Genetic Obesity and Bariatric Surgery Outcome in 1014 Patients with Morbid Obesity von Cooiman, M.I., Kleinendorst, L., Aarts, E.O., Janssen, I.M.C., van Amstel, H.K. Ploos, Blakemore, A.I., Hazebroek, E.J., Meijers-Heijboer, H.J., van der Zwaag, B., Berends, F.J., van Haelst, M.M.

Volltext

Polycystic ovary syndrome and leukocyte telomere length: cross-sectional and longitudinal changes von Pölönen, J, Pinola, P, Ronkainen, J, Blakemore, AI, Buxton, JL, Tapanainen, JS, Franks, S, Piltonen, TT, Sebert, S, Morin-Papunen, L

Volltext

Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2... von Ji, Y, Yiorkas, AM, Frau, F, Mook-Kanamori, D, Staiger, H, Thomas, EL, Atabaki-Pasdar, N, Campbell, A, Tyrrell, J, Jones, SE, Beaumont, RN, Wood, AR, Tuke, MA, Ruth, KS, Mahajan, A, Murray, A, Freathy, RM, Weedon, MN, Hattersley, AT, Hayward, C, Machann, J, Haering, H-U, Franks, P, De Mutsert, R, Pearson, E, Stefan, N, Frayling, TM, Allebrandt, KV, Bell, JD, Blakemore, AI, Yaghootkar, H

Volltext

Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease von de Smith, A.J., Walters, R.G., Froguel, P., Blakemore, A.I.

Volltext

PDGFRα demarcates the cardiogenic clonogenic Sca1(+) stem/progenitor cell in adult murine myocardium von Noseda, M, Harada, M, McSweeney, S, Leja, T, Belian, E, Stuckey, DJ, Abreu Paiva, MS, Habib, J, Macaulay, I, De Smith, AJ, Al-Beidh, F, Sampson, R, Lumbers, RT, Rao, P, Harding, SE, Blakemore, AI, Eirik Jacobsen, S, Barahona, M, Schneider, MD

Volltext

Body composition of the host influences dendritic cell phenotype in patients treated for colorectal cancer von Malietzis, G, Lee, GH, Al-Hassi, HO, Bernardo, D, Blakemore, AI, Kennedy, RH, Moorghen, M, Jenkins, JT, Knight, SC

Volltext

Analysis with the exome array identifies multiple new independent variants in lipid loci von Kanoni, S, Masca, NG, Stirrups, KE, Varga, TV, Warren, HR, Scott, RA, Southam, L, Zhang, W, Yaghootkar, H, Müller-Nurasyid, M, Couto Alves, A, Strawbridge, RJ, Lataniotis, L, An Hashim, N, Besse, C, Boland, A, Braund, PS, Connell, JM, Dominiczak, A, Farmaki, AE, Franks, S, Grallert, H, Jansson, JH, Karaleftheri, M, Keinänen-Kiukaanniemi, S, Matchan, A, Pasko, D, Peters, A, Poulter, N, Rayner, NW, Renström, F, Rolandsson, O, Sabater-Lleal, M, Sennblad, B, Sever, P, Shields, D, Silveira, A, Stanton, AV, Strauch, K, Tomaszewski, M, Tsafantakis, E, Waldenberger, M, Blakemore, AI, Dedoussis, G, Escher, SA, Kooner, JS, McCarthy, MI, Palmer, CN, Wellcome Trust Case Control Consortium, Hamsten, A, Caulfield, MJ, Frayling, TM, Tobin, MD, Jarvelin, MR, Zeggini, E, Gieger, C, Chambers, JC, Wareham, NJ, Munroe, PB, Franks, PW, Samani, NJ, Deloukas, P

Volltext

Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases von Ruffmann, C, Calboli, FC, Bravi, I, Gveric, D, Curry, LK, De Smith, A, Pavlou, S, Buxton, JL, Blakemore, AI, Takousis, P, Molloy, S, Piccini, P, Dexter, DT, Roncaroli, F, Gentleman, SM, Middleton, LT

Volltext

Limitations of the DiaRem Score in Predicting Remission of Diabetes Following Roux-En-Y Gastric Bypass (RYGB) in an ethnically Diverse Population from a Single Institution in the U... von Tharakan, G, Scott, R, Szepietowski, O, Miras, AD, Blakemore, AI, Purkayastha, S, Ahmed, A, Chahal, H, Tan, T

