Quantification of Drug Molecules in Live Single Cells Using the Single-Probe Mass Spectrometry Technique von Pan, Ning, Standke, Shawna J, Kothapalli, Naga Rama, Sun, Mei, Bensen, Ryan C, Burgett, Anthony W. G, Yang, Zhibo

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Mass Spectrometry Measurement of Single Suspended Cells Using a Combined Cell Manipulation System and a Single-Probe Device von Standke, Shawna J, Colby, Devon H, Bensen, Ryan C, Burgett, Anthony W. G, Yang, Zhibo

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TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin von Torres-Ayuso, Pedro, An, Elvira, Nyswaner, Katherine M, Bensen, Ryan C, Ritt, Daniel A, Specht, Suzanne I, Das, Sudipto, Andresson, Thorkell, Cachau, Raul E, Liang, Roger J, Ries, Amy L, Robinson, Christina M, Difilippantonio, Simone, Gouker, Brad, Bassel, Laura, Karim, Baktiar O, Miller, Chad J, Turk, Benjamin E, Morrison, Deborah K, Brognard, John

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Differing activities of oxysterol-binding protein (OSBP) targeting anti-viral compounds von Roberts, Brett L., Severance, Zachary C., Bensen, Ryan C., Le-McClain, Anh T., Malinky, Cori A., Mettenbrink, Evan M., Nuñez, Juan I., Reddig, William J., Blewett, Earl L., Burgett, Anthony W.G.

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Transient Compound Treatment Induces a Multigenerational Reduction of Oxysterol-Binding Protein (OSBP) Levels and Prophylactic Antiviral Activity von Roberts, Brett L, Severance, Zachary C, Bensen, Ryan C, Le, Anh T, Kothapalli, Naga Rama, Nuñez, Juan I, Ma, Hongyan, Wu, Si, Standke, Shawna J, Yang, Zhibo, Reddig, William J, Blewett, Earl L, Burgett, Anthony W. G

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FgaPT2, a biocatalytic tool for alkyl-diversification of indole natural products von Bandari, Chandrasekhar, Scull, Erin M, Bavineni, Tejaswi, Nimmo, Susan L, Gardner, Eric D, Bensen, Ryan C, Burgett, Anthony W, Singh, Shanteri

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Small Molecule Targeting of Oxysterol-Binding Protein (OSBP)-Related Protein 4 and OSBP Inhibits Ovarian Cancer Cell Proliferation in Monolayer and Spheroid Cell Models von Bensen, Ryan C, Gunay, Gokhan, Finneran, Matthew C, Jhingan, Isha, Acar, Handan, Burgett, Anthony W. G

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Comparative Genomic Analysis of Archaeal Genotypic Variants in a Single Population and in Two Different Oceanic Provinces von BEJA, Oded, KOONIN, Eugene V, ARAVIND, L, TAYLOR, Lance T, SEITZ, Heidi, STEIN, Jefferey L, BENSEN, Daniel C, FELDMAN, Robert A, SWANSON, Ronald V, DELONG, Edward F

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Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents von Tari, Leslie W, Li, Xiaoming, Trzoss, Michael, Bensen, Daniel C, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Lee, Suk Joong, Hough, Grayson, Phillipson, Doug, Akers-Rodriguez, Suzanne, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Castellano, Amanda, Locke, Jeff B, Brown-Driver, Vickie, Murphy, Timothy M, Ong, Voon S, Pillar, Chris M, Shinabarger, Dean L, Nix, Jay, Lightstone, Felice C, Wong, Sergio E, Nguyen, Toan B, Shaw, Karen J, Finn, John

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Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia von Hudkins, Robert L., Allen, Eric, Balcer, Alexandra, Hoffman, Isaac D., Iyer, Samhita, Neal, Melissa, Nelson, Kirk J., Rideout, Marc, Ye, Qing, Starrett, Jacqueline H., Patel, Piyush, Harris, Todd, Swanson, Ronald V., Bensen, Daniel C.

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Structure–Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4 von Severance, Zachary C., Nuñez, Juan I., Le-McClain, Anh T., Malinky, Cori A., Bensen, Ryan C., Fogle, Robert S., Manginelli, Gianni W., Sakers, Sophia H., Falcon, Emily C., Bui, Richard Hoang, Snead, Kevin J., Bourne, Christina R., Burgett, Anthony W. G.

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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spe... von Tari, Leslie W., Trzoss, Michael, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Nix, Jay, Finn, John

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Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE), Part II: Development of inhibitors with broad spectrum, Gram-negative antibacterial activity von Trzoss, Micheal, Bensen, Daniel C., Li, Xiaoming, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Creighton, Christopher J., Cunningham, Mark L., Kwan, Bryan, Stidham, Mark, Nelson, Kirk, Brown-Driver, Vickie, Castellano, Amanda, Shaw, Karen J., Lightstone, Felice C., Wong, Sergio E., Nguyen, Toan B., Finn, John, Tari, Leslie W.

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What Determines Support for Donor Registration Systems? The Influence of Sociopolitical Viewpoint, Attitudes Toward Organ Donation, and Patients’ Need von Dijker, Anton J. M., de Bakker, Erica, Bensen, Stanneke C., de Vries, Nanne K.

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Integrated Cell Manipulation Platform Coupled with the Single-probe for Mass Spectrometry Analysis of Drugs and Metabolites in Single Suspension Cells von Standke, Shawna J, Colby, Devon H, Bensen, Ryan C, Burgett, Anthony W G, Yang, Zhibo

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Single Cell Mass Spectrometry Quantification of Anticancer Drugs: Proof of Concept in Cancer Patients von Bensen, Ryan C, Standke, Shawna J, Colby, Devon H, Kothapalli, Naga Rama, Le-McClain, Anh T, Patten, Michael A, Tripathi, Abhishek, Heinlen, Jonathan E, Yang, Zhibo, Burgett, Anthony W. G

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Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin von Bensen, D. C., Rodriguez, S., Nix, J., Cunningham, M. L., Tari, L. W.

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Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a Macromolecular Synthesis Assay von Cunningham, Mark L., Kwan, Bryan P., Nelson, Kirk J., Bensen, Daniel C., Shaw, Karen J.

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Radiologic and Pathologic Correlation Using a Commercially Available MRI-Guided Transperineal Prostate Biopsy Planning System von Hsi, R.A., Schulze, K., Bildsten, S., Bensen, C., Sabolch, A., Li, A., Henne, M.

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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors von Tari, Leslie W., Hoffman, Isaac D., Bensen, Daniel C., Hunter, Michael J., Nix, Jay, Nelson, Kirk J., McRee, Duncan E., Swanson, Ronald V.

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