The emerging importance of predictive ADME simulation in drug discovery von Selick, Harold E, Beresford, Alan P, Tarbit, Michael H

Volltext

ADME/PK as part of a rational approach to drug discovery von Eddershaw, Peter J, Beresford, Alan P, Bayliss, Martin K

Volltext

Focus on success: using a probabilistic approach to achieve an optimal balance of compound properties in drug discovery von Segall, Matt D, Beresford, Alan P, Gola, Joelle MR, Hawksley, Dan, Tarbit, Mike H

Volltext

Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102 von Lewis, David F.V., Lake, Brian G., George, Stephen G., Dickins, Maurice, Eddershaw, Peter J., Tarbit, Michael H., Beresford, Alan P., Goldfarb, Peter S., Guengerich, F.Peter

Volltext

CYP1A1: Friend or Foe? von Beresford, Alan P.

Volltext

Compound prioritization for drug discovery von KENNETH R. KORZEKWA, ALAN P. BERESFORD

Volltext bestellen

COMPOUND PRIORITIZATION FOR DRUG DISCOVERY von BERESFORD, ALAN, P, KORZEKWA, KENNETH, R

Volltext bestellen

COMPOUND PRIORITIZATION FOR DRUG DISCOVERY von BERESFORD, ALAN, P, EWING, TODD, J., A, KORZEKWA, KENNETH, R, GALLION, STEVEN, LEE

Volltext bestellen

Biodiversity of the Bacterial Flora on the Surface of a Smear Cheese von BRENNAN, Noelle M, WARD, Alan C, BERESFORD, Thomas P, FOX, Patrick F, GOODFELLOW, Michael, COGAN, Timothy M

Volltext

Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors von Estrada, Anthony A, Liu, Xingrong, Baker-Glenn, Charles, Beresford, Alan, Burdick, Daniel J, Chambers, Mark, Chan, Bryan K, Chen, Huifen, Ding, Xiao, DiPasquale, Antonio G, Dominguez, Sara L, Dotson, Jennafer, Drummond, Jason, Flagella, Michael, Flynn, Sean, Fuji, Reina, Gill, Andrew, Gunzner-Toste, Janet, Harris, Seth F, Heffron, Timothy P, Kleinheinz, Tracy, Lee, Donna W, Le Pichon, Claire E, Lyssikatos, Joseph P, Medhurst, Andrew D, Moffat, John G, Mukund, Susmith, Nash, Kevin, Scearce-Levie, Kimberly, Sheng, Zejuan, Shore, Daniel G, Tran, Thuy, Trivedi, Naimisha, Wang, Shumei, Zhang, Shuo, Zhang, Xiaolin, Zhao, Guiling, Zhu, Haitao, Sweeney, Zachary K

Volltext

Use of Hydrostatic Pressure for Inactivation of Microbial Contaminants in Cheese von O'Reilly, C E, O'Connor, P M, Kelly, A L, Beresford, T P, Murphy, P M

Volltext

TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets von Yeung, David T., Osborn, Michael P., White, Deborah L., Branford, Susan, Braley, Jodi, Herschtal, Alan, Kornhauser, Michael, Issa, Samar, Hiwase, Devendra K., Hertzberg, Mark, Schwarer, Anthony P., Filshie, Robin, Arthur, Christopher K., Kwan, Yiu Lam, Trotman, Judith, Forsyth, Cecily J., Taper, John, Ross, David M., Beresford, Jennifer, Tam, Constantine, Mills, Anthony K., Grigg, Andrew P., Hughes, Timothy P.

Volltext

Effect of milk pasteurization temperature and in situ whey protein denaturation on the composition, texture and heat-induced functionality of half-fat Cheddar cheese von Rynne, Nuala M., Beresford, Thomas P., Kelly, Alan.L., Guinee, Timothy P.

Volltext

Archaeogenomic evidence of punctuated genome evolution in Gossypium von Palmer, Sarah A, Clapham, Alan J, Rose, Pamela, Freitas, Fábio O, Owen, Bruce D, Beresford-Jones, David, Moore, Jonathan D, Kitchen, James L, Allaby, Robin G

Volltext

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relat... von Smith, Paul W, Sollis, Steven L, Howes, Peter D, Cherry, Peter C, Starkey, Ian D, Cobley, Kevin N, Weston, Helen, Scicinski, Jan, Merritt, Andrew, Whittington, Andrew, Wyatt, Paul, Taylor, Neil, Green, Darren, Bethell, Richard, Madar, Safia, Fenton, Robert J, Morley, Peter J, Pateman, Tony, Beresford, Alan

Volltext

Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors von Estrada, Anthony A, Chan, Bryan K, Baker-Glenn, Charles, Beresford, Alan, Burdick, Daniel J, Chambers, Mark, Chen, Huifen, Dominguez, Sara L, Dotson, Jennafer, Drummond, Jason, Flagella, Michael, Fuji, Reina, Gill, Andrew, Halladay, Jason, Harris, Seth F, Heffron, Timothy P, Kleinheinz, Tracy, Lee, Donna W, Pichon, Claire E. Le, Liu, Xingrong, Lyssikatos, Joseph P, Medhurst, Andrew D, Moffat, John G, Nash, Kevin, Scearce-Levie, Kimberly, Sheng, Zejuan, Shore, Daniel G, Wong, Susan, Zhang, Shuo, Zhang, Xiaolin, Zhu, Haitao, Sweeney, Zachary K

Volltext

High pressure treatment: applications in cheese manufacture and ripening von O'Reilly, Ciara E, Kelly, Alan L, Murphy, Patrick M, Beresford, Thomas P

Volltext

Effect of milk pasteurisation temperature on age-related changes in lactose metabolism, pH and the growth of non-starter lactic acid bacteria in half-fat Cheddar cheese von Rynne, Nuala M., Beresford, Thomas P., Kelly, Alan L., Guinee, Timothy P.

Volltext

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals von Guo, Yiran, Lanktree, Matthew B, Taylor, Kira C, Hakonarson, Hakon, Lange, Leslie A, Keating, Brendan J

Volltext

Effect of high-pressure treatment of 1 day-old full-fat Cheddar cheese on subsequent quality and ripening von Rynne, Nuala M., Beresford, Thomas P., Guinee, Timothy P., Sheehan, Elizabeth, Delahunty, Conor M., Kelly, Alan L.

Volltext