The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data − a case study with caffeine von Bessems, Jos G.M, Paini, Alicia, Gajewska, Monika, Worth, Andrew

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Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of si... von de Jong, Esther, Barenys, Marta, Hermsen, Sanne A.B., Verhoef, Aart, Ossendorp, Bernadette C., Bessems, Jos G.M., Piersma, Aldert H.

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Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches von Coecke, Sandra, Pelkonen, Olavi, Leite, Sofia Batista, Bernauer, Ulrike, Bessems, Jos GM, Bois, Frederic Y., Gundert-Remy, Ursula, Loizou, George, Testai, Emanuela, Zaldívar, José-Manuel

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Oral-to-inhalation route extrapolation in occupational health risk assessment: a critical assessment von Rennen, Monique A.J, Bouwman, Tialda, Wilschut, Annette, Bessems, Jos G.M, Heer, Cees De

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Proper knowledge on toxicokinetics improves human hazard testing and subsequent health risk characterisation. A case study approach von Bessems, Jos G.M., Geraets, Liesbeth

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Human risk assessment of dermal and inhalation exposures to chemicals assessed by route-to-route extrapolation: The necessity of kinetic data von Geraets, Liesbeth, Bessems, Jos G.M., Zeilmaker, Marco J., Bos, Peter M.J.

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Quantitative Extrapolation of In Vitro Whole Embryo Culture Embryotoxicity Data to Developmental Toxicity In Vivo Using the Benchmark Dose Approach von Piersma, Aldert H., Janer, Gemma, Wolterink, Gerrit, Bessems, Jos G. M., Hakkert, Betty C., Slob, Wout

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Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study von Kienhuis, Anne S., Bessems, Jos G.M., Pennings, Jeroen L.A., Driessen, Marja, Luijten, Mirjam, van Delft, Joost H.M., Peijnenburg, Ad A.C.M., der Ven, Leo T.M. van

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Subacute (28-day) toxicity of furfural in Fischer 344 rats: a comparison of the oral and inhalation route von Arts, Josje H.E., Muijser, Hans, Appel, Marko J., Frieke Kuper, C., Bessems, Jos G.M., Woutersen, Ruud A.

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The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity von van Ommen, Ben, Hendriks, Willem, Bessems, Jos G.M., Geesink, Geert, Müller, Franz, van Bladeren, Peter J.

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Evaluation of published QSARs for percutaneous penetration von Bouwman, Tialda, Bessems, Jos G.M., Cronin, Mark T.D., Van de Sandt, Han J.M.

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Neurobehavioural evaluation and kinetics of inhalation of constant or fluctuating toluene concentrations in human volunteers von Lammers, Jan H.C.M., Meuling, Wim J.A., Muijser, Hans, Freidig, Andreas P., Bessems, Jos G.M.

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Toxicological profile foro-benzyl-p-chlorophenol von Stouten, Hans, Bessems, Jos G.M.

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Toxicological profile for o-benzyl-p-chlorophenol von Stouten, Hans, Bessems, Jos G. M.

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Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes von Qiu-Ju, Li, Bessems, Jos G.M., Commandeur, Jan N.M., Adams, Bas, Vermeulen, Nico P.E.

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3,5-Disubstituted analogues of paracetamol. Synthesis, analgesic activity and cytotoxicity von Bessems, Jos G.M., Gaisser, H.-Dieter, Te Koppele, Johan M., Van Bennekom, Wouter P., Commandeur, Jan N.M., Vermeulen, Nico P.E.

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Biotransformation of 1,2-dihydronaphthalene and 1,2-dihydroanthracene by rat liver microsomes and purified cytochromes P-450. Formation of arene hydrates of naphthalene and anthrac... von Boyd, Derek R, Sharma, Narain D, Agarwal, Rajiv, McMordie, R. Austin S, Bessems, Jos G. M, van Ommen, Ben, van Bladeren, Peter J

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Paracetamol (Acetaminophen)-Induced Toxicity: Molecular and Biochemical Mechanisms, Analogues and Protective Approaches von Bessems, Jos G. M., Vermeulen, Nico P. E.

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