Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis von Mehta, Arpan R., Gregory, Jenna M., Dando, Owen, Carter, Roderick N., Burr, Karen, Nanda, Jyoti, Story, David, McDade, Karina, Smith, Colin, Morton, Nicholas M., Mahad, Don J., Hardingham, Giles E., Chandran, Siddharthan, Selvaraj, Bhuvaneish T.

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Mutant C9orf72 human iPSC‐derived astrocytes cause non‐cell autonomous motor neuron pathophysiology von Zhao, Chen, Devlin, Anna‐Claire, Chouhan, Amit K., Selvaraj, Bhuvaneish T., Stavrou, Maria, Burr, Karen, Brivio, Veronica, He, Xin, Mehta, Arpan R., Story, David, Shaw, Christopher E., Dando, Owen, Hardingham, Giles E., Miles, Gareth B., Chandran, Siddharthan

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Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain von Gregory, Jenna M, Livesey, Matthew R, McDade, Karina, Selvaraj, Bhuvaneish T, Barton, Samantha K, Chandran, Siddharthan, Smith, Colin

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Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy von Hutchings, Amy-Jayne, Hambrecht, Bita, Veh, Alexander, Giridhar, Neha Jadhav, Zare, Abdolhossein, Angerer, Christina, Ohnesorge, Thorben, Schenke, Maren, Selvaraj, Bhuvaneish T., Chandran, Siddharthan, Sterneckert, Jared, Petri, Susanne, Seeger, Bettina, Briese, Michael, Stigloher, Christian, Bischler, Thorsten, Hermann, Andreas, Damme, Markus, Sendtner, Michael, Lüningschrör, Patrick

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Astrocytes mediate cell non-autonomous correction of aberrant firing in human FXS neurons von Sharma, Shreya Das, Reddy, Bharath Kumar, Pal, Rakhi, Ritakari, Tuula E., Cooper, James D., Selvaraj, Bhuvaneish T., Kind, Peter C., Chandran, Siddharthan, Wyllie, David J.A., Chattarji, Sumantra

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Maturation and electrophysiological properties of human pluripotent stem cell‐derived oligodendrocytes von Livesey, Matthew R., Magnani, Dario, Cleary, Elaine M., Vasistha, Navneet A., James, Owain T., Selvaraj, Bhuvaneish T., Burr, Karen, Story, David, Shaw, Christopher E., Kind, Peter C., Hardingham, Giles E., Wyllie, David J.A., Chandran, Siddharthan

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Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction von Perkins, Emma M, Burr, Karen, Banerjee, Poulomi, Mehta, Arpan R, Dando, Owen, Selvaraj, Bhuvaneish T, Suminaite, Daumante, Nanda, Jyoti, Henstridge, Christopher M, Gillingwater, Thomas H, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan, Livesey, Matthew R

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The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling von Schembs, Leah, Willems, Ariane, Hasenpusch-Theil, Kerstin, Cooper, James D., Whiting, Katie, Burr, Karen, Bøstrand, Sunniva M.K., Selvaraj, Bhuvaneish T., Chandran, Siddharthan, Theil, Thomas

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A 3D cell culture system for bioengineering human neuromuscular junctions to model ALS von Massih, Bita, Veh, Alexander, Schenke, Maren, Mungwa, Simon, Seeger, Bettina, Selvaraj, Bhuvaneish T, Chandran, Siddharthan, Reinhardt, Peter, Sterneckert, Jared, Hermann, Andreas, Sendtner, Michael, Lüningschrör, Patrick

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40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology? von Ng Kee Kwong, Koy Chong, Harbham, Pratap K, Selvaraj, Bhuvaneish T, Gregory, Jenna M, Pal, Suvankar, Hardingham, Giles E, Chandran, Siddharthan, Mehta, Arpan R

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Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus von Wong, Charis, Gregory, Jenna M, Liao, Jing, Egan, Kieren, Vesterinen, Hanna M, Ahmad Khan, Aimal, Anwar, Maarij, Beagan, Caitlin, Brown, Fraser S, Cafferkey, John, Cardinali, Alessandra, Chiam, Jane Yi, Chiang, Claire, Collins, Victoria, Dormido, Joyce, Elliott, Elizabeth, Foley, Peter, Foo, Yu Cheng, Fulton-Humble, Lily, Gane, Angus B, Glasmacher, Stella A, Heffernan, Áine, Jayaprakash, Kiran, Jayasuriya, Nimesh, Kaddouri, Amina, Kiernan, Jamie, Langlands, Gavin, Leighton, D, Liu, Jiaming, Lyon, James, Mehta, Arpan R, Meng, Alyssa, Nguyen, Vivienne, Park, Na Hyun, Quigley, Suzanne, Rashid, Yousuf, Salzinger, Andrea, Shiell, Bethany, Singh, Ankur, Soane, Tim, Thompson, Alexandra, Tomala, Olaf, Waldron, Fergal M, Selvaraj, Bhuvaneish T, Chataway, Jeremy, Swingler, Robert, Connick, Peter, Pal, Suvankar, Chandran, Siddharthan, Macleod, Malcolm

