EE368 Angiotensin II (ANGII) Reduces Intensive Care Unit (ICU) Length of Stay Providing Cost Savings in the Treatment of Refractory Distributive Shock (DS) von Mihalik, A, Betthauser, K, Bellomo, R

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Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring von Ashton, Nicholas J., Janelidze, Shorena, Mattsson-Carlgren, Niklas, Binette, Alexa Pichet, Strandberg, Olof, Brum, Wagner S., Karikari, Thomas K., González-Ortiz, Fernándo, Di Molfetta, Guglielmo, Meda, Francisco J., Jonaitis, Erin M., Koscik, Rebecca Langhough, Cody, Karly, Betthauser, Tobey J., Li, Yan, Vanmechelen, Eugeen, Palmqvist, Sebastian, Stomrud, Erik, Bateman, Randall J., Zetterberg, Henrik, Johnson, Sterling C., Blennow, Kaj, Hansson, Oskar

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Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers von Mattsson-Carlgren, Niklas, Salvadó, Gemma, Ashton, Nicholas J, Tideman, Pontus, Stomrud, Erik, Zetterberg, Henrik, Ossenkoppele, Rik, Betthauser, Tobey J, Cody, Karly Alex, Jonaitis, Erin M, Langhough, Rebecca, Palmqvist, Sebastian, Blennow, Kaj, Janelidze, Shorena, Johnson, Sterling C, Hansson, Oskar

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Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age von Betthauser, Tobey J, Koscik, Rebecca L, Jonaitis, Erin M, Allison, Samantha L, Cody, Karly A, Erickson, Claire M, Rowley, Howard A, Stone, Charles K, Mueller, Kimberly D, Clark, Lindsay R, Carlsson, Cynthia M, Chin, Nathaniel A, Asthana, Sanjay, Christian, Bradley T, Johnson, Sterling C

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Gut inflammation associated with age and Alzheimer’s disease pathology: a human cohort study von Heston, Margo B., Hanslik, Kendra L., Zarbock, Katie R., Harding, Sandra J., Davenport-Sis, Nancy J., Kerby, Robert L., Chin, Nathaniel, Sun, Yi, Hoeft, Ana, Deming, Yuetiva, Vogt, Nicholas M., Betthauser, Tobey J., Johnson, Sterling C., Asthana, Sanjay, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Wild, Norbert, Zetterberg, Henrik, Blennow, Kaj, Rey, Federico E., Bendlin, Barbara B., Ulland, Tyler K.

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In Vivo Comparison of Tau Radioligands 18F-THK-5351 and 18F-THK-5317 von Betthauser, Tobey J., Lao, Patrick J., Murali, Dhanabalan, Barnhart, Todd E., Furumoto, Shozo, Okamura, Nobuyuki, Stone, Charles K., Johnson, Sterling C., Christian, Bradley T.

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Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts von Betthauser, Tobey J, Bilgel, Murat, Koscik, Rebecca L, Jedynak, Bruno M, An, Yang, Kellett, Kristina A, Moghekar, Abhay, Jonaitis, Erin M, Stone, Charles K, Engelman, Corinne D, Asthana, Sanjay, Christian, Bradley T, Wong, Dean F, Albert, Marilyn, Resnick, Susan M, Johnson, Sterling C

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Human brain imaging of nicotinic acetylcholine α4β2 receptors using [18F]Nifene: Selectivity, functional activity, toxicity, aging effects, gender effects, and extrathalamic pathwa... von Mukherjee, Jogeshwar, Lao, Patrick J., Betthauser, Tobey J., Samra, Gurleen K., Pan, Min‐Liang, Patel, Ishani H., Liang, Christopher, Metherate, Raju, Christian, Bradley T.

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Crosswalk study on blood collection‐tube types for Alzheimer's disease biomarkers von Jonaitis, Erin M., Zetterberg, Henrik, Koscik, Rebecca Langhough, Betthauser, Tobey J., Van Hulle, Carol A., Hogan, Kirk, Hegge, Laura, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Gleason, Carey E., Engelman, Corinne D., Okonkwo, Ozioma C., Asthana, Sanjay, Bendlin, Barbara B., Carlsson, Cynthia M., Johnson, Sterling C., Blennow, Kaj

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Amyloid duration is associated with preclinical cognitive decline and tau PET von Koscik, Rebecca L., Betthauser, Tobey J., Jonaitis, Erin M., Allison, Samantha L., Clark, Lindsay R., Hermann, Bruce P., Cody, Karly A., Engle, Jonathan W., Barnhart, Todd E., Stone, Charles K., Chin, Nathaniel A., Carlsson, Cynthia M., Asthana, Sanjay, Christian, Bradley T., Johnson, Sterling C.

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Divergent Cortical Tau Positron Emission Tomography Patterns Among Patients With Preclinical Alzheimer Disease von Young, Christina B, Winer, Joseph R, Younes, Kyan, Cody, Karly A, Betthauser, Tobey J, Johnson, Sterling C, Schultz, Aaron, Sperling, Reisa A, Greicius, Michael D, Cobos, Inma, Poston, Kathleen L, Mormino, Elizabeth C

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Characterizing the emergence of amyloid and tau burden in Down syndrome von Zammit, Matthew D., Betthauser, Tobey J., McVea, Andrew K., Laymon, Charles M., Tudorascu, Dana L., Johnson, Sterling C., Hartley, Sigan L., Converse, Alexander K., Minhas, Davneet S., Zaman, Shahid H., Ances, Beau M., Stone, Charles K., Mathis, Chester A., Cohen, Annie D., Klunk, William E., Handen, Benjamin L., Christian, Bradley T.

