Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: A 12-month follow-up analysis von Haldar, Pranabashis, MD, Brightling, Christopher E., PhD, Singapuri, Amisha, BSc, Hargadon, Beverley, BSc, Gupta, Sumit, PhD, Monteiro, William, BSc, Bradding, Peter, PhD, Green, Ruth H., MD, Wardlaw, Andrew J., PhD, Ortega, Hector, PhD, Pavord, Ian D., DM

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Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma von Haldar, Pranabashis, Brightling, Christopher E, Hargadon, Beverley, Gupta, Sumit, Monteiro, William, Sousa, Ana, Marshall, Richard P, Bradding, Peter, Green, Ruth H, Wardlaw, Andrew J, Pavord, Ian D

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Lung function decline and variable airway inflammatory pattern: Longitudinal analysis of severe asthma von Newby, Christopher, PhD, Agbetile, Joshua, MRCP, Hargadon, Beverley, RGN, Monteiro, Will, MSc, Green, Ruth, FRCP, MD, Pavord, Ian, FRCP, MD, Brightling, Christopher, FRCP, PhD, Siddiqui, Salman, MRCP, PhD

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Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma von Shikotra, Aarti, BSc, Choy, David F., BSc, Ohri, Chandra M., MD, Doran, Emma, BSc, Butler, Claire, MBBCh, Hargadon, Beverley, BSc, Shelley, Maria, BA, Abbas, Alexander R., PhD, Austin, Cary D., MD, PhD, Jackman, Janet, MSc, Wu, Lawren C., PhD, Heaney, Liam G., MD, Arron, Joseph R., MD, PhD, Bradding, Peter, DM

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Effectiveness of voriconazole in the treatment of Aspergillus fumigatus –associated asthma (EVITA3 study) von Agbetile, Joshua, MD, Bourne, Michelle, RGN, Fairs, Abbie, PhD, Hargadon, Beverley, RGN, Desai, Dhananjay, MD, Broad, Clare, Morley, Joseph, BSc, Bradding, Peter, DM, FRCP, Brightling, Christopher E., PhD, FRCP, Green, Ruth H., DM, FRCP, Haldar, Pranabashis, DM, MRCP, Pashley, Catherine H., PhD, Pavord, Ian D., DM, FRCP, Wardlaw, Andrew J., PhD, FRCP

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A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma von Shikotra, Aarti, Choy, David F, Siddiqui, Salman, Arthur, Greer, Nagarkar, Deepti R, Jia, Guiquan, Wright, Adam K A, Ohri, Chandra M, Doran, Emma, Butler, Claire A, Hargadon, Beverley, Abbas, Alexander R, Jackman, Janet, Wu, Lawren C, Heaney, Liam G, Arron, Joseph R, Bradding, Peter

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Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography-mass spectrometry von Ibrahim, Wadah, Cordell, Rebecca L., Wilde, Michael J., Richardson, Matthew, Carr, Liesl, Dasi, Ananga Sundari Devi, Hargadon, Beverley, Free, Robert C., Monks, Paul S., Brightling, Christopher E., Greening, Neil J., Siddiqui, Salman

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Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum von Ghebre, Michael A, Pang, Pee Hwee, Desai, Dhananjay, Hargadon, Beverley, Newby, Chris, Woods, Joanne, Rapley, Laura, Cohen, Suzanne E, Herath, Athula, Gaillard, Erol A, May, Richard D, Brightling, Chris E

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A cross-sectional study of patterns of airway dysfunction, symptoms and morbidity in primary care asthma von Shaw, Dominick, Green, Ruth, Berry, Mike, Mellor, Sarah, Hargadon, Beverley, Shelley, Maria, McKenna, Sue, Thomas, Mike, Pavord, Ian

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Lung Computational Models and the Role of the Small Airways in Asthma von Foy, Brody H, Soares, Marcia, Bordas, Rafel, Richardson, Matthew, Bell, Alex, Singapuri, Amisha, Hargadon, Beverley, Brightling, Christopher, Burrowes, Kelly, Kay, David, Owers-Bradley, John, Siddiqui, Salman

