RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease von Bishof, Isaac, Dammer, Eric B., Duong, Duc M., Kundinger, Sean R., Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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An Intrinsically Disordered Low Complexity Domain is Required for U1‐70K Self‐association von Bishof, Isaac, Diner, Ian, Seyfried, Nicholas

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Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins von Kundinger, Sean R, Bishof, Isaac, Dammer, Eric B, Duong, Duc M, Seyfried, Nicholas T

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Dynamic ADP-Ribosylome, Phosphoproteome, and Interactome in LPS-Activated Macrophages von Daniels, Casey M, Kaplan, Pauline R, Bishof, Isaac, Bradfield, Clinton, Tucholski, Trisha, Nuccio, Arthur G, Manes, Nathan P, Katz, Samuel, Fraser, Iain D. C, Nita-Lazar, Aleksandra

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Aggregation Properties of the Small Nuclear Ribonucleoprotein U1-70K in Alzheimer Disease von Diner, Ian, Hales, Chadwick M., Bishof, Isaac, Rabenold, Lake, Duong, Duc M., Yi, Hong, Laur, Oskar, Gearing, Marla, Troncoso, Juan, Thambisetty, Madhav, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE von Bishof, Isaac J., Dammer, Eric B., Duong, Duc, Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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O2‐02‐05: RNA‐BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF‐ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE von Bishof, Isaac J., Dammer, Eric B., Duong, Duc, Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.

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Abstract 1637: MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations von Gerrick, Kimberline Y., Laraio, Jenny, Annen, Kelsey, Tran, Hoang, Fischer, Marcus M., Freyman, Yevgeniy, Sharma, Geeta, Bishof, Isaac, Federowicz, Stephen, Pankajakshan, Divya, Neilan, Claire L., Mangatt, Biju, Mazurek, Anthony, Lackner, Mark R., White, Michael, Mounir, Zineb

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Abstract 1644: Dual inhibition of MAT2A and PRMT5 delivers synergistic anti-tumor responses in preclinical models of MTAP -deleted cancer von Fischer, Marcus M., Gerrick, Kimberline, Belmontes, Brian, Slemmons, Katherine, Freyman, Yevgeniy, Jain, Jay, Federowicz, Steve, Bishof, Isaac, Rao, Arjun A., Fleury, Melissa, Mounir, Zineb, Lackner, Mark R., Hughes, Paul E., White, Mike, Neilan, Claire L.

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