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Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study von Schworer, Emily K, Zammit, Matthew D, Wang, Jiebiao, Handen, Benjamin L, Betthauser, Tobey, Laymon, Charles M, Tudorascu, Dana L, Cohen, Annie D, Zaman, Shahid H, Ances, Beau M, Mapstone, Mark, Head, Elizabeth, Christian, Bradley T, Hartley, Sigan L, Aizenstein, Howard, Ances, Beau, Andrews, Howard, Bell, Karen, Birn, Rasmus, Brickman, Adam, Bulova, Peter, Cheema, Amrita, Chen, Kewei, Christian, Bradley, Clare, Isabel, Clark, Lorraine, Cohen, Ann, Constantino, John, Doran, Eric, Fagan, Anne, Feingold, Eleanor, Foroud, Tatiana, Handen, Benjamin, Harp, Jordan, Hartley, Sigan, Head, Elizabeth, Henson, Rachel, Hom, Christy, Honig, Lawrence, Ikonomovic, Milos, Johnson, Sterling, Jordan, Courtney, Kamboh, M. Ilyas, Keator, David, Klunk, William, Kofler, Julia, Kreisl, William, Krinsky-McHale, Sharon, Lai, Florence, Lao, Patrick, Laymon, Charles, Lee, Joseph, Lott, Ira, Lupson, Victoria, Mapstone, Mark, Mathis, Chester, Minhas, Davneet, Nadkarni, Neelesh, O'Bryant, Sid, Parisi, Melissa, Pang, Deborah, Petersen, Melissa, Price, Julie, Pulsifer, Margaret, Rafii, Michael, Reiman, Eric, Rizvi, Batool, Rosas, Diana, Ryan, Laurie, Schmitt, Frederick, Schupf, Nicole, Silverman, Wayne, Tudorascu, Dana, Tumuluru, Rameshwari, Tycko, Benjamin, Varadarajan, Badri, White, Desiree, Yassa, Michael, Zaman, Shahid, Zhang, Fan

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In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand 18F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls von Betthauser, Tobey J, Cody, Karly A, Zammit, Matthew D, Murali, Dhanabalan, Converse, Alexander K, Barnhart, Todd E, Stone, Charles K, Rowley, Howard A, Johnson, Sterling C, Christian, Bradley T

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Human biodistribution and dosimetry of [18F]nifene, an α4β2 nicotinic acetylcholine receptor PET tracer von Betthauser, Tobey J., Hillmer, Ansel T., Lao, Patrick J., Ehlerding, Emily, Mukherjee, Jogeshwar, Stone, Charles K., Christian, Bradley T.

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Production of α-1,3-Galactosyltransferase Null Pigs by Means of Nuclear Transfer with Fibroblasts Bearing Loss of Heterozygosity Mutations von Kolber-Simonds, Donna, Lai, Liangxue, Watt, Steven R., Denaro, Maria, Arn, Scott, Augenstein, Monica L., Betthauser, Jeffery, Carter, David B., Greenstein, Julia L., Hao, Yanhong, Im, Gi-Sun, Liu, Zhonghua, Mell, Greg D., Murphy, Clifton N., Park, Kwang-Wook, Rieke, August, David J. J. Ryan, Sachs, David H., Forsberg, Erik J., Prather, Randall S., Hawley, Robert J., Jaenisch, Rudolf

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Lower synaptic density and higher neurofibrillary tau are associated with worse cognitive performance von DiFilippo, Alexandra H, Xin, Yangchun, Jonaitis, Erin M., Kohli, Akshay, Ennis, Gilda E., McVea, Andrew K, McLachlan, Max, Pasquesi, Mary‐Elizabeth, Davenport, Nancy J, Betthauser, Tobey J, Barnhart, Todd E, Engle, Jonathan W, Johnson, Sterling C., Bendlin, Barbara B., Christian, Bradley T

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Clinical Manifestations von Lui, Kitty K, Wang, Xinran, Stiver, Jordan, Wang, Xin, Sundermann, Erin E, Betthauser, Tobey J, Jonaitis, Erin M, Langhough, Rebecca E, Johnson, Sterling C, Banks, Sarah

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The moderating effects of sex and amyloid status on the associations between early tau burden and memory von Lui, Kitty K., Wang, Xinran, Stiver, Jordan, Wang, Xin, Sundermann, Erin E., Betthauser, Tobey J., Jonaitis, Erin M., Langhough, Rebecca E., Johnson, Sterling C., Banks, Sarah

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109 Evaluating bovine embryo developmental competence to establish pregnancy using noninvasive RNA-seq and morphological analysis von Khan, S. A., Mtango, N., Jiang, K., Betthauser, J., Plummer, S., Campbell, M., Brett, B., Ricon, G., Krisher, R. L., Rajput, S. R.

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