Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids von Lafrance, Marc, Blaquière, Nicole, Fagnou, Keith

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Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties von Dragovich, Peter S, Pillow, Thomas H, Blake, Robert A, Sadowsky, Jack D, Adaligil, Emel, Adhikari, Pragya, Bhakta, Sunil, Blaquiere, Nicole, Chen, Jinhua, dela Cruz-Chuh, Josefa, Gascoigne, Karen E, Hartman, Steven J, He, Mingtao, Kaufman, Susan, Kleinheinz, Tracy, Kozak, Katherine R, Liu, Liang, Liu, Liling, Liu, Qi, Lu, Ying, Meng, Fanwei, Mulvihill, Melinda M, O’Donohue, Aimee, Rowntree, Rebecca K, Staben, Leanna R, Staben, Steven T, Wai, John, Wang, Jian, Wei, BinQing, Wilson, Catherine, Xin, Jianfeng, Xu, Zijin, Yao, Hui, Zhang, Donglu, Zhang, Hongyan, Zhou, Hao, Zhu, Xiaoyu

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Ruthenium-Catalyzed Dehydrogenation of Ammonia Boranes von Blaquiere, Nicole, Diallo-Garcia, Sarah, Gorelsky, Serge I., Black, Daniel A., Fagnou, Keith

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NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus von Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico

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Aporphine Alkaloid Synthesis and Diversification via Direct Arylation von Lafrance, Marc, Blaquiere, Nicole, Fagnou, Keith

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Medicinal Chemistry of Inhibiting RING-Type E3 Ubiquitin Ligases von Blaquiere, Nicole, Villemure, Elisia, Staben, Steven T

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Monomeric Targeted Protein Degraders von Hanan, Emily J, Liang, Jun, Wang, Xiaojing, Blake, Robert A, Blaquiere, Nicole, Staben, Steven T

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Four-Component Synthesis of Fully Substituted 1,2,4-Triazoles von Staben, Steven T, Blaquiere, Nicole

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Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα) von Dragovich, Peter S., Adhikari, Pragya, Blake, Robert A., Blaquiere, Nicole, Chen, Jinhua, Cheng, Yun-Xing, den Besten, Willem, Han, Jinping, Hartman, Steven J., He, Jintang, He, Mingtao, Rei Ingalla, Ellen, Kamath, Amrita V., Kleinheinz, Tracy, Lai, Tommy, Leipold, Douglas D., Li, Chun Sing, Liu, Qi, Lu, Jiawei, Lu, Ying, Meng, Fanwei, Meng, Lingyao, Ng, Carl, Peng, Kaishan, Lewis Phillips, Gail, Pillow, Thomas H., Rowntree, Rebecca K., Sadowsky, Jack D., Sampath, Deepak, Staben, Leanna, Staben, Steven T., Wai, John, Wan, Kunpeng, Wang, Xinxin, Wei, BinQing, Wertz, Ingrid E., Xin, Jianfeng, Xu, Keyang, Yao, Hui, Zang, Richard, Zhang, Donglu, Zhou, Hao, Zhao, Yongxin

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Discovery of 2‑{3-[2-(1-Isopropyl-3-methyl‑1H‑1,2–4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2‑d][1,4]oxazepin-9-yl]‑1H‑pyrazol-1-yl}-2-methylpropanamide (GDC-0032): A β‑Sparing... von Ndubaku, Chudi O, Heffron, Timothy P, Staben, Steven T, Baumgardner, Matthew, Blaquiere, Nicole, Bradley, Erin, Bull, Richard, Do, Steven, Dotson, Jennafer, Dudley, Danette, Edgar, Kyle A, Friedman, Lori S, Goldsmith, Richard, Heald, Robert A, Kolesnikov, Aleksandr, Lee, Leslie, Lewis, Cristina, Nannini, Michelle, Nonomiya, Jim, Pang, Jodie, Price, Steve, Prior, Wei Wei, Salphati, Laurent, Sideris, Steve, Wallin, Jeffery J, Wang, Lan, Wei, BinQing, Sampath, Deepak, Olivero, Alan G

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Decarboxylative Ketone Aldol Reactions: Development and Mechanistic Evaluation under Metal-Free Conditions von Blaquiere, Nicole, Shore, Daniel G, Rousseaux, Sophie, Fagnou, Keith

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Heteroarylation of Azine N-Oxides von Gosselin, Francis, Savage, Scott J, Blaquiere, Nicole, Staben, Steven T

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Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines von Castanedo, Georgette M, Seng, Pamela S, Blaquiere, Nicole, Trapp, Sean, Staben, Steven T

