Histone Modification Landscapes as a Roadmap for Malaria Parasite Development von Connacher, J, von Grüning, H, Birkholtz, L

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In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species von Moyo, P., Botha, M.E., Nondaba, S., Niemand, J., Maharaj, V.J., Eloff, J.N., Louw, A.I., Birkholtz, L.

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Polyamine uptake by the intraerythrocytic malaria parasite, Plasmodium falciparum von Niemand, J., Louw, A.I., Birkholtz, L., Kirk, K.

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Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum von Clark, K, Niemand, J, Reeksting, S, Smit, S, van Brummelen, A. C, Williams, M, Louw, A. I, Birkholtz, L

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Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential von Niemand, J, Birkholtz, L, Louw, AI, Kirk, K

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Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential von Niemand, J, Birkholtz, L, Louw, A I, Kirk, K

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Exploring functional genomics for drug target and therapeutics discovery in Plasmodia von Birkholtz, L., van Brummelen, A.C., Clark, K., Niemand, J., Maréchal, E., Llinás, M., Louw, A.I.

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Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interacti... von Birkholtz, Lyn-Marie, Wrenger, Carsten, Joubert, Fourie, Wells, Gordon A, Walter, Rolf D, Louw, Abraham I

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Comparative properties of a three-dimensional model of Plasmodium falciparum ornithine decarboxylase von Birkholtz, L., Joubert, F., Neitz, A.W.H., Louw, A.I.

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Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase von Paquet, T, Le Manach, C, Cabrera, DG, Younis, Y, Henrich, PP, Abraham, TS, Lee, MCS, Basak, R, Ghidelli-Disse, S, Lafuente-Monasterio, MJ, Bantscheff, M, Ruecker, A, Blagborough, AM, Zakutansky, SE, Zeeman, A-M, White, KL, Shackleford, DM, Mannila, J, Morizzi, J, Scheurer, C, Angulo-Barturen, I, Martinez, MS, Ferrer, S, Sanz, LM, Gamo, FJ, Reader, J, Botha, M, Dechering, KJ, Sauerwein, RW, Tungtaeng, A, Vanachayangkul, P, Lim, CS, Burrows, J, Witty, MJ, Marsh, KC, Bodenreider, C, Rochford, R, Solapure, SM, Jimenez-Diaz, MB, Wittlin, S, Charman, SA, Donini, C, Campo, B, Birkholtz, L-M, Hanson, KK, Drewes, G, Kocken, CHM, Delves, MJ, Leroy, D, Fidock, DA, Waterson, D, Street, LJ, Chibale, K

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Drug-resistant and mixed-species malaria infections in Mpumalanga, South Africa von Birkholtz, L, Visser, L, Brink, A, Louw, AI

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Review: Exploring functional genomics for drug target and therapeutics discovery in Plasmodia von Birkholtz, L, van Brummelen, A C, Clark, K, Niemand, J, Marechal, E, Llinas, M, Louw, A I

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The prevalence of mixed-species and antifolate-resistant malaria infections in Mpumalanga von Birkholtz, L, Visser, L, Louw, A I, van der Linde, R, Brink, A J

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Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling von Wells, Gordon A., Birkholtz, Lyn-Marie, Joubert, Fourie, Walter, Rolf D., Louw, Abraham I.

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Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and In Vivo Efficacy in the Plasmodium falciparum NSG Mouse Model von Horatscheck, A, Andrijevic, A, Nchinda, AT, Le Manach, C, Paquet, T, Khonde, LP, Dam, J, Pawar, K, Taylor, D, Lawrence, N, Brunschwig, C, Gibhard, L, Njoroge, M, Reader, J, van der Watt, M, Wicht, K, de Sousa, ACC, Okombo, J, Maepa, K, Egan, TJ, Birkholtz, L-M, Basarab, GS, Wittlin, S, Fish, PV, Street, LJ, Duffy, J, Chibale, K

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Use of regression analysis to forecast cash flows von Klerck, W. G, Birkholtz, L. E

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UCT943, a next generation Plasmodium falciparum PI4K inhibitor preclinical candidate for the treatment of malaria von Brunschwig, C, Lawrence, N, Taylor, D, Abay, E, Njoroge, M, Basarab, GS, Le Manach, C, Paquet, T, Gonzàlez Cabrera, D, Nchinda, AT, de Kock, C, Wiesner, L, Denti, P, Waterson, D, Blasco, B, Leroy, D, Witty, MJ, Donini, C, Duffy, J, Wittlin, S, White, KL, Charman, SA, Jiménez-Díaz, MB, Angulo-Barturen, I, Herreros, E, Gamo, FJ, Rochford, R, Mancama, D, Coetzer, TL, van der Watt, ME, Reader, J, Birkholtz, L-M, Marsh, KC, Solapure, SM, Vanaerschot, M, Fidock, DA, Fish, PV, Siegl, P, Smith, DA, Wirjanata, G, Noviyanti, R, Price, RN, Marfurt, J, Silue, KD, Street, LJ, Chibale, K

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New Transmission‐Selective Antimalarial Agents through Hit‐to‐Lead Optimization of 2‐([1,1′‐Biphenyl]‐4‐carboxamido)benzoic Acid Derivatives von Reader, Janette, Opperman, Daniel F. L., Watt, Mariëtte E., Theron, Anjo, Leshabane, Meta, Rocha, Shanté, Turner, Jonathan, Garrabrant, Kathleen, Piña, Ivett, Mills, Catherine, Woster, Patrick M., Birkholtz, Lyn‐Marié

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Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space? von Birkholtz, L. -M, Bastien, O, Wells, G, Grando, D, Joubert, F, Kasam, V, Zimmermann, M, Ortet, P, Jacq, N, Roy, S, Hoffmann-Apitius, M, Breton, V, Louw, A. I, Maréchal, E

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Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box von Reader, Janette, van der Watt, Mariëtte E., Taylor, Dale, Le Manach, Claire, Mittal, Nimisha, Ottilie, Sabine, Theron, Anjo, Moyo, Phanankosi, Erlank, Erica, Nardini, Luisa, Venter, Nelius, Lauterbach, Sonja, Bezuidenhout, Belinda, Horatscheck, Andre, van Heerden, Ashleigh, Spillman, Natalie J., Cowell, Anne N., Connacher, Jessica, Opperman, Daniel, Orchard, Lindsey M., Llinás, Manuel, Istvan, Eva S., Goldberg, Daniel E., Boyle, Grant A., Calvo, David, Mancama, Dalu, Coetzer, Theresa L., Winzeler, Elizabeth A., Duffy, James, Koekemoer, Lizette L., Basarab, Gregory, Chibale, Kelly, Birkholtz, Lyn-Marié

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