Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities von Blijlevens, Maxime, Li, Jing, van Beusechem, Victor W.

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A genome‐wide siRNA screen for regulators of tumor suppressor p53 activity in human non‐small cell lung cancer cells identifies components of the RNA splicing machinery as targets... von Siebring‐van Olst, Ellen, Blijlevens, Maxime, Menezes, Renee X., Meulen‐Muileman, Ida H., Smit, Egbert F., Beusechem, Victor W.

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Evaluation of a Novel Oncolytic Adenovirus Silencing SYVN1 von Vermeulen, Christie, Brachtlova, Tereza, Tol, Nikki, van der Meulen-Muileman, Ida H, Hodzic, Jasmina, van de Vrugt, Henri J, van Beusechem, Victor W

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High-throughput RNAi screening reveals cancer-selective lethal targets in the RNA spliceosome von Blijlevens, Maxime, van der Meulen-Muileman, Ida H., de Menezes, Renée X., Smit, Egbert F., van Beusechem, Victor W.

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High-Throughput Firefly Luciferase Reporter Assays von Siebring-van Olst, Ellen, van Beusechem, Victor W.

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Double-Stranded RNA Structural Elements Holding the Key to Translational Regulation in Cancer: The Case of Editing in RNA-Binding Motif Protein 8A von Abukar, Asra, Wipplinger, Martin, Hariharan, Ananya, Sun, Suna, Ronner, Manuel, Sculco, Marika, Okonska, Agata, Kresoja-Rakic, Jelena, Rehrauer, Hubert, Qi, Weihong, Beusechem, Victor W van, Felley-Bosco, Emanuela

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WEE1 inhibition sensitizes osteosarcoma to radiotherapy von PosthumaDeBoer, Jantine, Würdinger, Thomas, Graat, Harm C A, van Beusechem, Victor W, Helder, Marco N, van Royen, Barend J, Kaspers, Gertjan J L

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Human Non-Small Cell Lung Cancer-Chicken Embryo Chorioallantoic Membrane Tumor Models for Experimental Cancer Treatments von Li, Jing, Brachtlova, Tereza, van der Meulen-Muileman, Ida H, Kleerebezem, Stijn, Liu, Chang, Li, Peiyu, van Beusechem, Victor W

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Quantitative Virus-Associated RNA Detection to Monitor Oncolytic Adenovirus Replication von Brachtlova, Tereza, Li, Jing, van der Meulen-Muileman, Ida H, Sluiter, Femke, von Meijenfeldt, Willem, Witte, Isabella, Massaar, Sanne, van den Oever, Ruben, de Vrij, Jeroen, van Beusechem, Victor W

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Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition von van Harten, Anne M., de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Ganzevles, Sonja H., Hunter, Keith D., Leemans, C. René, van Beusechem, Victor W., Wolthuis, Rob M. F., de Menezes, Renée X., Brakenhoff, Ruud H.

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Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells von Blijlevens, Maxime, Komor, Malgorzata A, Sciarrillo, Rocco, Smit, Egbert F, Fijneman, Remond J A, van Beusechem, Victor W

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Functional Genetic Screens Identify Genes Essential for Tumor Cell Survival in Head and Neck and Lung Cancer von MARTENS-DE KEMP, Sanne R, NAGEL, Remco, STIGTER-VAN WALSUM, Marijke, VAN DER MEULEN, Ida H, VAN BEUSECHEM, Victor W, BRAAKHUIS, Boudewijn J. M, BRAKENHOFF, Ruud H

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Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1 von Cervera-Carrascon, Victor, Quixabeira, Dafne C A, Santos, Joao M, Havunen, Riikka, Milenova, Ioanna, Verhoeff, Jan, Heiniö, Camilla, Zafar, Sadia, Garcia-Vallejo, Juan J, van Beusechem, Victor W, de Gruijl, Tanja D, Kalervo, Aino, Sorsa, Suvi, Kanerva, Anna, Hemminki, Akseli

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Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 von Berenguer, Jordi, Lagerweij, Tonny, Zhao, Xi Wen, Dusoswa, Sophie, van der Stoop, Petra, Westerman, Bart, Gooijer, Mark C. de, Zoetemelk, Marloes, Zomer, Anoek, Crommentuijn, Matheus H. W., Wedekind, Laurine E., López-López, Àlan, Giovanazzi, Alberta, Bruch-Oms, Marina, Meulen-Muileman, Ida H. van der, Reijmers, Rogier M., van Kuppevelt, Toin H., García-Vallejo, Juan-Jesús, van Kooyk, Yvette, Tannous, Bakhos A., Wesseling, Pieter, Koppers-Lalic, Danijela, Vandertop, W. Peter, Noske, David P., van Beusechem, Victor W., van Rheenen, Jacco, Pegtel, D. Michiel, Tellingen, Olaf van, Wurdinger, Thomas

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The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics von Martens-de Kemp, Sanne R, Brink, Arjen, van der Meulen, Ida H, de Menezes, Renée X, Te Beest, Dennis E, Leemans, C René, van Beusechem, Victor W, Braakhuis, Boudewijn J M, Brakenhoff, Ruud H

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Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells von Huseinovic, Angelina, Jaspers, Annelieke, van Splunter, Annina P, Sørgård, Hanne, Wilting, Saskia M, Swarts, Dorian R A, van der Meulen, Ida H, van Beusechem, Victor W, de Menezes, Renée X, Steenbergen, Renske D M

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Sunitinib activates Axl signaling in renal cell cancer von van der Mijn, Johannes C., Broxterman, Henk J., Knol, Jaco C., Piersma, Sander R., De Haas, Richard R., Dekker, Henk, Pham, Thang V., Van Beusechem, Victor W., Halmos, Balazs, Mier, James W., Jiménez, Connie R., Verheul, Henk M.W.

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Host gene targets for novel influenza therapies elucidated by high‐throughput RNA interference screens von Meliopoulos, Victoria A., Andersen, Lauren E., Birrer, Katherine F., Simpson, Kaylene J., Lowenthal, John W., Bean, Andrew G. D., Stambas, John, Stewart, Cameron R., Tompkins, S. Mark, Beusechem, Victor W., Fraser, Iain, Mhlanga, Musa, Barichievy, Samantha, Smith, Queta, Leake, Devin, Karpilow, Jon, Buck, Amy, Jona, Ghil, Tripp, Ralph A.

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Unleashing the Full Potential of Oncolytic Adenoviruses against Cancer by Applying RNA Interference: The Force Awakens von Brachtlova, Tereza, van Beusechem, Victor W

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Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection von Bachas, Costa, Hodzic, Jasmina, van der Mijn, Johannes C, Stoepker, Chantal, Verheul, Henk M W, Wolthuis, Rob M F, Felley-Bosco, Emanuela, van Wieringen, Wessel N, van Beusechem, Victor W, Brakenhoff, Ruud H, de Menezes, Renée X

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