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Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis von Barton, Samantha K, Gregory, Jenna M, Selvaraj, Bhuvaneish T, McDade, Karina, Henstridge, Christopher M, Spires-Jones, Tara L, James, Owen G, Mehta, Arpan R, Story, David, Burr, Karen, Magnani, Dario, Isaacs, Adrian M, Smith, Colin, Chandran, Siddharthan

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Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns von Das Sharma, Shreya, Pal, Rakhi, Reddy, Bharath Kumar, Selvaraj, Bhuvaneish T, Raj, Nisha, Samaga, Krishna Kumar, Srinivasan, Durga J, Ornelas, Loren, Sareen, Dhruv, Livesey, Matthew R, Bassell, Gary J, Svendsen, Clive N, Kind, Peter C, Chandran, Siddharthan, Chattarji, Sumantra, Wyllie, David J A

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Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936 von Toombs, Jamie, Panther, Lindsay, Ornelas, Loren, Liu, Chunyan, Gomez, Emilda, Martín-Ibáñez, Raquel, Cox, Simon R., Ritchie, Stuart J., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Russ, Tom C., Murphy, Lee, Cooper, James D., Burr, Karen, Selvaraj, Bhuvaneish T., Browne, Cathy, Svendsen, Clive N., Cowley, Sally A., Deary, Ian J., Chandran, Siddharthan, Spires-Jones, Tara L., Sareen, Dhruv

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Blood-CNS barrier dysfunction in amyotrophic lateral sclerosis: Proposed mechanisms and clinical implications von Steinruecke, Moritz, Lonergan, Rebecca Murphy, Selvaraj, Bhuvaneish T, Chandran, Siddharthan, Diaz-Castro, Blanca, Stavrou, Maria

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Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons von Qiu, Jing, McQueen, Jamie, Bilican, Bilada, Dando, Owen, Magnani, Dario, Punovuori, Karolina, Selvaraj, Bhuvaneish T, Livesey, Matthew, Haghi, Ghazal, Heron, Samuel, Burr, Karen, Patani, Rickie, Rajan, Rinku, Sheppard, Olivia, Kind, Peter C, Simpson, T Ian, Tybulewicz, Victor Lj, Wyllie, David Ja, Fisher, Elizabeth Mc, Lowell, Sally, Chandran, Siddharthan, Hardingham, Giles E

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Role of glia in delirium: proposed mechanisms and translational implications von Heffernan, Áine Bríd, Steinruecke, Moritz, Dempsey, Georgia, Chandran, Siddharthan, Selvaraj, Bhuvaneish T, Jiwaji, Zoeb, Stavrou, Maria

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Assessment of Mitochondrial Trafficking as a Surrogate for Fast Axonal Transport in Human Induced Pluripotent Stem Cell–Derived Spinal Motor Neurons von Mehta, Arpan R., Chandran, Siddharthan, Selvaraj, Bhuvaneish T.

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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia von Prudencio, Mercedes, Humphrey, Jack, Pickles, Sarah, Brown, Anna-Leigh, Hill, Sarah E, Kachergus, Jennifer M, Shi, J, Heckman, Michael G, Spiegel, Matthew R, Cook, Casey, Song, Yuping, Yue, Mei, Daughrity, Lillian M, Carlomagno, Yari, Jansen-West, Karen, de Castro, Cristhoper Fernandez, DeTure, Michael, Koga, Shunsuke, Wang, Ying-Chih, Sivakumar, Prasanth, Bodo, Cristian, Candalija, Ana, Talbot, Kevin, Selvaraj, Bhuvaneish T, Burr, Karen, Chandran, Siddharthan, Newcombe, Jia, Lashley, Tammaryn, Hubbard, Isabel, Catalano, Demetra, Kim, Duyang, Propp, Nadia, Fennessey, Samantha, Fagegaltier, Delphine, Phatnani, Hemali, Secrier, Maria, Fisher, Elizabeth Mc, Oskarsson, Björn, van Blitterswijk, Marka, Rademakers, Rosa, Graff-Radford, Neil R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Josephs, Keith A, Thompson, E Aubrey, Raj, Towfique, Ward, Michael, Dickson, Dennis W, Gendron, Tania F, Fratta, Pietro, Petrucelli, Leonard

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iPSC-derived myelinoids to study myelin biology of humans von James, Owen G., Selvaraj, Bhuvaneish T., Magnani, Dario, Burr, Karen, Connick, Peter, Barton, Samantha K., Vasistha, Navneet A., Hampton, David W., Story, David, Smigiel, Robert, Ploski, Rafal, Brophy, Peter J., ffrench-Constant, Charles, Lyons, David A., Chandran, Siddharthan

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