Gastrointestinal hormonal responses on GPR119 activation in lean and diseased rodent models of type 2 diabetes von Patel, S, Mace, O J, Tough, I R, White, J, Cock, T-A, Warpman Berglund, U, Schindler, M, Cox, H M

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Validation and development of MTH1 inhibitors for treatment of cancer von Warpman Berglund, U., Sanjiv, K., Gad, H., Kalderén, C., Koolmeister, T., Pham, T., Gokturk, C., Jafari, R., Maddalo, G., Seashore-Ludlow, B., Chernobrovkin, A., Manoilov, A., Pateras, I.S., Rasti, A., Jemth, A.-S., Almlöf, I., Loseva, O., Visnes, T., Einarsdottir, B.O., Gaugaz, F.Z., Saleh, A., Platzack, B., Wallner, O.A., Vallin, K.S.A., Henriksson, M., Wakchaure, P., Borhade, S., Herr, P., Kallberg, Y., Baranczewski, P., Homan, E.J., Wiita, E., Nagpal, V., Meijer, T., Schipper, N., Rudd, S.G., Bräutigam, L., Lindqvist, A., Filppula, A., Lee, T.-C., Artursson, P., Nilsson, J.A., Gorgoulis, V.G., Lehtiö, J., Zubarev, R.A., Scobie, M., Helleday, T.

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365: The interplay between the redox environment, MTH1 and cancer von Braeutigam, L, Fiskesund, R, Warpman-Berglund, U, Helleday, T

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835: Inhibiting MTH1 kills cancer cells by preventing sanitisation of oxidised dNTP pool von Warpman Berglund, U, Gad, H, Jemth, A.S, Koolmeister, T, Gokturk, C, Pham, T, Nilsson, J, Eshtad, S, Scobie, M, Helleday, T

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Coexpression of MTH1 and PMS2 Is Associated with Advanced Disease and Disease Progression after Therapy in Melanoma von Das, Ishani, Tuominen, Rainer, Helleday, Thomas, Hansson, Johan, Warpman Berglund, Ulrika, Egyházi Brage, Suzanne

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A phenomics approach for antiviral drug discovery von Rietdijk, Jonne, Tampere, Marianna, Pettke, Aleksandra, Georgiev, Polina, Lapins, Maris, Warpman-Berglund, Ulrika, Spjuth, Ola, Puumalainen, Marjo-Riitta, Carreras-Puigvert, Jordi

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Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids von Pettke, Aleksandra, Tampere, Marianna, Pronk, Robin, Wallner, Olov, Falk, Anna, Warpman Berglund, Ulrika, Helleday, Thomas, Mirazimi, Ali, Puumalainen, Marjo-Riitta

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Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies von Herold, Nikolas, Rudd, Sean G, Ljungblad, Linda, Sanjiv, Kumar, Myrberg, Ida Hed, Paulin, Cynthia B J, Heshmati, Yaser, Hagenkort, Anna, Kutzner, Juliane, Page, Brent D G, Calderón-Montaño, José M, Loseva, Olga, Jemth, Ann-Sofie, Bulli, Lorenzo, Axelsson, Hanna, Tesi, Bianca, Valerie, Nicholas C K, Höglund, Andreas, Bladh, Julia, Wiita, Elisée, Sundin, Mikael, Uhlin, Michael, Rassidakis, Georgios, Heyman, Mats, Tamm, Katja Pokrovskaja, Warpman-Berglund, Ulrika, Walfridsson, Julian, Lehmann, Sören, Grandér, Dan, Lundbäck, Thomas, Kogner, Per, Henter, Jan-Inge, Helleday, Thomas, Schaller, Torsten

