Mechanism of glycogen synthase inactivation and interaction with glycogenin von Marr, Laura, Biswas, Dipsikha, Daly, Leonard A., Browning, Christopher, Vial, Sarah C. M., Maskell, Daniel P., Hudson, Catherine, Bertrand, Jay A., Pollard, John, Ranson, Neil A., Khatter, Heena, Eyers, Claire E., Sakamoto, Kei, Zeqiraj, Elton

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Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels von Lolicato, Marco, Nardini, Marco, Gazzarrini, Sabrina, Möller, Stefan, Bertinetti, Daniela, Herberg, Friedrich W., Bolognesi, Martino, Martin, Holger, Fasolini, Marina, Bertrand, Jay A., Arrigoni, Cristina, Thiel, Gerhard, Moroni, Anna

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Structural basis for CARM1 inhibition by indole and pyrazole inhibitors von Sack, John S, Thieffine, Sandrine, Bandiera, Tiziano, Fasolini, Marina, Duke, Gerald J, Jayaraman, Lata, Kish, Kevin F, Klei, Herbert E, Purandare, Ashok V, Rosettani, Pamela, Troiani, Sonia, Xie, Dianlin, Bertrand, Jay A

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Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors von Bossi, Roberto T, Saccardo, M. Beatrice, Ardini, Elena, Menichincheri, Maria, Rusconi, Luisa, Magnaghi, Paola, Orsini, Paolo, Avanzi, Nilla, Borgia, Andrea Lombardi, Nesi, Marcella, Bandiera, Tiziano, Fogliatto, Gianpaolo, Bertrand, Jay A

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Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA von Swan, Michael K., Legris, Valerie, Tanner, Adam, Reaper, Philip M., Vial, Sarah, Bordas, Rebecca, Pollard, John R., Charlton, Peter A., Golec, Julian M. C., Bertrand, Jay A.

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Structural Insight into Maternal Embryonic Leucine Zipper Kinase (MELK) Conformation and Inhibition toward Structure-Based Drug Design von Canevari, Giulia, Re Depaolini, Stefania, Cucchi, Ulisse, Bertrand, Jay A, Casale, Elena, Perrera, Claudia, Forte, Barbara, Carpinelli, Patrizia, Felder, Eduard R

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Role of the Ortholog and Paralog Amino Acid Invariants in the Active Site of the UDP-MurNAc-l-alanine:d-glutamate Ligase (MurD) von Bouhss, Ahmed, Dementin, Sébastien, Parquet, Claudine, Mengin-Lecreulx, Dominique, Bertrand, Jay A, Le Beller, Dominique, Dideberg, Otto, van Heijenoort, Jean, Blanot, Didier

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First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery von Menichincheri, Maria, Bargiotti, Alberto, Berthelsen, Jens, Bertrand, Jay A, Bossi, Roberto, Ciavolella, Antonella, Cirla, Alessandra, Cristiani, Cinzia, Croci, Valter, D’Alessio, Roberto, Fasolini, Marina, Fiorentini, Francesco, Forte, Barbara, Isacchi, Antonella, Martina, Katia, Molinari, Antonio, Montagnoli, Alessia, Orsini, Paolo, Orzi, Fabrizio, Pesenti, Enrico, Pezzetta, Daniele, Pillan, Antonio, Poggesi, Italo, Roletto, Fulvia, Scolaro, Alessandra, Tatò, Marco, Tibolla, Marcellino, Valsasina, Barbara, Varasi, Mario, Volpi, Daniele, Santocanale, Corrado, Vanotti, Ermes

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Thieno[3,2- c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity von Bindi, Simona, Fancelli, Daniele, Alli, Cristina, Berta, Daniela, Bertrand, Jay A., Cameron, Alexander D., Cappella, Paolo, Carpinelli, Patrizia, Cervi, Giovanni, Croci, Valter, D’Anello, Matteo, Forte, Barbara, Laura Giorgini, M., Marsiglio, Aurelio, Moll, Juergen, Pesenti, Enrico, Pittalà, Valeria, Pulici, Maurizio, Riccardi-Sirtori, Federico, Roletto, Fulvia, Soncini, Chiara, Storici, Paola, Varasi, Mario, Volpi, Daniele, Zugnoni, Paola, Vianello, Paola

