Guenther, Lyn, Potts Bleakman, Alison, Weisman, Jamie, Poulin, Yves, Spelman, Lynda, Burge, Russel, Erickson, Janelle, Todd, Kristin, Bertram, Clinton C., Ryan, Caitriona

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Pharmacological agents von D. BLEAKMAN,D. R. HELTON, D.LODGE

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Impact of ixekizumab on facial psoriasis and related quality of life measures in moderate‐to‐severe psoriasis patients: 12‐week results from two phase III trials von Paul, C., Guenther, L., Torii, H., Sofen, H., Burge, R., Lin, C.Y., Potts Bleakman, A., Mallbris, L., Poulin, Y.

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Impact of ixekizumab treatment on skin‐related personal relationship difficulties in moderate‐to‐severe psoriasis patients: 12‐week results from two Phase 3 trials von Guenther, L., Warren, R.B., Cather, J.C., Sofen, H., Poulin, Y., Lebwohl, M., Terui, T., Potts Bleakman, A., Zhu, B., Burge, R., Reich, K., Kerkhof, P.

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The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic... von Thompson, Karen J., Watson, Sonia, Zanato, Chiara, Dall'Angelo, Sergio, De Nooij, Joriene C., Pace‐Bonello, Bethany, Shenton, Fiona C., Sanger, Helen E., Heinz, Beverly A., Broad, Lisa M., Grosjean, Noelle, McQuillian, Jessica R., Dubini, Marina, Pyner, Susan, Greig, Iain, Zanda, Matteo, Bleakman, David, Banks, Robert W., Bewick, Guy S.

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Ixekizumab improves secondary lesional signs, pain and sexual health in patients with moderate‐to‐severe genital psoriasis von Merola, J.F., Ghislain, P.‐D., Dauendorffer, J.N., Potts Bleakman, A., Brnabic, A.J.M., Burge, R., Riedl, E.

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P759 Understanding how patients with moderate-to-severe Crohn’s disease describe the spectrum of bowel urgency definitions: Results from qualitative research von Dubinsky, M C, Hunter Gibble, T, Stassek, L, Harding, G, Stefan, M, Fikre, T, Potts Bleakman, A, Moses, R

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A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus von Lauri, Sari E, Bortolotto, Zuner A, Nistico, Robert, Bleakman, David, Ornstein, Paul L, Lodge, David, Isaac, John T R, Collingridge, Graham L

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Imaging Drugs with and without Clinical Analgesic Efficacy von UPADHYAY, Jaymin, ANDERSON, Julie, NENI, Saujanya, MAIER, Gary, IYENGAR, Smriti, EVELHOCH, Jeffery L, BLEAKMAN, David, HARGREAVES, Richard, BECERRA, Lino, BORSOOK, David, SCHWARZ, Adam J, COIMBRA, Alexandre, BAUMGARTNER, Richard, PENDSE, G, GEORGE, Edward, NUTILE, Lauren, WALLIN, Diana, BISHOP, James

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DOP70 Prevalence and severity of bowel urgency in Crohn’s Disease: Results from the Communicating Needs and Features of IBD Experience (CONFIDE) Survey von Dubinsky, M C, Gibble, T, Travis, S, Panaccione, R, Hibi, T, Bleakman, A P, Panni, T, Kayhan, C, Favia, A D, Atkinson, C, Schreiber, S, Rubin, D T

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P285 Communicating Needs and Features of IBD Experiences (CONFIDE) Survey: European and US Patient and Health Care Professional Perspectives on the Broad Impact of Bowel Urgency in... von Travis, S, Potts Bleakman, A, Panni, T, Schreiber, S, Dubinsky, M, Panaccione, R, Hibi, T, Kayhan, C, Hunter Gibble, T, Flynn, E, Atkinson, C, Rubin, D T

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Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine von Upadhyay, Jaymin, Anderson, Julie, Baumgartner, Richard, Coimbra, Alexandre, Schwarz, Adam J., Pendse, Gautam, Wallin, Diana, Nutile, Lauren, Bishop, James, George, Edward, Elman, Igor, Sunkaraneni, Soujanya, Maier, Gary, Iyengar, Smriti, Evelhoch, Jeffrey L., Bleakman, David, Hargreaves, Richard, Becerra, Lino, Borsook, David

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Ixekizumab efficacy and safety in moderate‐to‐severe genital psoriasis von Ryan, C., Menter, A., Guenther, L., Blauvelt, A., Bissonnette, R., Meeuwis, K., Sullivan, J., Cather, J.C., Yosipovitch, G., Gottlieb, A.B., Merola, J.F., Callis Duffin, K., Fretzin, S., Osuntokun, O.O., Burge, R., Naegeli, A.N., Yang, F.E., Lin, C.‐Y., Todd, K., Potts Bleakman, A.

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P507 United States and European patient perspectives on the impact of moderate-to-severe Ulcerative Colitis on sexual activity: Communicating Needs and Features of IBD Experiences... von Travis, S, Bleakman, A, Dubinsky, M, Rubin, D, Panaccione, R, Hibi, T, Kayhan, C, Gibble, T H, Sapin, C, Flynn, E, Atkinson, C, Schreiber, S

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Kainate receptors are involved in synaptic plasticity von Collingridge, Graham L, Bortolotto, Zuner A, Clarke, Vernon R. J, Delany, Caroline M, Parry, Michael C, Smolders, Ilse, Vignes, Michel, Ho, Ken H, Miu, Peter, Brinton, Bradford T, Fantaske, Robert, Ogden, Ann, Gates, Mary, Ornstein, Paul L, Lodge, David, Bleakman, David

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012 Efficacy and Safety of Ixekizumab in a Randomized, Double-Blinded, Placebo-Controlled, Phase 3b Clinical Trial in Patients with Moderate-to-Severe Genital Psoriasis von Ryan, C., Menter, A., Guenther, L., Blauvelt, A., Bissonnette, R., Yang, F.E., Potts Bleakman, A.

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A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission von Bleakman, David, Clarke, Vernon R. J, Ballyk, Barbara A, Hoo, Ken H, Mandelzys, Allan, Pellizzari, Andrew, Bath, Catherine P, Thomas, Justyn, Sharpe, Erica F, Davies, Ceri H, Ornstein, Paul L, Schoepp, Darryle D, Kamboj, Rajender K, Collingridge, Graham L, Lodge, David

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Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones von Chard, P S, Bleakman, D, Christakos, S, Fullmer, C S, Miller, R J

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