Genetics of human origin and evolution: high-altitude adaptations von Bigham, Abigail W

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Human high-altitude adaptation: forward genetics meets the HIF pathway von Bigham, Abigail W, Lee, Frank S

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Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes von Tennessen, Jacob A., Bigham, Abigail W., O'Connor, Timothy D., Fu, Wenqing, Kenny, Eimear E., Gravel, Simon, McGee, Sean, Do, Ron, Liu, Xiaoming, Jun, Goo, Kang, Hyun Min, Jordan, Daniel, Leal, Suzanne M., Gabriel, Stacey, Rieder, Mark J., Abecasis, Goncalo, Altshuler, David, Nickerson, Deborah A., Boerwinkle, Eric, Sunyaev, Shamil, Bustamante, Carlos D., Bamshad, Michael J., Akey, Joshua M.

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Targeted capture and massively parallel sequencing of 12 human exomes von Ng, Sarah B, Shendure, Jay, Turner, Emily H, Robertson, Peggy D, Flygare, Steven D, Bigham, Abigail W, Lee, Choli, Shaffer, Tristan, Wong, Michelle, Bhattacharjee, Arindam, Eichler, Evan E, Bamshad, Michael, Nickerson, Deborah A

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Blood lead levels in Peruvian adults are associated with proximity to mining and DNA methylation von Childebayeva, Ainash, Goodrich, Jaclyn M., Chesterman, Nathan, Leon-Velarde, Fabiola, Rivera-Ch, Maria, Kiyamu, Melisa, Brutsaert, Tom D., Bigham, Abigail W., Dolinoy, Dana C.

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LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure von Childebayeva, Ainash, Jones, Tamara R., Goodrich, Jaclyn M., Leon-Velarde, Fabiola, Rivera-Chira, Maria, Kiyamu, Melisa, Brutsaert, Tom D., Dolinoy, Dana C., Bigham, Abigail W.

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Differential splenic responses to hyperoxic breathing at high altitude in Sherpa and lowlanders von Holmström, Pontus K., Harman, Taylor S., Kalker, Anne, Steiner, Bethany, Hawkins, Ella, Jorgensen, Kelsey C., Zhu, Kimberly T., Kunwar, Ajaya J., Thakur, Nilam, Dhungel, Sunil, Sherpa, Nima, Day, Trevor A., Schagatay, Erika K., Bigham, Abigail W., Brutsaert, Tom D.

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Genome-Wide DNA Methylation Changes Associated With High-Altitude Acclimatization During an Everest Base Camp Trek von Childebayeva, Ainash, Harman, Taylor, Weinstein, Julien, Day, Trevor, Brutsaert, Tom D., Bigham, Abigail W.

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Host genetic risk factors for West Nile virus infection and disease progression von Bigham, Abigail W, Buckingham, Kati J, Husain, Sofia, Emond, Mary J, Bofferding, Kathryn M, Gildersleeve, Heidi, Rutherford, Ann, Astakhova, Natalia M, Perelygin, Andrey A, Busch, Michael P, Murray, Kristy O, Sejvar, James J, Green, Sharone, Kriesel, John, Brinton, Margo A, Bamshad, Michael

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DNA Methylation Changes Are Associated With an Incremental Ascent to High Altitude von Childebayeva, Ainash, Harman, Taylor, Weinstein, Julien, Goodrich, Jaclyn M., Dolinoy, Dana C., Day, Trevor A., Bigham, Abigail W., Brutsaert, Tom D.

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Genome-Wide Epigenetic Signatures of Adaptive Developmental Plasticity in the Andes von Childebayeva, Ainash, Goodrich, Jaclyn M, Leon-Velarde, Fabiola, Rivera-Chira, Maria, Kiyamu, Melisa, Brutsaert, Tom D, Dolinoy, Dana C, Bigham, Abigail W

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A Genomewide Admixture Mapping Panel for Hispanic/Latino Populations von Mao, Xianyun, Bigham, Abigail W., Mei, Rui, Gutierrez, Gerardo, Weiss, Ken M., Brutsaert, Tom D., Leon-Velarde, Fabiola, Moore, Lorna G., Vargas, Enrique, McKeigue, Paul M., Shriver, Mark D., Parra, Esteban J.

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Estimates of Continental Ancestry Vary Widely among Individuals with the Same mtDNA Haplogroup von Emery, Leslie S., Magnaye, Kevin M., Bigham, Abigail W., Akey, Joshua M., Bamshad, Michael J.

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Andean and Tibetan patterns of adaptation to high altitude von Bigham, Abigail W., Wilson, Megan J., Julian, Colleen G., Kiyamu, Melisa, Vargas, Enrique, Leon-Velarde, Fabiola, Rivera-Chira, Maria, Rodriquez, Carmelo, Browne, Vaughn A., Parra, Esteban, Brutsaert, Tom D., Moore, Lorna G., Shriver, Mark D.

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Identifying positive selection candidate loci for high-altitude adaptation in Andean populations von Bigham, Abigail W, Mao, Xianyun, Mei, Rui, Brutsaert, Tom, Wilson, Megan J, Julian, Colleen Glyde, Parra, Esteban J, Akey, Joshua M, Moore, Lorna G, Shriver, Mark D

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Exome sequencing as a tool for Mendelian disease gene discovery von Bamshad, Michael J, Shendure, Jay, Ng, Sarah B, Bigham, Abigail W, Tabor, Holly K, Emond, Mary J, Nickerson, Deborah A

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Human races are not like dog breeds: refuting a racist analogy von Norton, Heather L., Quillen, Ellen E., Bigham, Abigail W., Pearson, Laurel N., Dunsworth, Holly

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High-altitude deer mouse hypoxia-inducible factor-2α shows defective interaction with CREB-binding protein von Song, Daisheng, Bigham, Abigail W., Lee, Frank S.

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Identifying adaptive alleles in the human genome: from selection mapping to functional validation von Werren, Elizabeth A., Garcia, Obed, Bigham, Abigail W.

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Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude von Brutsaert, Tom D., Kiyamu, Melisa, Revollendo, Gianpietro Elias, Isherwood, Jenna L., Lee, Frank S., Rivera-Ch, Maria, Leon-Velarde, Fabiola, Ghosh, Sudipta, Bigham, Abigail W.

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