An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine‐56 von Pettinger, Jonathan, Le Bihan, Yann‐Vaï, Widya, Marcella, van Montfort, Rob L. M., Jones, Keith, Cheeseman, Matthew D.

Volltext

Mechanical Stress Identification Method in Anisotropic Ferromagnetic Materials using Eddy Current Testing von Bouterfas, Safae, Le Bihan, Yann, Santandrea, Laurent, Daniel, Laurent

Volltext

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders von Bellenie, Benjamin R, Cheung, Kwai-Ming J, Varela, Ana, Pierrat, Olivier A, Collie, Gavin W, Box, Gary M, Bright, Michael D, Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J, Shetty, Kartika N, Carter, Michael, Davis, Owen A, Henley, Alan T, Innocenti, Paolo, Johnson, Louise D, Liu, Manjuan, de Klerk, Selby, Le Bihan, Yann-Vaï, Lloyd, Matthew G, McAndrew, P. Craig, Shehu, Erald, Talbot, Rachel, Woodward, Hannah L, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M, Raynaud, Florence I, Rossanese, Olivia W, Hoelder, Swen

Volltext

Optimal Coupler Topology for Dynamic Wireless Power Transfer for Electric Vehicle von Kadem, Karim, Bensetti, Mohamed, Le Bihan, Yann, Labouré, Eric, Debbou, Mustapha

Volltext

8‑Substituted Pyrido[3,4‑d]pyrimidin-4(3H)‑one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors von Bavetsias, Vassilios, Lanigan, Rachel M, Ruda, Gian Filippo, Atrash, Butrus, McLaughlin, Mark G, Tumber, Anthony, Mok, N. Yi, Le Bihan, Yann-Vaï, Dempster, Sally, Boxall, Katherine J, Jeganathan, Fiona, Hatch, Stephanie B, Savitsky, Pavel, Velupillai, Srikannathasan, Krojer, Tobias, England, Katherine S, Sejberg, Jimmy, Thai, Ching, Donovan, Adam, Pal, Akos, Scozzafava, Giuseppe, Bennett, James M, Kawamura, Akane, Johansson, Catrine, Szykowska, Aleksandra, Gileadi, Carina, Burgess-Brown, Nicola A, von Delft, Frank, Oppermann, Udo, Walters, Zoe, Shipley, Janet, Raynaud, Florence I, Westaway, Susan M, Prinjha, Rab K, Fedorov, Oleg, Burke, Rosemary, Schofield, Christopher J, Westwood, Isaac M, Bountra, Chas, Müller, Susanne, van Montfort, Rob L. M, Brennan, Paul E, Blagg, Julian

Volltext

Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors von Davis, Owen A., Cheung, Kwai-Ming J., Brennan, Alfie, Lloyd, Matthew G., Rodrigues, Matthew J., Pierrat, Olivier A., Collie, Gavin W., Le Bihan, Yann-Vaï, Huckvale, Rosemary, Harnden, Alice C., Varela, Ana, Bright, Michael D., Eve, Paul, Hayes, Angela, Henley, Alan T., Carter, Michael D., McAndrew, P. Craig, Talbot, Rachel, Burke, Rosemary, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Meniconi, Mirco, Bellenie, Benjamin R., Hoelder, Swen

Volltext

Comparison of Coupling Coils for Static Inductive Power-Transfer Systems Taking into Account Sources of Uncertainty von Pei, Yao, Le Bihan, Yann, Bensetti, Mohamed, Pichon, Lionel

Volltext

Toward a Calculable Standard Shunt for Current Measurements at 10 A and Up To 1 MHz von Ouameur, Mohamed, Ziade, Francois, Bihan, Yann Le

Volltext

Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones von Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

Volltext

Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket von Lloyd, Matthew G, Huckvale, Rosemary, Cheung, Kwai-Ming J, Rodrigues, Matthew J, Collie, Gavin W, Pierrat, Olivier A, Gatti Iou, Mahad, Carter, Michael, Davis, Owen A, McAndrew, P. Craig, Gunnell, Emma, Le Bihan, Yann-Vaï, Talbot, Rachel, Henley, Alan T, Johnson, Louise D, Hayes, Angela, Bright, Michael D, Raynaud, Florence I, Meniconi, Mirco, Burke, Rosemary, van Montfort, Rob L. M, Rossanese, Olivia W, Bellenie, Benjamin R, Hoelder, Swen