Volltext

A novel common variant in DCST2 is associated with length in early life and height in adulthood von Van der Valk, RJP, Kreiner-Moller, E, Kooijman, MN, Guxens, M, Saaf, A, Bradfield, JP, Hayes, MG, Cousminer, DL, Grallert, H, Custovic, A, Jacobsson, B, Jarvelin, M-R, Koppelman, GH, Pennell, CE, Niinikoski, H, Thiering, E, Frayling, TM, Sunyer, J, Timpson, NJ, Rivadeneira, F, Bonnelykke, K, Jaddoe, VWV, Curtin, JA, Myhre, R, Huikari, V, Joro, R, Kerkhof, M, Warrington, NM, Pitkanen, N, Horikoshi, M, Veijola, R, Teo, Y-Y, Barton, SJ, Kemp, JP, St Pourcain, B, Ring, SM, Smith, GD, Bergstrom, A, Kull, I, Hakonarson, H, Mentch, FD, Bisgaard, H, Chawes, B, Stokholm, J, Eriksen, P, Sevelsted, A, Melbye, M, Medina-Gomez, C, Hofman, A, De Jongste, JC, Taal, HR, Uitterlinden, AG, Armstrong, LL, Eriksson, J, Palotie, A, Bustamante, M, Estivill, X, Gonzalez, JR, Kiess, W, Mahajan, A, Flexeder, C, Tiesler, CMT, Murray, CS, Simpson, A, Sengpiel, V, Hartikainen, A-L, Lewin, A, Alves, ADSC, Blakemore, AI, Buxton, JL, Kaakinen, M, Rodriguez, A, Sebert, S, Vaarasmaki, M, Lakka, T, Lindi, V, Gehring, U, Postma, DS, Ang, W, Newnham, JP, Lyytikainen, L-P, Pahkala, K, Raitakari, OT, Panoutsopoulou, K, Zeggini, E, Boomsma, DI, Ilonen, J, Franke, L, Hirschhorn, JN, Pers, TH, Liang, L, Huang, J, Knip, M, Saw, S-M, Holloway, JW, Melen, E, Grant, SFA, Feenstra, B, Lowe, WL, Widen, E

Volltext

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity von Walters, RG, Coin, LJ, Ruokonen, A, De Smith, AJ, El-Sayed Moustafa, JS, Jacquemont, S, Elliott, P, Esko, T, Hartikainen, AL, Laitinen, J, Mannik, K, Martinet, D, Meyre, D, Nauck, M, Schurmann, C, Sladek, R, Thorleifsson, G, Thorsteinsdottir, U, Valsesia, A, Waeber, G, Zufferey, F, Balkau, B, Pattou, F, Metspalu, A, Volzke, H, Vollenweider, P, Stefansson, K, Jarvelin, MR, Beckmann, JS, Froguel, P, Blakemore, AI

Volltext

A mechanistic role for leptin in human dendritic cell migration: differences between ileum and colon in health and Crohn's disease von Al-Hassi, HO, Bernardo, D, Murugananthan, AU, Mann, ER, English, NR, Jones, A, Kamm, MA, Arebi, N, Hart, AL, Blakemore, AI, Stagg, AJ, Knight, SC

Volltext

Methylglyoxal modulates immune responses: relevance to diabetes von Price, CL, Hassi, HO, English, NR, Blakemore, AI, Stagg, AJ, Knight, SC

Volltext

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension von Cook, JP, Sim, X, Barnes, DR, Deloukas, P, Wellcome Trust Case Control Consortium, Elliott, P, Zeggini, E, Melander, O, Harakalova, M, Laakso, M, Padmanabhan, S, Hayward, C, Uusitupa, M, Mihailov, E, Newton-Cheh, C, Tobin, MD, T2D-GENES Consortium, Komulainen, P, CHD Exome+ Consortium, Caulfield, MJ, Morris, AP, Tomaszewski, M, Saleheen, D, Lakka, TA, Kraja, AT, Butterworth, AS, Rasheed, A, Samuel, M, Rauramaa, R, Zhao, W, Swift, AJ, Marten, J, Huyghe, JR, Fava, C, Stirrups, KE, Gjesing, AP, Rudan, I, Groves, CJ, Neville, MJ, Robertson, NR, Yiorkas, AM, Herzig, KH, Zhang, W, Rolandsson, O, Lannfelt, L, Malerba, G, Poveda, A, Franks, PW, De Craen, AJ, Trompet, S, Harris, SE, Liewald, DC, Marioni, R, Menni, C, Dedoussis, G, Hallmans, G, Hassinen, M, Felix, JF, CHARGE-Heart Failure Consortium, Uria-Nickelsen, M, Tragante, V, Malarstig, A, Hoek, M, Vogt, TF, Markus, HS, METASTROKE Consortium, Justice, AE, GIANT Consortium, EPIC-InterAct Consortium, Jousilahti, P, Männistö, S, Deary, IJ, Starr, JM, Brown, MJ, Connell, JM, Ford, I, Esko, T, Mägi, R, Van der Harst, P, Lind, L, Masca, N, Oksa, H, Kooner, JS, Blakemore, AI, Skaaby, T, Thuesen, B, Doney, AS, Morris, AD, Palmer, CN, Hveem, K, Groop, L, Käräjämäki, A, Ripatti, S, Alam, DS, Chowdhury, R, Poulter, N, Amouyel, P, Kuulasmaa, K, Müller-Nurasyid, M, Tinker, A

