Antitumor activity of the PI3K [delta]-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer von Fiascarelli, Alessio, Merlino, Giuseppe, Capano, Stefania, Talucci, Simone, Bisignano, Diego, Bressan, Alessandro, Bellarosa, Daniela

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Tagraxofusp Shows Promising Anti-Tumoral Efficacy in Preclinical in Vitro Models of Myelofibrosis, Both As a Single Agent and in Combination with Janus Kinase Inhibitors von Iannitto, Maria Luisa, Bisignano, Diego, Fiascarelli, Alessio, Talucci, Simone, Zicari, Sonia, Belli, Francesco, Bressan, Alessandro, Brooks, Christopher, Bellarosa, Daniela, Binaschi, Monica

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The Dual PIM/FLT3 Inhibitor MEN1703 Combines Synergistically With Gilteritinib in FLT3‐ITD‐Mutant Acute Myeloid Leukaemia von Zicari, Sonia, Merlino, Giuseppe, Paoli, Alessandro, Fiascarelli, Alessio, Tunici, Patrizia, Bisignano, Diego, Belli, Francesco, Irrissuto, Clelia, Talucci, Simone, Cirigliano, Elena, Iannitto, Maria Luisa, Bigioni, Mario, Bressan, Alessandro, Brzózka, Krzysztof, Ghiaur, Gabriel, Bellarosa, Daniela, Binaschi, Monica

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Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer von Fiascarelli, Alessio, Merlino, Giuseppe, Capano, Stefania, Talucci, Simone, Bisignano, Diego, Bressan, Alessandro, Bellarosa, Daniela, Carrisi, Corrado, Paoli, Alessandro, Bigioni, Mario, Tunici, Patrizia, Irrissuto, Clelia, Salerno, Massimiliano, Arribas, Joaquin, de Stanchina, Elisa, Scaltriti, Maurizio, Binaschi, Monica

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Abstract 1170: MEN1112/OBT357, a first-in-class humanized de-fucosylated monoclonal antibody targeting CD157 positive cells in acute myeloid leukemia and myelodysplastic syndrome von Carrisi, Corrado, Bellarosa, Daniela, Bisignano, Diego, Venditti, Adriano, Buccisano, Francesco, Sconocchia, Giuseppe, Coppola, Andrea, Aureli, Anna, Fiascarelli, Alessio, Bressan, Alessandro, Baldini, Simone, Pellacani, Andrea, Binaschi, Monica

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PIM Inhibition By SEL24/MEN1703 Combines Synergistically with Gilteritinib in FLT3-ITD Preclinical Models of Acute Myeloid Leukemia von Bellarosa, Daniela, Zicari, Sonia, Merlino, Giuseppe, Fiascarelli, Alessio, Bisignano, Diego, Belli, Francesco, Irrissuto, Clelia, Talucci, Simone, Iannitto, Maria Luisa, Bigioni, Mario, Bressan, Alessandro, Brzózka, Krzysztof, Ghiaur, Gabriel, Binaschi, Monica

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Abstract PS18-13: Men1611 is a pi3k α/β selective and δ sparing inhibitor with long-lasting antitumor activity in different genetic backgrounds of pik3ca mutant breast cancer model... von Fiascarelli, Alessio, Carrisi, Corrado, Merlino, Giuseppe, Capano, Stefania, Bisignano, Diego, Talucci, Simone, Bressan, Alessandro, Bellarosa, Daniele, Bigioni, Mario, Scaltriti, Maurizio, Arribas, Joaquin, Pellacani, Andrea, Salerno, Massimiliano, Binaschi, Monica

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