The Pharmacology of T Cell Therapies von Milone, Michael C, Bhoj, Vijay G

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CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy von Pillai, Vinodh, Muralidharan, Kavitha, Meng, Wenzhao, Bagashev, Asen, Oldridge, Derek A., Rosenthal, Jaclyn, Van Arnam, John, Melenhorst, Jos J., Mohan, Diwakar, DiNofia, Amanda M., Luo, Minjie, Cherian, Sindhu, Fromm, Jonathan R., Wertheim, Gerald, Thomas-Tikhonenko, Andrei, Paessler, Michele, June, Carl H., Luning Prak, Eline T., Bhoj, Vijay G., Grupp, Stephan A., Maude, Shannon L., Rheingold, Susan R.

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MAVS and MyD88 Are Essential for Innate Immunity but Not Cytotoxic T Lymphocyte Response against Respiratory Syncytial Virus von Bhoj, Vijay G., Sun, Qinmiao, Bhoj, Elizabeth J., Somers, Cynthia, Chen, Xiang, Torres, Juan-Pablo, Mejias, Asuncion, Gomez, Ana M., Jafri, Hasan, Ramilo, Octavio, Chen, Zhijian J.

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On the road to eliminating long‐lived plasma cells—“are we there yet?” von Markmann, Caroline, Bhoj, Vijay G.

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Ubiquitylation in innate and adaptive immunity von Bhoj, Vijay G, Chen, Zhijian J

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Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease von Ellebrecht, Christoph T., Bhoj, Vijay G., Nace, Arben, Choi, Eun Jung, Mao, Xuming, Cho, Michael Jeffrey, Di Zenzo, Giovanni, Lanzavecchia, Antonio, Seykora, John T., Cotsarelis, George, Milone, Michael C., Payne, Aimee S.

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Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4 von Bhoj, Vijay G., Li, Lucy, Parvathaneni, Kalpana, Zhang, Zheng, Kacir, Stephen, Arhontoulis, Dimitrios, Zhou, Kenneth, McGettigan-Croce, Bevin, Nunez-Cruz, Selene, Gulendran, Gayathri, Boesteanu, Alina C., Johnson, Laura, Feldman, Michael D., Radaelli, Enrico, Mansfield, Keith, Nasrallah, MacLean, Goydel, Rebecca S., Peng, Haiyong, Rader, Christoph, Milone, Michael C., Siegel, Don L.

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Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies von Parker, Kevin R., Migliorini, Denis, Perkey, Eric, Yost, Kathryn E., Bhaduri, Aparna, Bagga, Puneet, Haris, Mohammad, Wilson, Neil E., Liu, Fang, Gabunia, Khatuna, Scholler, John, Montine, Thomas J., Bhoj, Vijay G., Reddy, Ravinder, Mohan, Suyash, Maillard, Ivan, Kriegstein, Arnold R., June, Carl H., Chang, Howard Y., Posey, Avery D., Satpathy, Ansuman T.

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Therapeutic Opportunities for Immunoreceptor-Engineered T Cell Therapy for Modulation of Alloimmunity von Muralidharan, Kavitha, Agarwal, Divyansh, Naji, Ali, Bhoj, Vijay G

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Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell von Ruella, Marco, Xu, Jun, Barrett, David M., Fraietta, Joseph A., Reich, Tyler J., Ambrose, David E., Klichinsky, Michael, Shestova, Olga, Patel, Prachi R., Kulikovskaya, Irina, Nazimuddin, Farzana, Bhoj, Vijay G., Orlando, Elena J., Fry, Terry J., Bitter, Hans, Maude, Shannon L., Levine, Bruce L., Nobles, Christopher L., Bushman, Frederic D., Young, Regina M., Scholler, John, Gill, Saar I., June, Carl H., Grupp, Stephan A., Lacey, Simon F., Melenhorst, J. Joseph

