Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma von Berko, Esther R., Witek, Gabriela M., Matkar, Smita, Petrova, Zaritza O., Wu, Megan A., Smith, Courtney M., Daniels, Alex, Kalna, Joshua, Kennedy, Annie, Gostuski, Ivan, Casey, Colleen, Krytska, Kateryna, Gerelus, Mark, Pavlick, Dean, Ghazarian, Susan, Park, Julie R., Marachelian, Araz, Maris, John M., Goldsmith, Kelly C., Radhakrishnan, Ravi, Lemmon, Mark A., Mossé, Yaël P.

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Thrown for a Loop: Awakening BORIS to Evade ALK Inhibition Therapy von Berko, Esther R., Mossé, Yael P.

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Lorlatinib with or without chemotherapy in ALK-driven refractory/relapsed neuroblastoma: phase 1 trial results von Goldsmith, Kelly C., Park, Julie R., Kayser, Kimberly, Malvar, Jemily, Chi, Yueh-Yun, Groshen, Susan G., Villablanca, Judith G., Krytska, Kateryna, Lai, Lillian M., Acharya, Patricia T., Goodarzian, Fariba, Pawel, Bruce, Shimada, Hiroyuki, Ghazarian, Susan, States, Lisa, Marshall, Lynley, Chesler, Louis, Granger, Meaghan, Desai, Ami V., Mody, Rajen, Morgenstern, Daniel A., Shusterman, Suzanne, Macy, Margaret E., Pinto, Navin, Schleiermacher, Gudrun, Vo, Kieuhoa, Thurm, Holger C., Chen, Joseph, Liyanage, Marlon, Peltz, Gerson, Matthay, Katherine K., Berko, Esther R., Maris, John M., Marachelian, Araz, Mossé, Yael P.

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Unusual Characteristics of the DNA Binding Domain of Epigenetic Regulatory Protein MeCP2 Determine Its Binding Specificity von Khrapunov, Sergei, Warren, Christopher, Cheng, Huiyong, Berko, Esther R, Greally, John M, Brenowitz, Michael

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Serial Profiling of Circulating Tumor DNA Identifies Dynamic Evolution of Clinically Actionable Genomic Alterations in High-Risk Neuroblastoma von Bosse, Kristopher R, Giudice, Anna Maria, Lane, Maria V, McIntyre, Brendan, Schürch, Patrick M, Pascual-Pasto, Guillem, Buongervino, Samantha N, Suresh, Sriyaa, Fitzsimmons, Alana, Hyman, Adam, Gemino-Borromeo, Maria, Saggio, Jennifer, Berko, Esther R, Daniels, Alexander A, Stundon, Jennifer, Friedrichsen, Megan, Liu, Xin, Margolis, Matthew L, Li, Marilyn M, Tierno, Marni Brisson, Oxnard, Geoffrey R, Maris, John M, Mossé, Yael P

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Detecting, quantifying, and discriminating the mechanism of mosaic chromosomal aneuploidies using MAD-seq von Kong, Yu, Berko, Esther R, Marcketta, Anthony, Maqbool, Shahina B, Simões-Pires, Claudia A, Kronn, David F, Ye, Kenny Q, Suzuki, Masako, Auton, Adam, Greally, John M

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How might epigenetic dysregulation in early embryonic life contribute to autism spectrum disorder? von Berko, Esther R, Greally, John M

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Mosaic epigenetic dysregulation of ectodermal cells in autism spectrum disorder von Berko, Esther R, Suzuki, Masako, Beren, Faygel, Lemetre, Christophe, Alaimo, Christine M, Calder, R Brent, Ballaban-Gil, Karen, Gounder, Batya, Kampf, Kaylee, Kirschen, Jill, Maqbool, Shahina B, Momin, Zeineen, Reynolds, David M, Russo, Natalie, Shulman, Lisa, Stasiek, Edyta, Tozour, Jessica, Valicenti-McDermott, Maria, Wang, Shenglong, Abrahams, Brett S, Hargitai, Joseph, Inbar, Dov, Zhang, Zhengdong, Buxbaum, Joseph D, Molholm, Sophie, Foxe, John J, Marion, Robert W, Auton, Adam, Greally, John M

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Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma von Krytska, Kateryna, Casey, Colleen E, Pogoriler, Jennifer, Martinez, Daniel, Rathi, Komal S, Farrel, Alvin, Berko, Esther R, Tsang, Matthew, Sano, Renata R, Kendsersky, Nathan, Erickson, Stephen W, Teicher, Beverly A, Isse, Kumiko, Saunders, Laura, Smith, Malcolm A, Maris, John M, Mossé, Yael P

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4558 Investigating the functional consequences of anaplastic lymphoma kinase (ALK) mutations arising upon Lorlatinib treatment von Witek, Gabriela Maria, Miller, Whelton, Slochower, David, Berko, Esther, Mossé, Yael, Lemmon, Mark, Radhakrishnan, Ravi