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Primary Amine Tethered Small Molecules Promote the Degradation of X‑Linked Inhibitor of Apoptosis Protein von Besten, Willem den, Verma, Kshitij, Yamazoe, Sayumi, Blaquiere, Nicole, Phung, Wilson, Izrael-Tomasevic, Anita, Mulvihill, Melinda M, Helgason, Elizabeth, Prakash, Sumit, Goncharov, Tatiana, Vucic, Domagoj, Dueber, Erin, Fairbrother, Wayne J, Wertz, Ingrid, Yu, Kebing, Staben, Steven T

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Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-κB Inducing Kinase von Blaquiere, Nicole, Castanedo, Georgette M, Burch, Jason D, Berezhkovskiy, Leonid M, Brightbill, Hans, Brown, Suzanne, Chan, Connie, Chiang, Po-Chang, Crawford, James J, Dong, Teresa, Fan, Peter, Feng, Jianwen, Ghilardi, Nico, Godemann, Robert, Gogol, Emily, Grabbe, Alice, Hole, Alison J, Hu, Baihua, Hymowitz, Sarah G, Alaoui Ismaili, Moulay Hicham, Le, Hoa, Lee, Patrick, Lee, Wyne, Lin, Xingyu, Liu, Ning, McEwan, Paul A, McKenzie, Brent, Silvestre, Hernani L, Suto, Eric, Sujatha-Bhaskar, Swathi, Wu, Guosheng, Wu, Lawren C, Zhang, Yamin, Zhong, Zoe, Staben, Steven T

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Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncompl... von Taft, Benjamin R, Yokokawa, Fumiaki, Kirrane, Tom, Mata, Anne-Catherine, Huang, Richard, Blaquiere, Nicole, Waldron, Grace, Zou, Bin, Simon, Oliver, Vankadara, Subramanyam, Chan, Wai Ling, Ding, Mei, Sim, Sandra, Straimer, Judith, Guiguemde, Armand, Lakshminarayana, Suresh B, Jain, Jay Prakash, Bodenreider, Christophe, Thompson, Christopher, Lanshoeft, Christian, Shu, Wei, Fang, Eric, Qumber, Jafri, Chan, Katherine, Pei, Luying, Chen, Yen-Liang, Schulz, Hanna, Lim, Jessie, Abas, Siti Nurdiana, Ang, Xiaoman, Liu, Yugang, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Gamo, Francisco Javier, Crespo-Fernandez, Benigno, Rosenthal, Philip J, Cooper, Roland A, Tumwebaze, Patrick, Aguiar, Anna Caroline Campos, Campo, Brice, Campbell, Simon, Wagner, Jürgen, Diagana, Thierry T, Sarko, Christopher

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Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) von Castanedo, Georgette M, Blaquiere, Nicole, Beresini, Maureen, Bravo, Brandon, Brightbill, Hans, Chen, Jacob, Cui, Hai-Feng, Eigenbrot, Charles, Everett, Christine, Feng, Jianwen, Godemann, Robert, Gogol, Emily, Hymowitz, Sarah, Johnson, Adam, Kayagaki, Nobuhiko, Kohli, Pawan Bir, Knüppel, Kathleen, Kraemer, Joachim, Krüger, Susan, Loke, Pui, McEwan, Paul, Montalbetti, Christian, Roberts, David A, Smith, Myron, Steinbacher, Stefan, Sujatha-Bhaskar, Swathi, Takahashi, Ryan, Wang, Xiaolu, Wu, Lawren C, Zhang, Yamin, Staben, Steven T

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Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design von Crawford, James J., Feng, Jianwen, Brightbill, Hans D., Johnson, Adam R., Wright, Matthew, Kolesnikov, Aleksandr, Lee, Wendy, Castanedo, Georgette M., Do, Steven, Blaquiere, Nicole, Staben, Steven T., Chiang, Po-Chang, Fan, Peter W., Baumgardner, Matt, Wong, Susan, Godemann, Robert, Grabbe, Alice, Wiegel, Catharina, Sujatha-Bhaskar, Swathi, Hymowitz, Sarah G., Liau, Nicholas, Hsu, Peter L., McEwan, Paul A., Ismaili, Moulay Hicham Alaoui, Landry, Matthew L.

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Development of a tripartite solvent blend for sustainable chromatographyElectronic supplementary information (ESI) available: General experimental procedure and spectroscopic data.... von Chardon, Florence M, Blaquiere, Nicole, Castanedo, Georgette M, Koenig, Stefan G

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Development of a tripartite solvent blend for sustainable chromatography von Chardon, Florence M, Blaquiere, Nicole, Castanedo, Georgette M, Koenig, Stefan G

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