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Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders von Baglaenko, Yuriy, Wagner, Catriona, Bhoj, Vijay G, Brodin, Petter, Gershwin, M Eric, Graham, Daniel, Invernizzi, Pietro, Kidd, Kenneth K, Korsunsky, Ilya, Levy, Michael, Mammen, Andrew L, Nizet, Victor, Ramirez-Valle, Francisco, Stites, Edward C, Williams, Marc S, Wilson, Michael, Rose, Noel R, Ladd, Virginia, Sirota, Marina

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Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy von Bhoj, Vijay G., Arhontoulis, Dimitrios, Wertheim, Gerald, Capobianchi, James, Callahan, Colleen A., Ellebrecht, Christoph T., Obstfeld, Amrom E., Lacey, Simon F., Melenhorst, Jan J., Nazimuddin, Farzana, Hwang, Wei-Ting, Maude, Shannon L., Wasik, Mariusz A., Bagg, Adam, Schuster, Stephen, Feldman, Michael D., Porter, David L., Grupp, Stephen A., June, Carl H., Milone, Michael C.

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Respiratory Syncytial Virus Persistence in the Lungs Correlates with Airway Hyperreactivity in the Mouse Model von Estripeaut, Dora, Torres, Juan Pablo, Somers, Cynthia S., Tagliabue, Claudia, Khokhar, Shama, Bhoj, Vijay G., Grube, Steve M., Wozniakowski, Aneta, Gomez, Ana M., Ramilo, Octavio, Jafri, Hasan S., Mejias, Asuncion

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BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia von Kong, Weimin, Dimitri, Alexander, Wang, Wenliang, Jung, In-Young, Ott, Christopher J., Fasolino, Maria, Wang, Yan, Kulikovskaya, Irina, Gupta, Minnal, Yoder, Todd, DeNizio, Jamie E., Everett, John K., Williams, Erik F., Xu, Jun, Scholler, John, Reich, Tyler J., Bhoj, Vijay G., Haines, Kathleen M., Maus, Marcela, Melenhorst, J. Joseph, Young, Regina M., Jadlowsky, Julie K., Marcucci, Katherine T., Bradner, James E., Levine, Bruce L., Porter, David L., Bushman, Frederic D., Kohli, Rahul M., June, Carl H., Davis, Megan M., Lacey, Simon F., Vahedi, Golnaz, Fraietta, Joseph A.

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Conventional T cell therapies pave the way for novel Treg therapeutics von Li, Lucy Z., Zhang, Zheng, Bhoj, Vijay G.

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Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice von Torres, Juan Pablo, Gomez, Ana M, Khokhar, Shama, Bhoj, Vijay G, Tagliabue, Claudia, Chang, Michael L, Kiener, Peter A, Revell, Paula A, Ramilo, Octavio, Mejias, Asuncion

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Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse von Faude, Sophia, Wei, Jane, Muralidharan, Kavitha, Xu, Xiaoming, Wertheim, Gerald, Paessler, Michele, Bhoj, Vijay G., Grupp, Stephan A., Maude, Shannon L., Rheingold, Susan R., Pillai, Vinodh

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Lipoprotein Apheresis von Bhoj, Vijay G., Sachais, Bruce S

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Stable HLA antibodies following sustained CD19+ cell depletion implicate a long-lived plasma cell source von Zhang, Zheng, Schuster, Stephen J., Lacey, Simon F., Milone, Michael C., Monos, Dimitri, Bhoj, Vijay G.

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Immunotherapy targeting B cells and long-lived plasma cells effectively eliminates pre-existing donor-specific allo-antibodies von Zhang, Zheng, Markmann, Caroline, Yu, Ming, Agarwal, Divyansh, Rostami, Susan, Wang, Wei, Liu, Chengyang, Zhao, Huiwu, Ochoa, Trini, Parvathaneni, Kalpana, Xu, Xiaoming, Li, Eric, Gonzalez, Vanessa, Khadka, Roman, Hoffmann, Jennifer, Knox, James J, Scholler, John, Marcellus, Brooke, Allman, David, Fraietta, Joseph A, Samelson-Jones, Benjamin, Milone, Michael C, Monos, Dimitri, Garfall, Alfred L, Naji, Ali, Bhoj, Vijay G

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