Volltext

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2 von Walters, RG, Jacquemont, S, Valsesia, A, De Smith, AJ, Martinet, D, Andersson, J, Falchi, M, Chen, F, Andrieux, J, Lobbens, S, Delobel, B, Stutzmann, F, El-Sayed Moustafa, JS, Chevre, JC, Lecoeur, C, Vatin, V, Bouquillon, S, Buxton, JL, Boute, O, Holder-Espinasse, M, Cuisset, JM, Lemaitre, MP, Ambresin, AE, Brioschi, A, Gaillard, M, Giusti, V, Fellmann, F, Ferrarini, A, Hadjikhani, N, Campion, D, Guilmatre, A, Goldenberg, A, Calmels, N, Mandel, JL, Le Caignec, C, David, A, Isidor, B, Cordier, MP, Dupuis-Girod, S, Labalme, A, Sanlaville, D, Beri-Dexheimer, M, Jonveaux, P, Leheup, B, Ounap, K, Bochukova, EG, Henning, E, Keogh, J, Ellis, RJ, Macdermot, KD, Van Haelst, MM, Vincent-Delorme, C, Plessis, G, Touraine, R, Philippe, A, Malan, V, Mathieu-Dramard, M, Chiesa, J, Blaumeiser, B, Kooy, RF, Caiazzo, R, Pigeyre, M, Balkau, B, Sladek, R, Bergmann, S, Mooser, V, Waterworth, D, Reymond, A, Vollenweider, P, Waeber, G, Kurg, A, Palta, P, Esko, T, Metspalu, A, Nelis, M, Elliott, P, Hartikainen, AL, McCarthy, MI, Peltonen, L, Carlsson, L, Jacobson, P, Sjostrom, L, Huang, N, Hurles, ME, O'Rahilly, S, Farooqi, IS, Mannik, K, Jarvelin, MR, Pattou, F, Meyre, D, Walley, AJ, Coin, LJ, Blakemore, AI, Froguel, P, Beckmann, JS

Volltext

Association between interleukin-1 receptor antagonist (IL-1ra) gene polymorphism and early and late-onset psoriasis von Tarlow, J.K., Cork, M.J., Clay, F.E., Schmitt-Egenolf, M., Crane, A.M., Stierle, C., Eoehncke, W.-H., Eiermann, T.H., Blakemore, A.I.F., Bleehen, S.S., Sterry, W., Duff, G.W.

Volltext

A genome-wide association meta-analysis identifies new childhood obesity loci von Bradfield JP, -, Taal HR, -, Timpson NJ, -, Scherag A, -, Lecoeur C, -, Warrington NM, -, Hypponen E, -, Holst C, -, Valcarcel B, -, Thiering E, -, Salem RM, -, Schumacher FR, -, Cousminer DL, -, Sleiman PM, -, Zhao J, -, Berkowitz RI, -, Vimaleswaran KS, -, Jarick I, -, Pennell CE, -, Evans DM, -, St Pourcain B, -, Berry DJ, -, Mook-Kanamori DO, -, Hofman A, -, Rivadeneira F, -, Uitterlinden AG, -, Van Duijn CM, -, Van der Valk RJ, -, De Jongste JC, -, Postma DS, -, Boomsma DI, -, Gauderman WJ, -, Hassanein MT, -, Lindgren CM, -, Mägi R, -, Boreham CA, -, Neville CE, -, Moreno LA, -, Elliott P, -, Pouta A, -, Hartikainen AL, -, Li M, -, Raitakari O, -, Lehtimäki T, -, Eriksson JG, -, Palotie A, -, Dallongeville J, -, Das S, -, Deloukas P, -, McMahon G, -, Ring SM, -, Kemp JP, -, Buxton JL, -, Blakemore AI, -, Bustamante M, -, Guxens M, -, Hirschhorn JN, -, Gillman MW, -, Kreiner-Møller E, -, Bisgaard H, -, Gilliland FD, -, Heinrich J, -, Wheeler E, -, Barroso I, -, O'Rahilly S, -, Meirhaeghe A, -, Sørensen TI, -, Power C, -, Palmer LJ, -, Hinney A, -, Widen E, -, Farooqi IS, -, McCarthy MI, -, Froguel P, -, Meyre D, -, Hebebrand J, -, Jarvelin MR, -, Jaddoe VW, -, Smith GD, -, Hakonarson H, -, Grant, SF

