The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection von Niu, Congrong, Livingston, Christine M, Li, Li, Beran, Rudolf K, Daffis, Stephane, Ramakrishnan, Dhivya, Burdette, Dara, Peiser, Leanne, Salas, Eduardo, Ramos, Hilario, Yu, Mei, Cheng, Guofeng, Strubin, Michel, Delaney, IV, William E, Fletcher, Simon P

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Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism von Niu, Congrong, Li, Li, Daffis, Stephane, Lucifora, Julie, Bonnin, Marc, Maadadi, Sarah, Salas, Eduardo, Chu, Ruth, Ramos, Hilario, Livingston, Christine M., Beran, Rudolf K., Garg, Abhishek V., Balsitis, Scott, Durantel, David, Zoulim, Fabien, Delaney, William E., Fletcher, Simon P.

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Understanding and Targeting HBV Transcription and Post-Transcriptional Regulation von Fletcher, Simon P, Beran, Rudolf K

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Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes von PHAN, Tung, BERAN, Rudolf K. F, PETERS, Christopher, LORENZ, Ivo C, LINDENBACH, Brett D

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Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes von Kornyeyev, Dmytro, Ramakrishnan, Dhivya, Voitenleitner, Christian, Livingston, Christine M, Xing, Weimei, Hung, Magdeleine, Kwon, Hyock Joo, Fletcher, Simon P, Beran, Rudolf K

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Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase von Beran, Rudolf K.F., Pyle, Anna Marie

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The Serine Protease Domain of Hepatitis C Viral NS3 Activates RNA Helicase Activity by Promoting the Binding of RNA Substrate von Beran, Rudolf K.F., Serebrov, Victor, Pyle, Anna Marie

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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP von DUMONT, Sophie, WEI CHENG, SEREBROV, Victor, BERAN, Rudolf K, TINOCO, Ignacio, PYLE, Anna Marie, BUSTAMANTE, Carlos

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The NS4A Protein of Hepatitis C Virus Promotes RNA-Coupled ATP Hydrolysis by the NS3 Helicase von BERAN, Rudolf K. F, LINDENBACH, Brett D, PYLE, Anna Marie

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Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6 von Livingston, Christine M, Ramakrishnan, Dhivya, Strubin, Michel, Fletcher, Simon P, Beran, Rudolf K

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The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication von LINDENBACH, Brett D, PRAGAI, Béla M, MONTSERRET, Roland, BERAN, Rudolf K. F, PYLE, Anna M, PENIN, Francois, RICE, Charles M

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In vitro resistance profile of hepatitis C virus NS5A inhibitor velpatasvir in genotypes 1 to 6 von Dvory‐Sobol, Hadas, Han, Bin, Lu, Julia, Yu, Mei, Beran, Rudolf K., Cheng, Guofeng, Martin, Ross, Svarovskaia, Evguenia, Mo, Hongmei

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Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor von Decorsière, Adrien, Mueller, Henrik, van Breugel, Pieter C., Abdul, Fabien, Gerossier, Laetitia, Beran, Rudolf K., Livingston, Christine M., Niu, Congrong, Fletcher, Simon P., Hantz, Olivier, Strubin, Michel

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Physical and functional interactions among RNase E, polynucleotide phosphorylase and the cold‐shock protein, CsdA: evidence for a ‘cold shock degradosome’ von Prud’homme‐Généreux, Annie, Beran, Rudolf K., Iost, Isabelle, Ramey, C. Shane, Mackie, George A., Simons, Robert W.

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A Small-Molecule Inhibitor of Hepatitis C Virus Infectivity von BUSH, Caroline O, POKROVSKII, Maria V, PAGRATIS, Nikos, WEIDONG ZHONG, DELANEY, William E, PAULSON, Matthew S, BERAN, Rudolf K. F, SAITO, Roland, MORGANELLI, Philip, CANALES, Eda, CLARKE, Michael O, LAZERWITH, Scott E, GOLDE, Justin, REID, Brian G, BABAOGLU, Kerim

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Cellular growth kinetics distinguish a cyclophilin inhibitor from an HSP90 inhibitor as a selective inhibitor of hepatitis C virus von Beran, Rudolf K F, Sharma, Ruchi, Corsa, Amoreena C, Tian, Yang, Golde, Justin, Lundgaard, Greta, Delaney, 4th, William E, Zhong, Weidong, Greenstein, Andrew E

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Establishing a Mechanistic Basis for the Large Kinetic Steps of the NS3 Helicase von Serebrov, Victor, Beran, Rudolf K.F., Pyle, Anna Marie

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Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo von Allweiss, Lena, Giersch, Katja, Pirosu, Andrea, Volz, Tassilo, Muench, Robert C, Beran, Rudolf K, Urban, Stephan, Javanbakht, Hassan, Fletcher, Simon P, Lütgehetmann, Marc, Dandri, Maura

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Hepatitis C viral entry inhibitors prolong viral suppression by replication inhibitors in persistently-infected Huh7 cultures von Bush, Caroline O, Greenstein, Andrew E, Delaney, 4th, William E, Beran, Rudolf K F

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Novel Mutations in a Tissue Culture-Adapted Hepatitis C Virus Strain Improve Infectious-Virus Stability and Markedly Enhance Infection Kinetics von POKROVSKII, Maria V, BUSH, Caroline O, PAULSON, Matthew S, BERAN, Rudolf K. F, ROBINSON, Margaret F, GUOFENG CHENG, TIRUNAGARI, Neeraj, FENAUX, Martijn, GREENSTEIN, Andrew E, WEIDONG ZHONG, DELANEY, William E

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