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Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy von Rudd, Sean G, Tsesmetzis, Nikolaos, Sanjiv, Kumar, Paulin, Cynthia BJ, Sandhow, Lakshmi, Kutzner, Juliane, Hed Myrberg, Ida, Bunten, Sarah S, Axelsson, Hanna, Zhang, Si Min, Rasti, Azita, Mäkelä, Petri, Coggins, Si'Ana A, Tao, Sijia, Suman, Sharda, Branca, Rui M, Mermelekas, Georgios, Wiita, Elisée, Lee, Sun, Walfridsson, Julian, Schinazi, Raymond F, Kim, Baek, Lehtiö, Janne, Rassidakis, Georgios Z, Pokrovskaja Tamm, Katja, Warpman‐Berglund, Ulrika, Heyman, Mats, Grandér, Dan, Lehmann, Sören, Lundbäck, Thomas, Qian, Hong, Henter, Jan‐Inge, Schaller, Torsten, Helleday, Thomas, Herold, Nikolas

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Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis von Mur, Pilar, Jemth, Ann‐Sofie, Bevc, Luka, Amaral, Nuno, Navarro, Matilde, Valdés‐Mas, Rafael, Pons, Tirso, Aiza, Gemma, Urioste, Miguel, Valencia, Alfonso, Lázaro, Conxi, Moreno, Victor, Puente, Xose S., Stenmark, Pål, Warpman‐Berglund, Ulrika, Capellá, Gabriel, Helleday, Thomas, Valle, Laura

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Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses von Tampere, Marianna, Pettke, Aleksandra, Salata, Cristiano, Wallner, Olov, Koolmeister, Tobias, Cazares-Korner, Armando, Visnes, Torkild, Hesselman, Maria Carmen, Kunold, Elena, Wiita, Elisee, Kalderen, Christina, Lightowler, Molly, Jemth, Ann-Sofie, Lehtio, Janne, Rosenquist, Asa, Warpman-Berglund, Ulrika, Helleday, Thomas, Mirazimi, Ali, Jafari, Rozbeh, Puumalainen, Marjo-Riitta

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552 - Ex vivo culture of circulating tumour cell derived explants to facilitate rapid therapy testing in small cell lung cancer von Lallo, A., Berglund, U. Warpman, Frese, K., Potter, D., Helleday, T., Dive, C.

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Development and validation of method for TH588 and TH287, potent MTH1 inhibitors and new anti-cancer agents, for pharmacokinetic studies in mice plasma von Saleh, Aljona, Gökturk, Camilla, Warpman-Berglund, Ulrika, Helleday, Thomas, Granelli, Ingrid

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Ex vivo culture of circulating tumour cell derived explants to facilitate rapid therapy testing in small cell lung cancer von Lallo, A, Berglund, U. Warpman, Frese, K, Potter, D, Helleday, T, Dive, C

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The interplay between the redox environment, MTH1 and cancer von Braeutigam, L, Fiskesund, R, Warpman-Berglund, U, Helleday, T

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Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway von Shen, J, Guillén Mancina, E, Chen, S, Manolakou, T, Gad, H, Warpman Berglund, U, Sanjiv, K, Helleday, T

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Coexpression of MTH1 and PMS2 is associated with advanced disease and disease progression after therapy in melanoma von Das, I, Tuominen, R, Helleday, T, Hansson, J, Warpman Berglund, U, Egyházi Brage, S

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The one‐carbon metabolic enzyme MTHFD2 promotes resection and homologous recombination after ionizing radiation von Marttila, P, Bonagas, N, Chalkiadaki, C, Stigsdotter, H, Schelzig, K, Shen, J, Farhat, C.M, Hondema, A, Albers, J, Wiita, E, Rasti, A, Warpman Berglund, U, Slipicevic, A, Mortusewicz, O, Helleday, T

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Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming von Pateras, I.S, Williams, C, Gianniou, D.D, Margetis, A.T, Avgeris, M, Rousakis, P, Legaki, A.-I, Mirtschink, P, Zhang, W, Panoutsopoulou, K, Delis, A.D, Pagakis, S.N, Tang, W, Ambs, S, Warpman Berglund, U, Helleday, T, Varvarigou, A, Chatzigeorgiou, A, Nordström, A, Tsitsilonis, O.E, Trougakos, I.P, Gilthorpe, J.D, Frisan, T

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In silico druggability assessment of the NUDIX hydrolase protein family as a workflow for target prioritization von Michel, M, Homan, E.J, Wiita, E, Pedersen, K, Almlöf, I, Gustavsson, A-L, Lundbäck, T, Helleday, T, Warpman Berglund, U

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