IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer von van Baarle, Lies, De Simone, Veronica, Schneider, Linda, Santhosh, Sneha, Abdurahiman, Saeed, Biscu, Francesca, Schneider, Reiner, Zanoletti, Lisa, Siqueira de Mello, Renata, Verbandt, Sara, Hu, Zedong, Stakenborg, Michelle, Ke, Bo-Jun, Stakenborg, Nathalie, Salvador Laureano, Raquel, García-Reyes, Balbina, Henn, Jonas, Toma, Marieta, Vanmechelen, Maxime, Boeckxstaens, Guy, De Smet, Frederik, Garg, Abhishek D., Ibiza, Sales, Tejpar, Sabine, Wehner, Sven, Matteoli, Gianluca

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Innate immunity champions: The diverse functions of macrophages von Biscu, Francesca, Zouzaf, anissa, Cicia, donatella, Pridans, Clare, Matteoli, gianluca

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Innate immunity champions: The diverse functions of macrophages von Biscu, Francesca, Zouzaf, Anissa, Cicia, Donatella, Pridans, Clare, Matteoli, Gianluca

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415 NEUTROPHIL EXTRACELLULAR TRAPS ENHANCE PROFIBROTIC ACTIVITY OF INTESTINAL FIBROBLASTS IN CROHN'S DISEASE THROUGH TLR2/NF-KB PATHWAY von Dragoni, Gabriele, Ke, Bo-Jun, Picariello, Lucia, Ceni, Elisabetta, Mello, Tommaso, Verstockt, Bram, Abdurahiman, Saeed, Biscu, Francesca, Innocenti, Tommaso, De Hertogh, Gert, Martinod, Kimberly, Galli, Andrea, Matteoli, Gianluca, Vermeire, Séverine

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Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action von Covelli, Verdiana, Buonocore, Michela, Grimaldi, Manuela, Scrima, Mario, Santoro, Angelo, Marino, Carmen, De Simone, Veronica, van Baarle, Lies, Biscu, Francesca, Scala, Maria Carmina, Sala, Marina, Matteoli, Gianluca, D'Ursi, Anna Maria, Rodriquez, Manuela

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Peptides as modulators of FPPS enzyme: A multifaceted evaluation from the design to the mechanism of action von Covelli, Verdiana, Buonocore, Michela, Grimaldi, Manuela, Scrima, Mario, Santoro, Angelo, Marino, Carmen, De Simone, Veronica, van Baarle, Lies, Biscu, Francesca, Scala, Maria Carmina, Sala, Marina, Matteoli, Gianluca, D'Ursi, Anna Maria, Rodriquez, Manuela

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Intercellular interaction between [FAP.sup.+] fibroblasts and [CD150.sup.+] inflammatory monocytes mediates fibrostenosis in Crohn's disease von Ke, Bo-Jun, Abdurahiman, Saeed, Biscu, Francesca, Zanella, Gaia, Dragoni, Gabriele, Santhosh, Sneha, De Simone, Veronica, Zouzaf, Anissa, van Baarle, Lies, Stakenborg, Michelle, Bosakova, Veronika, Van Rymenant, Yenti, Verhulst, Emile, Verstockt, Sare, Klein, Elliott, Bislenghi, Gabriele, Wolthuis, Albert, Fric, Jan, Breynaert, Christine, D'Hoore, Andre, Van der Veken, Pieter, De Meester, Ingrid, Lovisa, Sara, Hawinkels, Lukas J.A.C, Verstockt, Bram, De Hertogh, Gert, Vermeire, Severine, Matteoli, Gianluca

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Intercellular interaction between FAP+ fibroblasts and CD150+inflammatory monocytes mediates fibrostenosis in Crohn's disease von Ke, Bo-Jun, Abdurahiman, Saeed, Biscu, Francesca, Zanella, Gaia, Dragoni, Gabriele, Santhosh, Sneha, De Simone, Veronica, Zouzaf, Anissa, van Baarle, Lies, Stakenborg, Michelle, Bosakova, Veronika, Van Rymenant, Yentl, Verhulst, Emile, Verstockt, Sare, Klein, Elliott, Bislenghi, Gabriele, Wolthuis, Albert, Fric, Jan, Breynaert, Christine, D'Hoore, Andre, van der Veken, Pieter, De Meester, Ingrid, Lovisa, Sara, Hawinkels, Lukas J.A.C, Verstockt, Bram, De Hertogh, Gert, Vermeire, Severine, Matteoli, Gianluca

