Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach von El-Mesallamy, Hala O, El Magdoub, Hekmat M, Chapman, James M, Hamdy, Nadia M, Schaalan, Mona F, Hammad, Lamiaa N, Berger, Sondra H

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Thymidylate synthase as a chemotherapeutic drug target: Where are we after fifty years? von Berger, Franklin G., Berger, Sondra H.

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Uracil in DNA: Consequences for carcinogenesis and chemotherapy von Berger, Sondra H., Pittman, Douglas L., Wyatt, Michael D.

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Involvement of base excision repair in response to therapy targeted at thymidylate synthase von Li, Li, Berger, Sondra H, Wyatt, Michael D

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Evolution of Metamorphism in Thymidylate Synthases Within the Primate Lineages von Luo, BeiBei, Johnson, Saphronia R., Lebioda, Lukasz, Berger, Sondra H.

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Human thymidylate synthase with loop 181–197 stabilized in an inactive conformation: Ligand interactions, phosphorylation, and inhibition profiles von Luo, BeiBei, Repalli, Jayanthi, Yousef, Al‐Motassem, Johnson, Saphronia R., Lebioda, Lukasz, Berger, Sondra H.

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Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability von Huang, Xiao, Gibson, Lydia M, Bell, Brittnaie J, Lovelace, Leslie L, Peña, Maria Marjorette O, Berger, Franklin G, Berger, Sondra H, Lebioda, Lukasz

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Human Thymidylate Synthase Is in the Closed Conformation When Complexed with dUMP and Raltitrexed, an Antifolate Drug von Phan, Jason, Koli, Sangita, Minor, Wladek, Dunlap, R. Bruce, Berger, Sondra H, Lebioda, Lukasz

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Variants of human thymidylate synthase with loop 181–197 stabilized in the inactive conformation von Lovelace, Leslie L., Johnson, Saphronia R., Gibson, Lydia M., Bell, Brittnaie J., Berger, Sondra H., Lebioda, Lukasz

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Effects of ligand binding and conformational switching on intracellular stability of human thymidylate synthase von Berger, Sondra H., Berger, Franklin G., Lebioda, Lukasz

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Developmental abnormalities in multiple proliferative tissues of ApcMin/+ mice von You, Shaojin, Ohmori, Masami, Peña, Maria Marjorette O., Nassri, Basel, Quiton, Jovelyn, Al-Assad, Ziad A., Liu, Lucy, Wood, Patricia A., Berger, Sondra H., Liu, ZhiJian, Wyatt, Michael D., Price, Robert L., Berger, Franklin G., Hrushesky, William J. M.

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Structure of Human Thymidylate Synthase Suggests Advantages of Chemotherapy with Noncompetitive Inhibitors von Phan, J, Steadman, D J, Koli, S, Ding, W C, Minor, W, Dunlap, R B, Berger, S H, Lebioda, L

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Determination of apoptosis, uracil incorporation, DNA strand breaks, and sister chromatid exchanges under conditions of thymidylate deprivation in a model of BER deficiency von Li, Li, Connor, Ellen E., Berger, Sondra H., Wyatt, Michael D.

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Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice von You, Shaojin, Ohmori, Masami, Peña, Maria Marjorette O, Nassri, Basel, Quiton, Jovelyn, Al-Assad, Ziad A, Liu, Lucy, Wood, Patricia A, Berger, Sondra H, Liu, Zhijian, Wyatt, Michael D, Price, Robert L, Berger, Franklin G, Hrushesky, William J M

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Abstract 2670: CONFORMATIONAL PLASTICITY OF HUMAN THYMIDYLATE SYNTHASE von LUO, BEIBEI, Berger, Sondra H.

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Abstract 1348: The discovery of novel inhibitors that downregulate human thymidylate synthase von Repalli, Jayanthi, Chapman, James, McInnes, Campbell, Berger, Sondra H.

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Abstract 5508: Screening Of Novel Thymidylate Synthase Inhibitors von Repalli, Jayanthi, Robinson, Matthew R., Gumina, Giuseppe, Berger, Sondra H.

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Isolation and characterization of a thymidylate synthase-deficient human colon tumor cell line von Hoganson, Diana K, Williams, Angela W, Berger, Sondra H

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A Hydroxyl Group at Residue 216 Is Essential for Catalysis by Human Thymidylate Synthase von Williams, Angela W, Dunlap, R. Bruce, Berger, Sondra H

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A Structural Role for Glutamine 214 in Human Thymidylate Synthase von Steadman, David J, Zhao, Pei-Shan, Spencer, H. Trent, Dunlap, R. Bruce, Berger, Sondra H

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