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Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design von Rokita, Jo Lynne, Rathi, Komal S., Cardenas, Maria F., Upton, Kristen A., Jayaseelan, Joy, Cross, Katherine L., Pfeil, Jacob, Egolf, Laura E., Way, Gregory P., Farrel, Alvin, Kendsersky, Nathan M., Patel, Khushbu, Gaonkar, Krutika S., Modi, Apexa, Berko, Esther R., Lopez, Gonzalo, Vaksman, Zalman, Mayoh, Chelsea, Nance, Jonas, McCoy, Kristyn, Haber, Michelle, Evans, Kathryn, McCalmont, Hannah, Bendak, Katerina, Böhm, Julia W., Marshall, Glenn M., Tyrrell, Vanessa, Kalletla, Karthik, Braun, Frank K., Qi, Lin, Du, Yunchen, Zhang, Huiyuan, Lindsay, Holly B., Zhao, Sibo, Shu, Jack, Baxter, Patricia, Morton, Christopher, Kurmashev, Dias, Zheng, Siyuan, Chen, Yidong, Bowen, Jay, Bryan, Anthony C., Leraas, Kristen M., Coppens, Sara E., Doddapaneni, HarshaVardhan, Momin, Zeineen, Zhang, Wendong, Sacks, Gregory I., Hart, Lori S., Krytska, Kateryna, Mosse, Yael P., Gatto, Gregory J., Sanchez, Yolanda, Greene, Casey S., Diskin, Sharon J., Vaske, Olena Morozova, Haussler, David, Gastier-Foster, Julie M., Kolb, E. Anders, Gorlick, Richard, Li, Xiao-Nan, Reynolds, C. Patrick, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A., Lock, Richard B., Raman, Pichai, Wheeler, David A., Maris, John M.

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Phase I trial of lorlatinib in combination with topotecan/cyclophosphamide in children with ALK-driven refractory or relapsed neuroblastoma: A new approaches to neuroblastoma thera... von Goldsmith, Kelly C., Mosse, Yael P., Kayser, Kimberly, Chi, Yueh-Yun, Chioda, Marc, Thurm, Holger C., Chen, Joseph, Krishnaswami, Sriram, Peltz, Gerson, Granger, Meaghan, Mody, Rajen, Marshall, Lynley V., Desai, Ami Vijay, Berko, Esther, Maris, John M., Matthay, Katherine K., Ghazarian, Suzy, Park, Julie R., Marachelian, Araz

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Reducing Dependence on General Anesthesia for Pediatric Oncology Outpatients Undergoing Repeated Lumbar Punctures von Berko, Esther R., Wei, Yahui, Stiglich, Emily, Klingman, Derek, Vardaro, Julie, Tasian, Sarah K, McDonough, Sara, Oranges, Katelyn, Meyers, Kelly, Aber, Eileen, Kolb, Miriam, Borel, Lindsay, Evageliou, Nicholas, Citrin, Rebecca, Minturn, Jane, Reilly, Anne, Rheingold, Susan R.

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Phase I trial of lorlatinib in patients with ALK-driven refractory or relapsed neuroblastoma: A New Approaches to Neuroblastoma Consortium study von Goldsmith, Kelly C., Kayser, Kimberly, Groshen, Susan G., Chioda, Marc, Thurm, Holger C., Chen, Joseph, Peltz, Gerson, Granger, Meaghan, Maris, John, Matthay, Katherine K., Ghazarian, Suzy, Park, Julie R., Berko, Esther, Marachelian, Araz, Mosse, Yael P.

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Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder: e1004402 von Berko, Esther R, Suzuki, Masako, Beren, Faygel, Lemetre, Christophe, Alaimo, Christine M, Calder, R Brent, Ballaban-Gil, Karen, Gounder, Batya, Kampf, Kaylee, Kirschen, Jill, Maqbool, Shahina B, Momin, Zeineen, Reynolds, David M, Russo, Natalie, Shulman, Lisa, Stasiek, Edyta, Tozour, Jessica, Valicenti-McDermott, Maria, Wang, Shenglong, Abrahams, Brett S, Hargitai, Joseph, Inbar, Dov, Zhang, Zhengdong, Buxbaum, Joseph D, Molholm, Sophie, Foxe, John J, Marion, Robert W, Auton, Adam, Greally, John M

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Epigenetic studies in autism spectrum disorder von Greally, John, Berko, Esther

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Epigenetic studies in autism spectrum disorder von Greally, John, Berko, Esther

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Epigenetic studies in autism spectrum disorder von Greally, John, Berko, Esther

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Epigenetic studies in autism spectrum disorder von Greally, John, Berko, Esther

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Membrane-Anchored β2-Microglobulin Stabilizes a Highly Receptive State of MHC Class I Molecules von Berko, Dikla, Carmi, Yaron, Cafri, Gal, Ben-Zaken, Shimrit, Sheikhet, Helena Migalovich, Tzehoval, Esther, Eisenbach, Lea, Margalit, Alon, Gross, Gideon

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