Acquired PTPN11 mutations occur rarely in adult patients with myelodysplastic syndromes and chronic myelomonocytic leukemia von Loh, Mignon L., Martinelli, Simone, Cordeddu, Viviana, Reynolds, Melissa G., Vattikuti, Shashaank, Lee, Connie M., Wulfert, Michael, Germing, Ulrich, Haas, Peter, Niemeyer, Charlotte, Beran, Miloslav E., Strom, Sara, Lübbert, Michael, Sorcini, Mariella, Estey, Elihu H., Gattermann, Norbert, Tartaglia, Marco

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Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation von Moran-Crusio, Kelly, Reavie, Linsey, Shih, Alan, Abdel-Wahab, Omar, Ndiaye-Lobry, Delphine, Lobry, Camille, Figueroa, Maria E., Vasanthakumar, Aparna, Patel, Jay, Zhao, Xinyang, Perna, Fabiana, Pandey, Suveg, Madzo, Jozef, Song, Chunxiao, Dai, Qing, He, Chuan, Ibrahim, Sherif, Beran, Miloslav, Zavadil, Jiri, Nimer, Stephen D., Melnick, Ari, Godley, Lucy A., Aifantis, Iannis, Levine, Ross L.

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Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies von Abdel-Wahab, Omar, Mullally, Ann, Hedvat, Cyrus, Garcia-Manero, Guillermo, Patel, Jay, Wadleigh, Martha, Malinge, Sebastien, Yao, JinJuan, Kilpivaara, Outi, Bhat, Rukhmi, Huberman, Kety, Thomas, Sabrena, Dolgalev, Igor, Heguy, Adriana, Paietta, Elisabeth, Le Beau, Michelle M., Beran, Miloslav, Tallman, Martin S., Ebert, Benjamin L., Kantarjian, Hagop M., Stone, Richard M., Gilliland, D. Gary, Crispino, John D., Levine, Ross L.

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Long‐term follow‐up results of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper‐CVAD), a dose‐intensive regimen, in adult acute lymphocytic le... von Kantarjian, Hagop, Thomas, Deborah, O'Brien, Susan, Cortes, Jorge, Giles, Francis, Jeha, Sima, Bueso‐Ramos, Carlos E., Pierce, Sherry, Shan, Jianqin, Koller, Charles, Beran, Miloslav, Keating, Michael, Freireich, Emil J.

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FLT3 Mutations Confer Enhanced Proliferation and Survival Properties to Multipotent Progenitors in a Murine Model of Chronic Myelomonocytic Leukemia von Lee, Benjamin H., Tothova, Zuzana, Levine, Ross L., Anderson, Kristina, Buza-Vidas, Natalija, Cullen, Dana E., McDowell, Elizabeth P., Adelsperger, Jennifer, Fröhling, Stefan, Huntly, Brian J.P., Beran, Miloslav, Jacobsen, Sten Eirik, Gilliland, D. Gary

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JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome–negative CML, and megakaryocytic leukemia von Jelinek, Jaroslav, Oki, Yasuhiro, Gharibyan, Vazganush, Bueso-Ramos, Carlos, Prchal, Josef T., Verstovsek, Srdan, Beran, Miloslav, Estey, Elihu, Kantarjian, Hagop M., Issa, Jean-Pierre J.

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Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia von Cheson, Bruce D., Greenberg, Peter L., Bennett, John M., Lowenberg, Bob, Wijermans, Pierre W., Nimer, Stephen D., Pinto, Antonio, Beran, Miloslav, de Witte, Theo M., Stone, Richard M., Mittelman, Moshe, Sanz, Guillermo F., Gore, Steven D., Schiffer, Charles A., Kantarjian, Hagop

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Results of Treatment With Hyper-CVAD, a Dose-Intensive Regimen, in Adult Acute Lymphocytic Leukemia von KANTARJIAN, H. M, O'BRIEN, S, HA, C. S, KEATING, M. J, MURPHY, S, FREIREICH, E. J, SMITH, T. L, CORTES, J, GILES, F. J, BERAN, M, PIERCE, S, HUH, Y, ANDREEFF, M, KOLLER, C

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Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study von Kornblau, Steven M., Banker, Deborah E., Stirewalt, Derek, Shen, Danny, Lemker, Elizabeth, Verstovsek, Srdan, Estrov, Zeev, Faderl, Stefan, Cortes, Jorge, Beran, Miloslav, Jackson, C. Ellen, Chen, Wenjing, Estey, Elihu, Appelbaum, Frederick R.

