Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages von Bibby, M.C.

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50 Years of Preclinical Anticancer Drug Screening: Empirical to Target-Driven Approaches von SUGGITT, Marie, BIBBY, Michael C

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Differentiation and Definition of Vascular-Targeted Therapies von SIEMANN, Dietmar W, BIBBY, Michael C, DARK, Graham G, DICKER, Adam P, ESKENS, Ferry A. L. M, HORSMAN, Michael R, MARME, Dieter, LORUSSO, Patricia M

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In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazoles von Leong, Chee Onn, Suggitt, Marie, Swaine, David J, Bibby, Michael C, Stevens, Malcolm F G, Bradshaw, Tracey D

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In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug von Grosios, K, Holwell, S E, McGown, A T, Pettit, G R, Bibby, M C

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Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo von Leong, C-O, Gaskell, M, Martin, E A, Heydon, R T, Farmer, P B, Bibby, M C, Cooper, P A, Double, J A, Bradshaw, T D, Stevens, M F G

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Comparative Preclinical Pharmacokinetic and Metabolic Studies of the Combretastatin Prodrugs Combretastatin A4 Phosphate and A1 Phosphate von KIRWAN, Ian G, LOADMAN, Paul M, SWAINE, David J, ANTHONEY, D. Alan, PETTIT, George R, LIPPERT, John W, SHNYDER, Steve D, COOPER, Patricia A, BIBBY, Mike C

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Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles von Bradshaw, Tracey D, Bibby, Michael C, Double, John A, Fichtner, Iduna, Cooper, Patricia A, Alley, Michael C, Donohue, Susan, Stinson, Sherman F, Tomaszewjski, Joseph E, Sausville, Edward A, Stevens, Malcolm F G

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Antineoplastic agents. 509. Synthesis of fluorcombstatin phosphate and related 3-halostilbenes von Pettit, G.R, Minardi, M.D, Rosenberg, H.J, Hamel, E, Bibby, M.C, Martin, S.W, Jung, M.K, Pettit, R.K, Cuthbertson, T.J, Chapuis, J.C

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In-vitro cytotoxic activities of the major bromophenols of the red alga Polysiphonia lanosa and some novel synthetic isomers von Shoeib, N.A, Bibby, M.C, Blunden, G, Linley, P.A, Swaine, D.J, Wheelhouse, R.T, Wright, C.W

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MMP-10 Is Overexpressed, Proteolytically Active, and a Potential Target for Therapeutic Intervention in Human Lung Carcinomas von Gill, Jason H., Kirwan, Ian G., Seargent, Jill M., Martin, Sandie W., Tijani, Sidiq, Anikin, Vladimir A., Mearns, Alan J., Bibby, Michael C., Anthoney, Alan, Loadman, Paul M.

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Anti-vascular effects of vinflunine in the MAC 15A transplantable adenocarcinoma model von Holwell, S E, Hill, B T, Bibby, M C

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Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid von Laws, AL, Matthew, AM, Double, JA, Bibby, MC

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Antimicrobial activity of cecropins von Moore, Alison J., Beazley, Wayne D., Bibby, Michael C., Devine, Deirdre A.

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Enhancement of chemotherapy and radiotherapy of murine tumours by AQ4N, a bioreductively activated anti-tumour agent von Patterson, L H, McKeown, S R, Ruparelia, K, Double, J A, Bibby, M C, Cole, S, Stratford, I J

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Characterization of the Hollow Fiber Assay for the Determination of Microtubule Disruption In vivo von SUGGITT, Marie, SWAINE, David J, PETTIT, George R, BIBBY, Michael C

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Reducing the Cost of Screening Novel Agents Using the Hollow Fibre Assay von SHNYDER, S. D, COOPER, P. A, SCALLY, A. J, BIBBY, M. C

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Pharmacological approach towards the development of indolequinone bioreductive drugs based on the clinically inactive agent EO9 von Loadman, P M, Bibby, M C, Phillips, R M

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Expression of matrix metalloproteinase-10 in human bladder transitional cell carcinoma von Seargent, Jill M., Loadman, Paul M., Martin, Sandie W., Naylor, Brian, Bibby, Michael C., Gill, Jason H.

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Development of a Modified Hollow Fibre Assay for Studying Agents Targeting the Tumour Neovasculature von SHNYDER, S. D, HASAN, J, COOPER, P. A, PILARINOU, E, JUBB, E, JAYSON, G. C, BIBBY, M. C

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