Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes von Laybutt, D. R, Preston, A. M, Åkerfeldt, M. C, Kench, J. G, Busch, A. K, Biankin, A. V, Biden, T. J

Volltext

Reduced endoplasmic reticulum (ER)-to-Golgi protein trafficking contributes to ER stress in lipotoxic mouse beta cells by promoting protein overload von Preston, A. M, Gurisik, E, Bartley, C, Laybutt, D. R, Biden, T. J

Volltext

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1 von Ferdaoussi, M., Bergeron, V., Zarrouki, B., Kolic, J., Cantley, J., Fielitz, J., Olson, E. N., Prentki, M., Biden, T., MacDonald, P. E., Poitout, V.

Volltext

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells von Chan, J. Y., Cooney, G. J., Biden, T. J., Laybutt, D. R.

Volltext

Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets von Chan, J. Y., Biden, T. J., Laybutt, D. R.

Volltext

Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice von Raddatz, K., Turner, N., Frangioudakis, G., Liao, B. M., Pedersen, D. J., Cantley, J., Wilks, D., Preston, E., Hegarty, B. D., Leitges, M., Raftery, M. J., Biden, T. J., Schmitz-Peiffer, C.

Volltext

Cross-talk between the unfolded protein response and nuclear factor-[kappa]B signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets von Chan, J Y, Biden, T J, Laybutt, D R

Volltext

Diverse roles for protein kinase C δ and protein kinase C ε in the generation of high-fat-diet-induced glucose intolerance in mice: regulation of lipogenesis by protein kinase C δ... von Frangioudakis, G, Burchfield, J. G, Narasimhan, S, Cooney, G. J, Leitges, M, Biden, T. J, Schmitz-Peiffer, C

Volltext

Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells von McCloy, R A, Shelley, E J, Roberts, C G, Boslem, E, Biden, T J, Nicholson, R I, Gee, J M, Sutherland, R L, Musgrove, E A, Burgess, A, Butt, A J

Volltext

Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo von Cantley, J, Boslem, E, Laybutt, D. R, Cordery, D. V, Pearson, G, Carpenter, L, Leitges, M, Biden, T. J

Volltext

Ceramide Generation Is Sufficient to Account for the Inhibition of the Insulin-stimulated PKB Pathway in C2C12 Skeletal Muscle Cells Pretreated with Palmitate von Schmitz-Peiffer, Carsten, Craig, Denby L., Biden, Trevor J.

Volltext

Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle von Cazzolli, R, Mitchell, T. W, Burchfield, J. G, Pedersen, D. J, Turner, N, Biden, T. J, Schmitz-Peiffer, C

Volltext

Protein Kinase Cδ Activation by Interleukin-1β Stabilizes Inducible Nitric-oxide Synthase mRNA in Pancreatic β-Cells von Carpenter, Lee, Cordery, Damien, Biden, Trevor J.

Volltext

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice von Cooney, Gregory J, Lyons, Ruth J, Crew, A Jayne, Jensen, Thomas E, Molero, Juan Carlos, Mitchell, Christopher J, Biden, Trevor J, Ormandy, Christopher J, James, David E, Daly, Roger J

Volltext

Quantitative and functional characterization of muscarinic receptor subtypes in insulin-secreting cell lines and rat pancreatic islets von Iismaa, T P, Kerr, E A, Wilson, J R, Carpenter, L, Sims, N, Biden, T J

Volltext

Inhibition of PKCα induces a PKCδ-dependent apoptotic program in salivary epithelial cells von Matassa, A A, Kalkofen, R L, Carpenter, L, Biden, T J, Reyland, M E

Volltext

Protein Kinase Cι Activity Is Necessary for Bcr-Abl-mediated Resistance to Drug-induced Apoptosis von Jamieson, Lee, Carpenter, Lee, Biden, Trevor J., Fields, Alan P.

Volltext

Muscle lipid accumulation and protein kinase C activation in the insulin-resistant chronically glucose-infused rat von Laybutt, D. Ross, Schmitz-Peiffer, Carsten, Saha, Asish K, Ruderman, Neil B, Biden, Trevor J, Kraegen, Edward W

Volltext

Inhibition of glycogen synthesis by fatty acid in C2C12 muscle cells is independent of PKC-alpha , -epsilon , and -theta von Cazzolli, R, Craig, D. L, Biden, T. J, Schmitz-Peiffer, C

Volltext

G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1 von FERDAOUSSI, M, BERGERON, V, POITOUT, V, ZARROUKI, B, KOLIC, J, CANTLEY, J, FIELITZ, J, OLSON, E. N, PRENTKI, M, BIDEN, T, MACDONALD, P. E

Volltext