Gemtuzumab ozogamicin for acute myeloid leukemia von Appelbaum, Frederick R., Bernstein, Irwin D.

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Ex vivo expansion of human hematopoietic stem and progenitor cells von Dahlberg, Ann, Delaney, Colleen, Bernstein, Irwin D.

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Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors von Doulatov, Sergei, Vo, Linda T., Chou, Stephanie S., Kim, Peter G., Arora, Natasha, Li, Hu, Hadland, Brandon K., Bernstein, Irwin D., Collins, James J., Zon, Leonard I., Daley, George Q.

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Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution von Bernstein, Irwin D, Delaney, Colleen, Heimfeld, Shelly, Brashem-Stein, Carolyn, Voorhies, Howard, Manger, Ronald L

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Acute myeloid leukemia stem cells and CD33-targeted immunotherapy von Walter, Roland B., Appelbaum, Frederick R., Estey, Elihu H., Bernstein, Irwin D.

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CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531 von Lamba, Jatinder K, Chauhan, Lata, Shin, Miyoung, Loken, Michael R, Pollard, Jessica A, Wang, Yi-Cheng, Ries, Rhonda E, Aplenc, Richard, Hirsch, Betsy A, Raimondi, Susana C, Walter, Roland B, Bernstein, Irwin D, Gamis, Alan S, Alonzo, Todd A, Meshinchi, Soheil

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Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo von Dignum, Tessa, Varnum-Finney, Barbara, Srivatsan, Sanjay R., Dozono, Stacey, Waltner, Olivia, Heck, Adam M., Ishida, Takashi, Nourigat-McKay, Cynthia, Jackson, Dana L., Rafii, Shahin, Trapnell, Cole, Bernstein, Irwin D., Hadland, Brandon

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NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells von Uenishi, Gene I., Jung, Ho Sun, Kumar, Akhilesh, Park, Mi Ae, Hadland, Brandon K., McLeod, Ethan, Raymond, Matthew, Moskvin, Oleg, Zimmerman, Catherine E., Theisen, Derek J., Swanson, Scott, J. Tamplin, Owen, Zon, Leonard I., Thomson, James A., Bernstein, Irwin D., Slukvin, Igor I.

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Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells von Butler, Jason M., Nolan, Daniel J., Vertes, Eva L., Varnum-Finney, Barbara, Kobayashi, Hideki, Hooper, Andrea T., Seandel, Marco, Shido, Koji, White, Ian A., Kobayashi, Mariko, Witte, Larry, May, Chad, Shawber, Carrie, Kimura, Yuki, Kitajewski, Jan, Rosenwaks, Zev, Bernstein, Irwin D., Rafii, Shahin

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Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells von Palpant, Nathan J, Pabon, Lil, Friedman, Clayton E, Roberts, Meredith, Hadland, Brandon, Zaunbrecher, Rebecca J, Bernstein, Irwin, Zheng, Ying, Murry, Charles E

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Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics von Hadland, Brandon, Varnum-Finney, Barbara, Dozono, Stacey, Dignum, Tessa, Nourigat-McKay, Cynthia, Heck, Adam M., Ishida, Takashi, Jackson, Dana L., Itkin, Tomer, Butler, Jason M., Rafii, Shahin, Trapnell, Cole, Bernstein, Irwin D.

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CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531 von Pollard, Jessica A, Loken, Michael, Gerbing, Robert B, Raimondi, Susana C, Hirsch, Betsy A, Aplenc, Richard, Bernstein, Irwin D, Gamis, Alan S, Alonzo, Todd A, Meshinchi, Soheil

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Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment von Kueh, Hao Yuan, Yui, Mary A, Ng, Kenneth K H, Pease, Shirley S, Zhang, Jingli A, Damle, Sagar S, Freedman, George, Siu, Sharmayne, Bernstein, Irwin D, Elowitz, Michael B, Rothenberg, Ellen V

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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells von Varnum-Finney, Barbara, Halasz, Lia M, Sun, Mingyi, Gridley, Thomas, Radtke, Freddy, Bernstein, Irwin D

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SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML von Kung Sutherland, May S., Walter, Roland B., Jeffrey, Scott C., Burke, Patrick J., Yu, Changpu, Kostner, Heather, Stone, Ivan, Ryan, Maureen C., Sussman, Django, Lyon, Robert P., Zeng, Weiping, Harrington, Kimberly H., Klussman, Kerry, Westendorf, Lori, Meyer, David, Bernstein, Irwin D., Senter, Peter D., Benjamin, Dennis R., Drachman, Jonathan G., McEarchern, Julie A.

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Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells von Hadland, Brandon K, Varnum-Finney, Barbara, Poulos, Michael G, Moon, Randall T, Butler, Jason M, Rafii, Shahin, Bernstein, Irwin D

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Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity von Laurenti, Elisa, Varnum-Finney, Barbara, Wilson, Anne, Ferrero, Isabel, Blanco-Bose, William E, Ehninger, Armin, Knoepfler, Paul S, Cheng, Pei-Feng, MacDonald, H Robson, Eisenman, Robert N, Bernstein, Irwin D, Trumpp, Andreas

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NOTCH1 signaling during CD4+ T-cell activation alters transcription factor networks and enhances antigen responsiveness von Wilkens, Alec B., Fulton, Elena C., Pont, Margot J., Cole, Gabriel O., Leung, Isabel, Stull, Sylvia M., Hart, Matthew R., Bernstein, Irwin D., Furlan, Scott N., Riddell, Stanley R.

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Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit von Gutman, Jonathan A., Turtle, Cameron J., Manley, Thomas J., Heimfeld, Shelly, Bernstein, Irwin D., Riddell, Stanley R., Delaney, Colleen

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CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target von Le, Quy, Hadland, Brandon, Smith, Jenny L, Leonti, Amanda, Huang, Benjamin J, Ries, Rhonda, Hylkema, Tiffany A, Castro, Sommer, Tang, Thao T, McKay, Cyd N, Perkins, LaKeisha, Pardo, Laura, Sarthy, Jay, Beckman, Amy K, Williams, Robin, Idemmili, Rhonda, Furlan, Scott, Ishida, Takashi, Call, Lindsey, Srivastava, Shivani, Loeb, Anisha M, Milano, Filippo, Imren, Suzan, Morris, Shelli M, Pakiam, Fiona, Olson, Jim M, Loken, Michael R, Brodersen, Lisa, Riddell, Stanley R, Tarlock, Katherine, Bernstein, Irwin D, Loeb, Keith R, Meshinchi, Soheil

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