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Long‐term follow‐up results of the combination of topotecan and cytarabine and other intensive chemotherapy regimens in myelodysplastic syndrome von Kantarjian, Hagop, Beran, Miloslav, Cortes, Jorge, O'Brien, Susan, Giles, Francis, Pierce, Sherry, Shan, Jianqin, Plunkett, William, Keating, Michael, Estey, Elihu

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Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias von Faderl, Stefan, Gandhi, Varsha, O'Brien, Susan, Bonate, Peter, Cortes, Jorge, Estey, Elihu, Beran, Miloslav, Wierda, William, Garcia-Manero, Guillermo, Ferrajoli, Alessandra, Estrov, Zeev, Giles, Francis J., Du, Min, Kwari, Monica, Keating, Michael, Plunkett, William, Kantarjian, Hagop

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Prognostic factors and scoring systems in chronic myelomonocytic leukemia: a retrospective analysis of 213 patients von Onida, Francesco, Kantarjian, Hagop M., Smith, Terry L., Ball, Greg, Keating, Michael J., Estey, Elihu H., Glassman, Armand B., Albitar, Maher, Kwari, Monica I., Beran, Miloslav

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Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center von Oki, Yasuhiro, Kantarjian, Hagop M., Zhou, Xian, Cortes, Jorge, Faderl, Stefan, Verstovsek, Srdan, O'Brien, Susan, Koller, Charles, Beran, Miloslav, Bekele, B. Nebiyou, Pierce, Sherry, Thomas, Deborah, Ravandi, Farhad, Wierda, William G., Giles, Francis, Ferrajoli, Alessandra, Jabbour, Elias, Keating, Michael J., Bueso-Ramos, Carlos E., Estey, Elihu, Garcia-Manero, Guillermo

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Effect of diagnosis (refractory anemia with excess blasts, refractory anemia with excess blasts in transformation, or acute myeloid leukemia [AML]) on outcome of AML-type chemother... von ESTEY, E, THALL, P, BERAN, M, KANTARJIAN, H, PIERCE, S, KEATING, M

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Engraftment of Allogeneic Hematopoietic Progenitor Cells With Purine Analog-Containing Chemotherapy: Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy von Giralt, Sergio, Estey, Elihu, Albitar, Maher, van Besien, Koen, Rondón, Gabriela, Anderlini, Paolo, O'Brien, Susan, Khouri, Issa, Gajewski, James, Mehra, Rakesh, Claxton, David, Andersson, Borje, Beran, Miloslav, Przepiorka, Donna, Koller, Charles, Kornblau, Steve, Körbling, Martin, Keating, Michael, Kantarjian, Hagop, Champlin, Richard

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Experience with gemtuzumab ozogamycin (“mylotarg”) and all-trans retinoic acid in untreated acute promyelocytic leukemia von Estey, Elihu H., Giles, Francis J., Beran, Miloslav, O'Brien, Susan, Pierce, Sherry A., Faderl, Stefan H., Cortes, Jorge E., Kantarjian, Hagop M.

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Phase I Study of BMS-214662, a Farnesyl Transferase Inhibitor in Patients With Acute Leukemias and High-Risk Myelodysplastic Syndromes von CORTES, Jorge, FADERL, Stefan, O'BRIEN, Susan, WRIGHT, John, BAI, Stephen A, KANTARJIAN, Hagop, ESTEY, Elihu, KURZROCK, Razelle, THOMAS, Deborah, BERAN, Miloslav, GARCIA-MANERO, Guillermo, FERRAJOLI, Alessandra, GILES, Francis, KOLLER, Charles

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Comparison of idarubicin + ara-C–, fludarabine + ara-C–, and topotecan + ara-C–based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess... von Estey, Elihu H., Thall, Peter F., Cortes, Jorge E., Giles, Francis J., O'Brien, Susan, Pierce, Sherry A., Wang, Xuemei, Kantarjian, Hagop M., Beran, Miloslav

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Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance von Chandra, Joya, Tracy, Jeannette, Loegering, David, Flatten, Karen, Verstovsek, Srdan, Beran, Miloslav, Gorre, Mercedes, Estrov, Zeev, Donato, Nicholas, Talpaz, Moshe, Sawyers, Charles, Bhalla, Kapil, Karp, Judith, Sausville, Edward, Kaufmann, Scott H.

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Gemtuzumab ozogamicin with or without interleukin 11 in patients 65 years of age or older with untreated acute myeloid leukemia and high-risk myelodysplastic syndrome: comparison w... von Estey, Elihu H., Thall, Peter F., Giles, Francis J., Wang, Xue-Mei, Cortes, Jorge E., Beran, Miloslav, Pierce, Sherry A., Thomas, Deborah A., Kantarjian, Hagop M.

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