DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome von Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco

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The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction von Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard, Waldmeier, Pius

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RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors von Ballard, Theresa M., Knoflach, Frédéric, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A., Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-Luc, Wettstein, Joseph G., Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W., Trube, Gerhard, Hernandez, Maria-Clemencia

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Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O‑Methyltransferase Derived from a Fragment Screening Approach Targeting the S‑Adenosyl‑l‑methionine Pocket... von Lerner, Christian, Jakob-Roetne, Roland, Buettelmann, Bernd, Ehler, Andreas, Rudolph, Markus, Rodríguez Sarmiento, Rosa María

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CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor von Lindemann, Lothar, Jaeschke, Georg, Michalon, Aubin, Vieira, Eric, Honer, Michael, Spooren, Will, Porter, Richard, Hartung, Thomas, Kolczewski, Sabine, Büttelmann, Bernd, Flament, Christophe, Diener, Catherine, Fischer, Christophe, Gatti, Silvia, Prinssen, Eric P, Parrott, Neil, Hoffmann, Gerhard, Wettstein, Joseph G

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Correction to Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O‑Methyltransferase Derived from a Fragment Screening Approach Targeting the S‑Adenosyl‑l‑methionine... von Lerner, Christian, Jakob-Roetne, Roland, Buettelmann, Bernd, Ehler, Andreas, Rudolph, Markus G, Rodríguez Sarmiento, Rosa María

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Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA α5 inverse agonists with potential for the treatment of cognitive dysfunction von BUETTELMANN, Bernd, BALLARD, Theresa M, GASSER, Rodolfo, FISCHER, Holger, HERNANDEZ, Maria-Clemencia, KNOFLACH, Frédéric, KNUST, Henner, STADLER, Heinz, THOMAS, Andrew W, TRUBE, Gerhard

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Rational design, synthesis, and structure–activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure von Ceccarelli, Simona M., Jaeschke, Georg, Buettelmann, Bernd, Huwyler, Jörg, Kolczewski, Sabine, Peters, Jens-Uwe, Prinssen, Eric, Porter, Richard, Spooren, Will, Vieira, Eric

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Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABA sub(A) alpha 5 inverse agonists with potential for the treatment of cognitive dysfunct... von Buettelmann, Bernd, Ballard, Theresa M, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frederic, Knust, Henner, Stadler, Heinz, Thomas, Andrew W, Trube, Gerhard

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The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABA sub(A) alpha 5 inverse agonists for the treatment of cognitive dysfunction von Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frederic, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W, Trube, Gerhard, Waldmeier, Pius

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Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists von Jaeschke, Georg, Porter, Richard, Büttelmann, Bernd, Ceccarelli, Simona M., Guba, Wolfgang, Kuhn, Bernd, Kolczewski, Sabine, Huwyler, Jörg, Mutel, Vincent, Peters, Jens-Uwe, Ballard, Theresa, Prinssen, Eric, Vieira, Eric, Wichmann, Jürgen, Spooren, Will

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The discovery and unique pharmacological profile of RO4938581 and R04882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction von KNUST, Henner, ACHERMANN, Guido, THOMAS, Andrew W, TRUBE, Gerhard, WALDMEIER, Pius, BALLARD, Theresa, BUETTELMANN, Bernd, GASSER, Rodolfo, FISCHER, Holger, HERNANDEZ, Maria-Clemencia, KNOFLACH, Frédéric, KOBLET, Andreas, STADLER, Heinz

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The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABA A α5 inverse agonists for the treatment of cognitive dysfunction von Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard, Waldmeier, Pius

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Imidazo[1,5- a][1,2,4]-triazolo[1,5- d][1,4]benzodiazepines as potent and highly selective GABA A α5 inverse agonists with potential for the treatment of cognitive dysfunction von Buettelmann, Bernd, Ballard, Theresa M., Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Knust, Henner, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard

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RO4938581, a novel cognitive enhancer acting at GABAA [alpha]5 subunit-containing receptors von Ballard, Theresa M, Knoflach, Frédéric, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A, Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-luc, Wettstein, Joseph G, Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W, Trube, Gerhard, Hernandez, Maria-clemencia

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RO4938581, a novel cognitive enhancer acting at GABAA a5 subunit-containing receptors von Ballard, Theresa M, Knoflach, FrEdEric, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A, Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-Luc, Wettstein, Joseph G, Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W, Trube, Gerhard, Hernandez, Maria-Clemencia

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R04938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors: Special Issue on Cognitive Enhancers von BALLARD, Theresa M, KNOFLACH, Frédéric, KNUST, Henner, THOMAS, Andrew W, TRUBE, Gerhard, HERNANDEZ, Maria-Clemencia, PRINSSEN, Eric, BORRONI, Edilio, VIVIAN, Jeffrey A, BASILE, Jennifer, GASSER, Rodolfo, MOREAU, Jean-Luc, WETTSTEIN, Joseph G, BUETTELMANN, Bernd

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RO4938581, a novel cognitive enhancer acting at GABAA α5 subunit-containing receptors von Ballard, Theresa M., Knoflach, Frédéric, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A., Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-Luc, Wettstein, Joseph G., Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W., Trube, Gerhard, Hernandez, Maria-Clemencia

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RO4938581, a novel cognitive enhancer acting at GABA sub(A) a5 subunit-containing receptors von Ballard, Theresa M, Knoflach, Frederic, Prinssen, Eric, Borroni, Edilio, Vivian, Jeffrey A, Basile, Jennifer, Gasser, Rodolfo, Moreau, Jean-Luc, Wettstein, Joseph G, Buettelmann, Bernd, Knust, Henner, Thomas, Andrew W, Trube, Gerhard, Hernandez, Maria-Clemencia

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Metabolite Identification via LC-SPE-NMR-MS of the In vitro Biooxidation Products of a Lead mGlu5 Allosteric Antagonist and Impact on the Improvement of Metabolic Stability in the... von Ceccarelli, Simona M., Schlotterbeck, Götz, Boissin, Patrick, Binder, Martin, Buettelmann, Bernd, Hanlon, Steven, Jaeschke, Georg, Kolczewski, Sabine, Kupfer, Ernst, Peters, Jens-Uwe, Porter, Richard H. P., Prinssen, Eric P., Rueher, Marianne, Ruf, Iris, Spooren, Will, Stämpfli, Andreas, Vieira, Eric

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