Volltext

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis von Paternoster, L, Standl, M, Chen, CM, Ramasamy, A, Bonnelykke, K, Duijts, L, Ferreira, MA, Alves, AC, Thyssen, JP, Albrecht, E, Baurecht, H, Feenstra, B, Sleiman, PM, Hysi, P, Warrington, NM, Curjuric, I, Myhre, R, Curtin, JA, Groen-Blokhuis, MM, Kerkhof, M, Saaf, A, Franke, A, Ellinghaus, D, Folster-Holst, R, Dermitzakis, E, Montgomery, SB, Prokisch, H, Heim, K, Hartikainen, AL, Pouta, A, Pekkanen, J, Blakemore, AI, Buxton, JL, Kaakinen, M, Duffy, DL, Madden, PA, Heath, AC, Montgomery, GW, Thompson, PJ, Matheson, MC, Le Souef, P, St Pourcain, B, Smith, GD, Henderson, J, Kemp, JP, Timpson, NJ, Deloukas, P, Ring, SM, Wichmann, HE, Muller-Nurasyid, M, Novak, N, Klopp, N, Rodriguez, E, McArdle, W, Linneberg, A, Menne, T, Nohr, EA, Hofman, A, Uitterlinden, AG, Van Duijn, CM, Rivadeneira, F, De Jongste, JC, Van der Valk, RJ, Wjst, M, Jogi, R, Geller, F, Boyd, HA, Murray, JC, Kim, C, Mentch, F, March, M, Mangino, M, Spector, TD, Bataille, V, Pennell, CE, Holt, PG, Sly, P, Tiesler, CM, Thiering, E, Illig, T, Imboden, M, Nystad, W, Simpson, A, Hottenga, JJ, Postma, D, Koppelman, GH, Smit, HA, Soderhall, C, Chawes, B, Kreiner-Moller, E, Bisgaard, H, Melen, E, Boomsma, DI, Custovic, A, Jacobsson, B, Probst-Hensch, NM, Palmer, LJ, Glass, D, Hakonarson, H, Melbye, M

Volltext

Quantified-self for obesity: physical activity behaviour sensing to improve health outcomes von Taylor, D, Murphy, J, Ahmad, M, Purkayastha, S, Scholtz, S, Ramezani, R, Vlaev, I, Blakemore, AI, Darzi, A

Volltext

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index von Speliotes, EK, Willer, CJ, Berndt, SI, Monda, KL, Thorleifsson, G, Jackson, AU, Lango Allen, H, Lindgren, CM, Luan, J, Magi, R, Randall, JC, Vedantam, S, Winkler, TW, Qi, L, Workalemahu, T, Heid, IM, Steinthorsdottir, V, Stringham, HM, Weedon, MN, Wheeler, E, Wood, AR, Ferreira, T, Weyant, RJ, Segre, AV, Estrada, K, Liang, L, Nemesh, J, Park, JH, Gustafsson, S, Kilpelainen, TO, Yang, J, Bouatia-Naji, N, Esko, T, Feitosa, MF, Kutalik, Z, Mangino, M, Raychaudhuri, S, Scherag, A, Smith, AV, Welch, R, Zhao, JH, Aben, KK, Absher, DM, Amin, N, Dixon, AL, Fisher, E, Glazer, NL, Goddard, ME, Heard-Costa, NL, Hoesel, V, Hottenga, JJ, Johansson, A, Johnson, T, Ketkar, S, Lamina, C, Li, S, Moffatt, MF, Myers, RH, Narisu, N, Perry, JR, Peters, MJ, Preuss, M, Ripatti, S, Rivadeneira, F, Sandholt, C, Scott, LJ, Timpson, NJ, Tyrer, JP, Van Wingerden, S, Watanabe, RM, White, CC, Wiklund, F, Barlassina, C, Chasman, DI, Cooper, MN, Jansson, JO, Lawrence, RW, Pellikka, N, Prokopenko, I, Shi, J, Thiering, E, Alavere, H, Alibrandi, MT, Almgren, P, Arnold, AM, Aspelund, T, Atwood, LD, Balkau, B, Balmforth, AJ, Bennett, AJ, Ben-Shlomo, Y, Bergman, RN, Bergmann, S, Biebermann, H, Blakemore, AI, Boes, T, Bonnycastle, LL, Bornstein, SR, Brown, MJ, Buchanan, TA

Volltext