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Determination of the MurD mechanism through crystallographic analysis of enzyme complexes von Bertrand, Jay A., Auger, Geneviève, Martin, Lydie, Fanchon, Eric, Blanot, Didier, Le Beller, Dominique, van Heijenoort, Jean, Dideberg, Otto

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Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli von Bertrand, Jay A., Auger, Geneviève, Fanchon, Eric, Martin, Lydie, Blanot, Didier, van Heijenoort, Jean, Dideberg, Otto

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“Open” structures of MurD: domain movements and structural similarities with folylpolyglutamate synthetase von Bertrand, Jay A, Fanchon, Eric, Martin, Lydie, Chantalat, Laurent, Auger, Geneviève, Blanot, Didier, van Heijenoort, Jean, Dideberg, Otto

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Mechanism of Calcite Crystal Growth Inhibition by the N-terminal Undecapeptide of Lithostathine von Gerbaud, Vincent, Pignol, David, Loret, Erwann, Bertrand, Jay A., Berland, Yvon, Fontecilla-Camps, Juan-Carlos, Canselier, Jean-Paul, Gabas, Nadine, Verdier, Jean-Michel

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First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery von Menichincheri, Maria, Bargiotti, Alberto, Berthelsen, Jens, Bertrand, Jay A, Bossi, Roberto, Ciavolella, Antonella, Cirla, Alessandra, Cristiani, Cinzia, Croci, Valter, D’Alessio, Roberto, Fasolini, Marina, Fiorentini, Francesco, Forte, Barbara, Isacchi, Antonella, Martina, Katia, Molinari, Antonio, Montagnoli, Alessia, Orsini, Paolo, Orzi, Fabrizio, Pesenti, Enrico, Pezzetta, Daniele, Pillan, Antonio, Poggesi, Italo, Roletto, Fulvia, Scolaro, Alessandra, Tatò, Marco, Tibolla, Marcellino, Valsasina, Barbara, Varasi, Mario, Volpi, Daniele, Santocanale, Corrado, Vanotti, Ermes

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Water Ring Structure at DNA Interfaces: Hydration and Dynamics of DNA-Anthracycline Complexes von Lipscomb, Leigh Ann, Peek, Mary Elizabeth, Zhou, Fang Xiao, Bertrand, Jay A, VanDerveer, Donald, Williams, Loren Dean

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Oxyanion-Mediated Inhibition of Serine Proteases von Presnell, Steven R, Patil, Girish S, Mura, Cameron, Jude, Kevin M, Conley, Jennifer M, Bertrand, Jay A, Kam, Chih-Min, Powers, James C, Williams, Loren Dean

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Inhibition of Trypsin and Thrombin by Amino(4-amidinophenyl)methanephosphonate Diphenyl Ester Derivatives:  X-ray Structures and Molecular Models von Bertrand, Jay A, Oleksyszyn, Josef, Kam, Chih-Min, Boduszek, Bogdan, Presnell, Steven, Plaskon, R. Richard, Suddath, F. L, Powers, James C, Williams, Loren Dean

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DNA Distortion in bis-Intercalated Complexes von Peek, Mary Elizabeth, Lipscomb, Leigh Ann, Bertrand, Jay A, Gao, Qi, Roques, Bernard P, Garbay-Jaureguiberry, Christiane, Williams, Loren Dean

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Crystallization and preliminary crystallographic study of human lithostathine von Pignol, David, Bertrand, Jay A., Bernard, Jean‐Paul, Verdier, Jean‐Michel, Dagorn, Jean‐Charles, Fontecilla‐Camps, Juan Carlos

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Abstract C202: Targeting the mitotic checkpoint for cancer therapy with NMS-P715, a novel MPS1 kinase inhibitor von Colombo, Riccardo, Caldarelli, Marina, Mennecozzi, Milena, Giorgini, Maria L., Sola, Francesco, Cappella, Paolo, Ballinari, Dario, Perrera, Claudia, Re Depaolini, Stefania, Rusconi, Luisa, Avanzi, Nilla, Volpi, Daniele, Bossi, Roberto, Bertrand, Jay A., Pesenti, Enrico, Isacchi, Antonella, Donati, Daniele, Moll, Jurgen

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