Beyond the 'big four': Venom profiling of the medically important yet neglected Indian snakes reveals disturbing antivenom deficiencies von Senji Laxme, R R, Khochare, Suyog, de Souza, Hugo Francisco, Ahuja, Bharat, Suranse, Vivek, Martin, Gerard, Whitaker, Romulus, Sunagar, Kartik

Volltext

Scorpion envenomation-associated myocarditis: A systematic review von Fereidooni, Reza, Shirzadi, Saeedreza, Ayatizadeh, Seyyed Hamidreza, Bahloul, Mabrouk, Tavangar, Amirali, Zomorodian, Seyed Alireza, Roshanshad, Amirhossein, Ardekani, Ali

Volltext

The nociceptive response induced by different classes of Tityus serrulatus neurotoxins: The important role of Ts5 in venom-induced nociception von Cerni, Felipe, Oliveira, Isadora, Cordeiro, Francielle, Bordon, Karla, Ferreira, Isabela, Monteiro, Wuelton, Arantes, Eliane, Cunha, Thiago, Pucca, Manuela

Volltext

Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically... von Alomran, Nessrin, Alsolaiss, Jaffer, Albulescu, Laura-Oana, Crittenden, Edouard, Harrison, Robert A., Ainsworth, Stuart, Casewell, Nicholas R.

Volltext

Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephr... von Chaisakul, Janeyuth, Alsolaiss, Jaffer, Charoenpitakchai, Mongkon, Wiwatwarayos, Kulachet, Sookprasert, Nattapon, Harrison, Robert A, Chaiyabutr, Narongsak, Chanhome, Lawan, Tan, Choo Hock, Casewell, Nicholas R

Volltext

Rutin (quercetin-3-rutinoside) modulates the hemostatic disturbances and redox imbalance induced by Bothrops jararaca snake venom in mice von Sachetto, Ana Teresa Azevedo, Rosa, Jaqueline Gomes, Santoro, Marcelo Larami

Volltext

Scorpion envenomation in Brazil: Current scenario and perspectives for containing an increasing health problem von Guerra-Duarte, Clara, Saavedra-Langer, Rafael, Matavel, Alessandra, Oliveira-Mendes, Barbara B R, Chavez-Olortegui, Carlos, Paiva, Ana Luiza Bittencourt

Volltext

Cytotoxin antibody-based colourimetric sensor for field-level differential detection of elapid among big four snake venom von Kaul, Sherin, Sai Keerthana, L., Kumar, Pankaj, Birader, Komal, Tammineni, Yathirajarao, Rawat, Deepali, Suman, Pankaj

Volltext

A hidden deadly venomous insect: First eco-epidemiological assessment and risk mapping of lonomism in Argentina von Gisela Casafus, Milena, Melo Favalesso, Marilia, Andrea Gritti, Micaela, Manuel Coronel, Juan, Bittencourt Guimaraes, Ana Tereza, Elisa Peichoto, Maria

Volltext

Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping von Engmark, Mikael, Lomonte, Bruno, Gutiérrez, José María, Laustsen, Andreas H, De Masi, Federico, Andersen, Mikael R, Lund, Ole

Volltext

Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies von Fields, Conor, O'Connell, David, Xiao, Sujing, Lee, Gil U, Billiald, Philippe, Muzard, Julien

Volltext

Loxoscelism: Advances and Challenges in the Design of Antibody Fragments with Therapeutic Potential von Karim-Silva, Sabrina, Becker-Finco, Alessandra, Jiacomini, Isabella Gizzi, Boursin, Fanny, Leroy, Arnaud, Noiray, Magali, de Moura, Juliana, Aubrey, Nicolas, Billiald, Philippe, Alvarenga, Larissa M.

Volltext

Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion von Demeu, Lara Maria Kalempa, Soares, Rodrigo Jahn, Miranda, Juliana Severo, Pacheco-Lugo, Lisandro A, Oliveira, Kelin Gonçalves, Cortez Plaza, Cristian Andrés, Billiald, Philippe, Ferreira de Moura, Juliana, Yoshida, Nobuko, Alvarenga, Larissa Magalhães, DaRocha, Wanderson Duarte

Volltext

Engineering venom's toxin-neutralizing antibody fragments and its therapeutic potential von Alvarenga, Larissa M, Zahid, Muhammad, di Tommaso, Anne, Juste, Matthieu O, Aubrey, Nicolas, Billiald, Philippe, Muzard, Julien

Volltext

Non-invasive molecular imaging of fibrosis using a collagen-targeted peptidomimetic of the platelet collagen receptor glycoprotein VI von Muzard, Julien, Sarda-Mantel, Laure, Loyau, Stéphane, Meulemans, Alain, Louedec, Liliane, Bantsimba-Malanda, Claudie, Hervatin, Florence, Marchal-Somme, Joëlle, Michel, Jean Baptiste, Le Guludec, Dominique, Billiald, Philippe, Jandrot-Perrus, Martine

Volltext

Antibody Fragments Humanization: Beginning with the End in Mind von Aubrey, Nicolas, Billiald, Philippe

Volltext

Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab: First-in-Human Healthy Volunteer Trial von Voors-Pette, Christine, Lebozec, Kristell, Dogterom, Peter, Jullien, Laurie, Billiald, Philippe, Ferlan, Pauline, Renaud, Lionel, Favre-Bulle, Olivier, Avenard, Gilles, Machacek, Matthias, Plétan, Yannick, Jandrot-Perrus, Martine

Volltext

Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks von Lebozec, Kristell, Jandrot-Perrus, Martine, Avenard, Gilles, Favre-Bulle, Olivier, Billiald, Philippe

Volltext

Quality and cost assessment of a recombinant antibody fragment produced from mammalian, yeast and prokaryotic host cells: A case study prior to pharmaceutical development von Lebozec, Kristell, Jandrot-Perrus, Martine, Avenard, Gilles, Favre-Bulle, Olivier, Billiald, Philippe

Volltext

Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen‐Induced Platelet Aggregation von Renaud, Lionel, Lebozec, Kristell, Voors‐Pette, Christine, Dogterom, Peter, Billiald, Philippe, Jandrot Perrus, Martine, Pletan, Yannick, Machacek, Matthias

Volltext