Discovery of 7‑Oxo-2,4,5,7-tetrahydro‑6H‑pyrazolo[3,4‑c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibit... von Yoshikawa, Masato, Saitoh, Morihisa, Katoh, Taisuke, Seki, Tomohiro, Bigi, Simone V, Shimizu, Yuji, Ishii, Tsuyoshi, Okai, Takuro, Kuno, Masako, Hattori, Harumi, Watanabe, Etsuro, Saikatendu, Kumar S, Zou, Hua, Nakakariya, Masanori, Tatamiya, Takayuki, Nakada, Yoshihisa, Yogo, Takatoshi

Volltext

Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhib... von Yoshikawa, Masato, Saitoh, Morihisa, Katoh, Taisuke, Seki, Tomohiro, Bigi, Simone V, Shimizu, Yuji, Ishii, Tsuyoshi, Okai, Takuro, Kuno, Masako, Hattori, Harumi, Watanabe, Etsuro, Saikatendu, Kumar S, Zou, Hua, Nakakariya, Masanori, Tatamiya, Takayuki, Nakada, Yoshihisa, Yogo, Takatoshi

Volltext

Structural Biology in Drug Discovery and Development: Call for Papers von Heppner, David E, Bigi-Botterill, Simone V, Riley, Andrew P, Chibale, Kelly, Lindsley, Craig W

Volltext

Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure von Lanier, Marion, Pickens, Jason, Bigi, Simone V, Bradshaw-Pierce, Erica L, Chambers, Alison, Cheruvallath, Zacharia S, Cole, Derek, Dougan, Douglas R, Ermolieff, Jacques, Gibson, Tony, Halkowycz, Petro, Hirokawa, Aki, Ivetac, Anthony, Miura, Joanne, Nunez, Evan, Sabat, Mark, Tyhonas, John, Wang, Haixia, Wang, Xiaolun, Swann, Steve

Volltext

Fragment-based drug discovery of potent and selective MKK3/6 inhibitors von Adams, Mark, Kobayashi, Toshitake, Lawson, J. David, Saitoh, Morihisa, Shimokawa, Kenichiro, Bigi, Simone V., Hixon, Mark S., Smith, Christopher R., Tatamiya, Takayuki, Goto, Masayuki, Russo, Joseph, Grimshaw, Charles E., Swann, Steven

Volltext

Synthetic Approaches to the New Drugs Approved During 2020 von Flick, Andrew C., Leverett, Carolyn A., Ding, Hong X., McInturff, Emma L., Fink, Sarah J., Mahapatra, Subham, Carney, Daniel W., Lindsey, Erick A., DeForest, Jacob C., France, Scott P., Berritt, Simon, Bigi-Botterill, Simone V., Gibson, Tony S., Watson, Rebecca B., Liu, Yiyang, O’Donnell, Christopher J.

Volltext

Synthetic Approaches to the New Drugs Approved during 2019 von Flick, Andrew C, Leverett, Carolyn A, Ding, Hong X, McInturff, Emma, Fink, Sarah J, Mahapatra, Subham, Carney, Daniel W, Lindsey, Erick A, DeForest, Jacob C, France, Scott P, Berritt, Simon, Bigi-Botterill, Simone V, Gibson, Tony S, Liu, Yiyang, O’Donnell, Christopher J

Volltext

Design and Discovery of a Potent and Selective Inhibitor of Integrin αvβ1 von Sabat, Mark, Carney, Daniel W., Hernandez-Torres, Gloria, Gibson, Tony S., Balakrishna, Deepika, Zou, Hua, Xu, Rui, Chen, Chien-Hung, de Jong, Ron, Dougan, Douglas R., Qin, Ling, Bigi-Botterill, Simone V., Chambers, Alison, Miura, Joanne, Johnson, Lucas K., Ermolieff, Jacques, Johns, Deidre, Selimkhanov, Jangir, Kwok, Lily, DeMent, Kevin, Proffitt, Chris, Vu, Phong, Lindsey, Erick A., Ivetac, Tony, Jennings, Andy, Wang, Haixia, Manam, Padma, Santos, Cipriano, Fullenwider, Cody, Manohar, Rohan, Flick, Andrew C.

Volltext

Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile von Bigi-Botterill, Simone V., Ivetac, Anthony, Bradshaw, Erica L., Cole, Derek, Dougan, Douglas R., Ermolieff, Jacques, Halkowycz, Petro, Johnson, Ben, McBride, Christopher, Pickens, Jason, Sabat, Mark, Swann, Steven

Volltext

Announcing the Early Career Board of ACS Medicinal Chemistry Letters von Baranczak, Aleksandra, Bigi-Botterill, Simone V, Borsari, Chiara, Dombrowski, Amanda W, Estrada, Michelle A, Farrell, Mark P, Riley, Andrew P, Woodland, John G

Volltext

Correction to “Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure” von Lanier, Marion, Pickens, Jason, Bigi, Simone V, Bradshaw-Pierce, Erica L, Chambers, Alison, Cheruvallath, Zacharia S, Cole, Derek, Dougan, Douglas R, Ermolieff, Jacques, Gibson, Tony, Halkowycz, Petro, Hirokawa, Aki, Ivetac, Anthony, McBride, Christopher, Miura, Joanne, Nunez, Evan, Sabat, Mark, Tyhonas, John, Wang, Haixia, Wang, Xiaolun, Swann, Steve

Volltext

In This Issue, Volume 15, Issue 10 von Bigi-Botterill, Simone V.

Volltext

Structural Biology in Drug Discovery and Development: Call for Papers von Heppner, David E., Bigi-Botterill, Simone V., Riley, Andrew P., Chibale, Kelly, Lindsley, Craig W.

Volltext

Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp 3 character and an exquisite selectivity profile von Bigi-Botterill, Simone V, Ivetac, Anthony, Bradshaw, Erica L, Cole, Derek, Dougan, Douglas R, Ermolieff, Jacques, Halkowycz, Petro, Johnson, Ben, McBride, Christopher, Pickens, Jason, Sabat, Mark, Swann, Steven

Volltext

Mortality and prognostic factors in patients with bullous pemphigoid: a retrospective multicenter Italian study von Bardazzi, F., Filippi, F., Chessa, M.A., Iommi, M., Loi, C., Campanati, A., Rizzetto, G., Tagliati, C., Atzori, L., Muratori, S., Genovese, G., Gisondi, P., Schena, D., Balestri, R., Rech, G., Feliciani, C., Lasagni, C., Bigi, L., De Simone, C., Di Zenzo, G., Moro, F., Borghi, A., Di Lernia, V., D'Arrigo, G., Tripepi, G., Gori, M., Pitino, A.

Volltext

HETEROARYLAMIDE INHIBITORS OF TBK1 von VU, PHONG H, WOODHEAD, STEVEN JOHN, BIGI, SIMONE, KEUNG, WALTER, SWANN, STEVE, GANGLOFF, ANTHONY R

Volltext bestellen