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IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer von van Baarle, Lies, De Simone, Veronica, Schneider, Linda, Santhosh, Sneha, Abdurahiman, Saeed, Biscu, Francesca, Schneider, Reiner, Zanoletti, Lisa, de Mello, Renata Siqueira, Verbandt, Sara, Hu, Zedong, Stakenborg, Michelle, Ke, Bo-Jun, Stakenborg, Nathalie, Laureano, Raquel Salvador, Garcia-Reyes, Balbina, Henn, Jonas, Toma, Marieta, Vanmechelen, Maxime, Boeckxstaens, Guy, De Smet, Frederik, Garg, Abhishek D, Ibiza, Sales, Tejpar, Sabine, Wehner, Sven, Matteoli, Gianluca

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Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn’s disease von Ke, Bo-Jun, Abdurahiman, Saeed, Biscu, Francesca, Zanella, Gaia, Dragoni, Gabriele, Santhosh, Sneha, De Simone, Veronica, Zouzaf, Anissa, van Baarle, Lies, Stakenborg, Michelle, Bosáková, Veronika, Van Rymenant, Yentl, Verhulst, Emile, Verstockt, Sare, Klein, Elliott, Bislenghi, Gabriele, Wolthuis, Albert, Frič, Jan, Breynaert, Christine, D’Hoore, Andre, Van der Veken, Pieter, De Meester, Ingrid, Lovisa, Sara, Hawinkels, Lukas J.A.C., Verstockt, Bram, De Hertogh, Gert, Vermeire, Séverine, Matteoli, Gianluca

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The Impact of Peptidyl Arginine Deiminase 4-Dependent Neutrophil Extracellular Trap Formation on the Early Development of Intestinal Fibrosis in Crohn's Disease von Dragoni, Gabriele, Ke, Bo-Jun, Picariello, Lucia, Abdurahiman, Saeed, Ceni, Elisabetta, Biscu, Francesca, Mello, Tommaso, Polvani, Simone, Innocenti, Tommaso, Spalart, Valérie, Milani, Stefano, D'Hoore, André, Bislenghi, Gabriele, Scaringi, Stefano, Verstockt, Bram, De Hertogh, Gert, Martinod, Kimberly, Galli, Andrea, Matteoli, Gianluca, Vermeire, Séverine

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The Impact of Peptidyl Arginine Deiminase 4-Dependent Neutrophil Extracellular Trap Formation on the Early Development of Intestinal Fibrosis in Crohn's Disease von Dragoni, Gabriele, Ke, Bo-Jun, Picariello, Lucia, Abdurahiman, Saeed, Ceni, Elisabetta, Biscu, Francesca, Mello, Tommaso, Polvani, Simone, Innocenti, Tommaso, Spalart, Valerie, Milani, Stefano, D'Hoore, Andre, Bislenghi, Gabriele, Scaringi, Stefano, Verstockt, Bram, De Hertogh, Gert, Martinod, Kimberly, Galli, Andrea, Matteoli, Gianluca, Vermeire, Severine

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Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibro-stenosis in Crohn's disease von Ke, Bo-Jun, Abdurahiman, Saeed, Biscu, Francesca, Zanella, Gaia, Dragoni, Gabriele, Santhosh, Sneha, De Simone, Veronica, Zouzaf, Anissa, van Baarle, Lies, Stakenborg, Michelle, Bosáková, Veronika, Van Rymenant, Yentl, Verhulst, Emile, Verstockt, Sare, Klein, Elliott, Bislenghi, Gabriele, Wolthuis, Albert M, Frič, Jan, Breynaert, Christine, D'Hoore, Andre, Van der Veken, Pieter, De Meester, Ingrid, Lovisa, Sara, Hawinkels, Lukas Jac, Verstockt, Bram, De Hertogh, Gert, Vermeire, Séverine, Matteoli, Gianluca

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Pharmacological or genetic targeting of TRPM8 regulates M1 macrophages proinflammatory capacity and their metabolic switch von Cicia, Donatella, Biscu, Francesca, Iaccarino, Nunzia, Lucariello, Giuseppe, Nani, Maria Francesca, Iannotti, Fabio Arturo, Randazzo, Antonio, Capasso, Raffaele, Matteoli, Gianluca, Izzo, Angelo Antonio, Pagano, Ester

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Dietary targeting of TRPM8 rewires macrophage immunometabolism reducing colitis severity von Cicia, Donatella, Biscu, Francesca, Iannotti, Fabio A, Miraglia, Maria, Ferrante, Claudio, Iaccarino, Nunzia, Cadenas de Miguel, Silvia, Chiavaroli, Annalisa, Schiano Moriello, Aniello, De Cicco, Paola, Nanì, Maria Francesca, Zanoletti, Lisa, Ke, Bo-Jun, van Baarle, Lies, Talavera Pérez, Karel, Randazzo, Antonio, Elia, Ilaria, Capasso, Raffaele, Matteoli, Gianluca, Pagano, Ester, Izzo, Angelo Antonio

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