Innovations, challenges, and minimal information for standardization of humanized mice von Stripecke, Renata, Münz, Christian, Schuringa, Jan Jacob, Bissig, Karl‐Dimiter, Soper, Brian, Meeham, Terrence, Yao, Li‐Chin, Di Santo, James P, Brehm, Michael, Rodriguez, Estefania, Wege, Anja Kathrin, Bonnet, Dominique, Guionaud, Silvia, Howard, Kristina E, Kitchen, Scott, Klein, Florian, Saeb‐Parsy, Kourosh, Sam, Johannes, Sharma, Amar Deep, Trumpp, Andreas, Trusolino, Livio, Bult, Carol, Shultz, Leonard

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The camKK2/camKIV relay is an essential regulator of hepatic cancer von Lin, Fumin, Marcelo, Kathrina L., Rajapakshe, Kimal, Coarfa, Cristian, Dean, Adam, Wilganowski, Nathaniel, Robinson, Holly, Sevick, Eva, Bissig, Karl‐Dimiter, Goldie, Lauren C., Means, Anthony R., York, Brian

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Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia von Pankowicz, Francis P., Barzi, Mercedes, Legras, Xavier, Hubert, Leroy, Mi, Tian, Tomolonis, Julie A., Ravishankar, Milan, Sun, Qin, Yang, Diane, Borowiak, Malgorzata, Sumazin, Pavel, Elsea, Sarah H., Bissig-Choisat, Beatrice, Bissig, Karl-Dimiter

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A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity von Ruiz, Sergio, Panopoulos, Athanasia D., Herrerías, Aída, Bissig, Karl-Dimiter, Lutz, Margaret, Berggren, W. Travis, Verma, Inder M., Izpisua Belmonte, Juan Carlos

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Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment von Bissig, Karl-Dimiter, Wieland, Stefan F, Tran, Phu, Isogawa, Masanori, Le, Tam T, Chisari, Francis V, Verma, Inder M

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P450-Humanized and Human Liver Chimeric Mouse Models for Studying Xenobiotic Metabolism and Toxicity von Bissig, Karl-Dimiter, Han, Weiguo, Barzi, Mercedes, Kovalchuk, Nataliia, Ding, Liang, Fan, Xiaoyu, Pankowicz, Francis P, Zhang, Qing-Yu, Ding, Xinxin

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A humanized mouse model for adeno-associated viral gene therapy von Barzi, Mercedes, Chen, Tong, Gonzalez, Trevor J., Pankowicz, Francis P., Oh, Seh Hoon, Streff, Helen L., Rosales, Alan, Ma, Yunhan, Collias, Sabrina, Woodfield, Sarah E., Diehl, Anna Mae, Vasudevan, Sanjeev A., Galvan, Thao N., Goss, John, Gersbach, Charles A., Bissig-Choisat, Beatrice, Asokan, Aravind, Bissig, Karl-Dimiter

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CRISPR/Cas9: at the cutting edge of hepatology von Pankowicz, Francis P, Jarrett, Kelsey E, Lagor, William R, Bissig, Karl-Dimiter

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A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism von Barzi, Mercedes, Pankowicz, Francis P., Zorman, Barry, Liu, Xing, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Bissig-Choisat, Beatrice, Sumazin, Pavel, Li, Feng, Bissig, Karl-Dimiter

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Generation of model tissues with dendritic vascular networks via sacrificial laser-sintered carbohydrate templates von Kinstlinger, Ian S., Saxton, Sarah H., Calderon, Gisele A., Ruiz, Karen Vasquez, Yalacki, David R., Deme, Palvasha R., Rosenkrantz, Jessica E., Louis-Rosenberg, Jesse D., Johansson, Fredrik, Janson, Kevin D., Sazer, Daniel W., Panchavati, Saarang S., Bissig, Karl-Dimiter, Stevens, Kelly R., Miller, Jordan S.

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Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model von Bissig, Karl-Dimiter, Le, Tam T, Woods, Niels-Bjarne, Verma, Inder M

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Differentiation of spontaneously contracting cardiomyocytes from non-virally reprogrammed human amniotic fluid stem cells von Velasquez-Mao, Aaron J, Tsao, Christopher J M, Monroe, Madeline N, Legras, Xavier, Bissig-Choisat, Beatrice, Bissig, Karl-Dimiter, Ruano, Rodrigo, Jacot, Jeffrey G

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Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model von Bissig-Choisat, Beatrice, Wang, Lili, Legras, Xavier, Saha, Pradip K., Chen, Leon, Bell, Peter, Pankowicz, Francis P., Hill, Matthew C., Barzi, Mercedes, Leyton, Claudia Kettlun, Leung, Hon-Chiu Eastwood, Kruse, Robert L., Himes, Ryan W., Goss, John A., Wilson, James M., Chan, Lawrence, Lagor, William R., Bissig, Karl-Dimiter

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Using CRISPR/Cas9 to model human liver disease von Alves-Bezerra, Michele, Furey, Nika, Johnson, Collin G., Bissig, Karl-Dimiter

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A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma von Woodfield, Sarah E., Shi, Yan, Patel, Roma H., Jin, Jingling, Major, Angela, Sarabia, Stephen F., Starosolski, Zbigniew, Zorman, Barry, Gupta, Siddharth S., Chen, Zhenghu, Ibarra, Aryana M., Bissig, Karl-Dimiter, Ghaghada, Ketan B., Sumazin, Pavel, López-Terrada, Dolores, Vasudevan, Sanjeev A.

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Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex von Minor, Marissa M., Hollinger, F. Blaine, McNees, Adrienne L., Jung, Sung Yun, Jain, Antrix, Hyser, Joseph M., Bissig, Karl-Dimiter, Slagle, Betty L.

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A human liver chimeric mouse model for non-alcoholic fatty liver disease von Bissig-Choisat, Beatrice, Alves-Bezerra, Michele, Zorman, Barry, Ochsner, Scott A., Barzi, Mercedes, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Dean, Adam M., York, Robert B., Galvan, N. Thao N., Goss, John, Lagor, William R., Moore, David D., Cohen, David E., McKenna, Neil J., Sumazin, Pavel, Bissig, Karl-Dimiter

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Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism von Barzi, Mercedes, Pankowicz, Francis P., Zorman, Barry, Liu, Xing, Legras, Xavier, Yang, Diane, Borowiak, Malgorzata, Bissig-Choisat, Beatrice, Sumazin, Pavel, Li, Feng, Bissig, Karl-Dimiter

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Somatic Liver Knockout (SLiK): A Quick and Efficient Way to Generate Liver‐Specific Knockout Mice Using Multiplex CRISPR/Cas9 Gene Editing von Johnson, Collin G., Chen, Tong, Furey, Nika, Hemmingsen, Madeline G., Bissig, Karl‐Dimiter

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PARP1 activation increases expression of modified tumor suppressors and pathways underlying development of aggressive hepatoblastoma von Valanejad, Leila, Cast, Ashley, Wright, Mary, Bissig, Karl-Dimiter, Karns, Rebekah, Weirauch, Matthew T., Timchenko, Nikolai

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