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Composite type-2 biomarker strategy versus a symptom–risk-based algorithm to adjust corticosteroid dose in patients with severe asthma: a multicentre, single-blind, parallel group,... von Heaney, Liam G, Busby, John, Hanratty, Catherine E, Djukanovic, Ratko, Woodcock, Ashley, Walker, Samantha M, Hardman, Timothy C, Arron, Joseph R, Choy, David F, Bradding, Peter, Brightling, Christopher E, Chaudhuri, Rekha, Cowan, Douglas C, Mansur, Adel H, Fowler, Stephen J, Niven, Robert M, Howarth, Peter H, Lordan, James L, Menzies-Gow, Andrew, Harrison, Tim W, Robinson, Douglas S, Holweg, Cecile T J, Matthews, John G, Pavord, Ian D, Adcock, Ian M, Azim, Adnam, Bellamy, Mary, Borg, Catherine, Bourne, Michelle, Connolly, Clare, Costello, Richard W, Corrigan, Chris J, Davies, Sarah, Davies, Gareth, Chung, Kian F, Gainsborough, Gabrielle, Grandison, Traceyanne, Hargadon, Beverley, Horn, Avril, Hudson, Val, Jackson, David, Johnston, Sebastian, Jones, Geraldine, McCourt, Paula, Nunez, Maria, Shaw, Dominic E, Smith, Katherine, Solis, Joel, Stone, Roisin, Yang, Freda

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COPD exacerbation severity and frequency is associated with impaired macrophage efferocytosis of eosinophils von Eltboli, Osama, Bafadhel, Mona, Hollins, Fay, Wright, Adam, Hargadon, Beverley, Kulkarni, Neeta, Brightling, Christopher

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IgE Sensitization to Aspergillus fumigatus Is Associated with Reduced Lung Function in Asthma von FAIRS, Abbie, AGBETILE, Joshua, PAVORD, Ian D, WARDLAW, Andrew J, PASHLEY, Catherine H, HARGADON, Beverley, BOURNE, Michelle, MONTEIRO, William R, BRIGHTLING, Christopher E, BRADDING, Peter, GREEN, Ruth H, MUTALITHAS, Kugathasan, DESAI, Dhananjay

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Evidence of a Role of Tumor Necrosis Factor α in Refractory Asthma von Berry, Mike A, Hargadon, Beverley, Shelley, Maria, Parker, Debbie, Shaw, Dominick E, Green, Ruth H, Bradding, Peter, Brightling, Christopher E, Wardlaw, Andrew J, Pavord, Ian D

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Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial von Green, Ruth H, Brightling, Christopher E, McKenna, Susan, Hargadon, Beverley, Parker, Debbie, Bradding, Peter, Wardlaw, Andrew J, Pavord, Ian D

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Exacerbations of severe asthma in patients treated with mepolizumab von Shrimanker, Rahul, Pavord, Ian D, Yancey, Steve, Heaney, Liam G, Green, Ruth H, Bradding, Peter, Hargadon, Beverley, Brightling, Chris E, Wardlaw, Andrew J, Haldar, Pranabashis

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Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis von Siddiqui, Salman, Shikotra, Aarti, Richardson, Matthew, Doran, Emma, Choy, David, Bell, Alex, Austin, Cary D., Eastham-Anderson, Jeffrey, Hargadon, Beverley, Arron, Joseph R., Wardlaw, Andrew, Brightling, Christopher E., Heaney, Liam G., Bradding, Peter

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The effects of inhaled corticosteroids on healthy airways von Marchi, Emanuele, Hinks, Timothy S. C., Richardson, Matthew, Khalfaoui, Latifa, Symon, Fiona A., Rajasekar, Poojitha, Clifford, Rachel, Hargadon, Beverley, Austin, Cary D., MacIsaac, Julia L., Kobor, Michael S., Siddiqui, Salman, Mar, Jordan S., Arron, Joseph R., Choy, David F., Bradding, Peter

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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma von Khalfaoui, Latifa, Symon, Fiona A., Couillard, Simon, Hargadon, Beverley, Chaudhuri, Rekha, Bicknell, Steve, Mansur, Adel H., Shrimanker, Rahul, Hinks, Timothy S. C., Pavord, Ian D., Fowler, Stephen J., Brown, Vanessa, McGarvey, Lorcan P., Heaney, Liam G., Austin, Cary D., Howarth, Peter H., Arron, Joseph R., Choy, David F., Bradding, Peter

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Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic Omalizumab in Severe Asthma in Adults: Results of the SoMOSA Study von Djukanovic, R, Brinkman, P, Kolmert, J, Gomez, C, Schofield, J, Brandsma, J, Shapanis, A, Skipp, PJS, Postle, A, Wheelock, C, Dahlen, SE, Sterk, PJ, Brown, T, Jackson, DJ, Mansur, A, Pavord, I, Patel, M, Brightling, C, Siddiqui, S, Bradding, P, Sabroe, I, Saralaya, D, Chishimba, L, Porter, J, Robinson, D, Fowler, S, Howarth, PH, Little, L, Oliver, T, Hill, K, Stanton, L, Allen, A, Ellis, D, Griffiths, G, Harrison, T, Akenroye, A, Lasky-Su, J, Heaney, L, Chaudhuri, R, Kurukulaaratchy, R

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