Volltext

AN EFFICIENT METHOD FOR DIMENSIONING MAGNETIC SHIELDING FOR AN INDUCTION ELECTRIC VEHICLE CHARGING SYSTEM von Kadem, Karim, Benyoubi, Fethi, Bensetti, Mohamed, Bihan, Yann Le, Laboure, Eric, Debbou, Mustapha

Volltext

Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo von Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

Volltext

Structural and functional characterisation of human RNA helicase DHX8 provides insights into the mechanism of RNA-stimulated ADP release von Felisberto-Rodrigues, Catarina, Thomas, Jemima C, McAndrew, Craig, Le Bihan, Yann-Vaï, Burke, Rosemary, Workman, Paul, van Montfort, Rob L M

Volltext

Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70 von O'Connor, Suzanne, Le Bihan, Yann-Vaï, Westwood, Isaac M, Liu, Manjuan, Mak, Oi Wei, Zazeri, Gabriel, Povinelli, Ana P R, Jones, Alan M, van Montfort, Rob, Reynisson, Jóhannes, Collins, Ian

Volltext

Planar Omnidirectional Detection of RFID/NFC Patches Inside a Cubic Structure von Sun, Jie, Diet, Antoine, Bihan, Yann Le, Biancheri-Astier, Marc, Gannouni, Chadi, Police, Michel

Volltext

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (K... von Le Bihan, Yann-Vaï, Lanigan, Rachel M., Atrash, Butrus, McLaughlin, Mark G., Velupillai, Srikannathasan, Malcolm, Andrew G., England, Katherine S., Ruda, Gian Filippo, Mok, N. Yi, Tumber, Anthony, Tomlin, Kathy, Saville, Harry, Shehu, Erald, McAndrew, Craig, Carmichael, LeAnne, Bennett, James M., Jeganathan, Fiona, Eve, Paul, Donovan, Adam, Hayes, Angela, Wood, Francesca, Raynaud, Florence I., Fedorov, Oleg, Brennan, Paul E., Burke, Rosemary, van Montfort, Rob L.M., Rossanese, Olivia W., Blagg, Julian, Bavetsias, Vassilios

Volltext

A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity von Habib Bouguenina, Scarpino, Andrea, O'Hanlon, Jack A, Warne, Justin, Wang, Hannah Z, Laura Chan Wah Hak, Sadok, Amine, McAndrew, P Craig, Stubbs, Mark, Pierrat, Olivier A, Hahner, Tamas, Cabry, Marc P, Yann‐Vaï Le Bihan, Mitsopoulos, Costas, Sialana, Fernando J, Roumeliotis, Theodoros I, Burke, Rosemary, Rob L M van Montfort, Choudhari, Jyoti, Chopra, Rajesh, Caldwell, John J, Collins, Ian

Volltext

A higher-order entity formed by the flexible assembly of RAP1 with TRF2 von Gaullier, Guillaume, Miron, Simona, Pisano, Sabrina, Buisson, Rémi, Le Bihan, Yann-Vaï, Tellier-Lebègue, Carine, Messaoud, Wala, Roblin, Pierre, Guimarães, Beatriz G, Thai, Robert, Giraud-Panis, Marie-Josèphe, Gilson, Eric, Le Du, Marie-Hélène

Volltext

Uncertainty quantification in the design of wireless power transfer systems von Pei, Yao, Pichon, Lionel, Bensetti, Mohamed, Le-Bihan, Yann

Volltext

Privileged Structures and Polypharmacology within and between Protein Families von Meyers, Joshua, Chessum, Nicola E. A, Ali, Salyha, Mok, N. Yi, Wilding, Birgit, Pasqua, A. Elisa, Rowlands, Martin, Tucker, Michael J, Evans, Lindsay E, Rye, Carl S, O’Fee, Lisa, Le Bihan, Yann-Vaï, Burke, Rosemary, Carter, Michael, Workman, Paul, Blagg, Julian, Brown, Nathan, van Montfort, Rob L. M, Jones, Keith, Cheeseman, Matthew D

Volltext