Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion von Papa, Guido, Mallery, Donna L, Albecka, Anna, Welch, Lawrence G, Cattin-Ortolá, Jérôme, Luptak, Jakub, Paul, David, McMahon, Harvey T, Goodfellow, Ian G, Carter, Andrew, Munro, Sean, James, Leo C

Volltext

Reduced neutralisation of the Delta (B.1.617.2) SARS-CoV-2 variant of concern following vaccination von Davis, Chris, Logan, Nicola, Tyson, Grace, Orton, Richard, Harvey, William T, Perkins, Jonathan S, Mollett, Guy, Blacow, Rachel M, Peacock, Thomas P, Barclay, Wendy S, Cherepanov, Peter, Palmarini, Massimo, Murcia, Pablo R, Patel, Arvind H, Robertson, David L, Haughney, John, Thomson, Emma C, Willett, Brian J

Volltext

Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2 von Ou, Tianling, Mou, Huihui, Zhang, Lizhou, Ojha, Amrita, Choe, Hyeryun, Farzan, Michael

Volltext

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells von Patra, Tapas, Meyer, Keith, Geerling, Lizzie, Isbell, T Scott, Hoft, Daniel F, Brien, James, Pinto, Amelia K, Ray, Ratna B, Ray, Ranjit

Volltext

A novel cell culture system modeling the SARS-CoV-2 life cycle von Ju, Xiaohui, Zhu, Yunkai, Wang, Yuyan, Li, Jingrui, Zhang, Jiaxing, Gong, Mingli, Ren, Wenlin, Li, Sai, Zhong, Jin, Zhang, Linqi, Zhang, Qiangfeng Cliff, Zhang, Rong, Ding, Qiang

Volltext

Dating first cases of COVID-19 von Roberts, David L, Rossman, Jeremy S, Jaric, Ivan

Volltext

Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression von Zheng, Huiwen, Li, Heng, Guo, Lei, Liang, Yan, Li, Jing, Wang, Xi, Hu, Yunguang, Wang, Lichun, Liao, Yun, Yang, Fengmei, Li, Yanyan, Fan, Shengtao, Li, Dandan, Cui, Pingfang, Wang, Qingling, Shi, Haijing, Chen, Yanli, Yang, Zening, Yang, Jinling, Shen, Dong, Cun, Wei, Zhou, Xiaofang, Dong, Xingqi, Wang, Yunchuan, Chen, Yong, Dai, Qing, Jin, Weihua, He, Zhanlong, Li, Qihan, Liu, Longding

Volltext

Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection von Echavarría-Consuegra, Liliana, Cook, Georgia M, Busnadiego, Idoia, Lefèvre, Charlotte, Keep, Sarah, Brown, Katherine, Doyle, Nicole, Dowgier, Giulia, Franaszek, Krzysztof, Moore, Nathan A, Siddell, Stuart G, Bickerton, Erica, Hale, Benjamin G, Firth, Andrew E, Brierley, Ian, Irigoyen, Nerea

Volltext

Breadth and function of antibody response to acute SARS-CoV-2 infection in humans von Huang, Kuan-Ying A, Tan, Tiong Kit, Chen, Ting-Hua, Huang, Chung-Guei, Harvey, Ruth, Hussain, Saira, Chen, Cheng-Pin, Harding, Adam, Gilbert-Jaramillo, Javier, Liu, Xu, Knight, Michael, Schimanski, Lisa, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Jan, Jia-Tsrong, Ma, Che, James, William, Daniels, Rodney S, McCauley, John W, Rijal, Pramila, Townsend, Alain R

Volltext

Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors von Prabhakara, Chaitra, Godbole, Rashmi, Sil, Parijat, Jahnavi, Sowmya, Gulzar, Shah-E-Jahan, van Zanten, Thomas S, Sheth, Dhruv, Subhash, Neeraja, Chandra, Anchal, Shivaraj, Akshatha, Panikulam, Patricia, U, Ibrahim, Nuthakki, Vijay Kumar, Puthiyapurayil, Theja Parassini, Ahmed, Riyaz, Najar, Ashaq Hussain, Lingamallu, Sai Manoz, Das, Snigdhadev, Mahajan, Bhagyashri, Vemula, Praveen, Bharate, Sandip B, Singh, Parvinder Pal, Vishwakarma, Ram, Guha, Arjun, Sundaramurthy, Varadharajan, Mayor, Satyajit

Volltext

Infectious viral shedding of SARS-CoV-2 Delta following vaccination: A longitudinal cohort study von Garcia-Knight, Miguel, Anglin, Khamal, Tassetto, Michel, Lu, Scott, Zhang, Amethyst, Goldberg, Sarah A, Catching, Adam, Davidson, Michelle C, Shak, Joshua R, Romero, Mariela, Pineda-Ramirez, Jesus, Diaz-Sanchez, Ruth, Rugart, Paulina, Donohue, Kevin, Massachi, Jonathan, Sans, Hannah M, Djomaleu, Manuella, Mathur, Sujata, Servellita, Venice, McIlwain, David, Gaudiliere, Brice, Chen, Jessica, Martinez, Enrique O, Tavs, Jacqueline M, Bronstone, Grace, Weiss, Jacob, Watson, John T, Briggs-Hagen, Melissa, Abedi, Glen R, Rutherford, George W, Deeks, Steven G, Chiu, Charles, Saydah, Sharon, Peluso, Michael J, Midgley, Claire M, Martin, Jeffrey N, Andino, Raul, Kelly, J Daniel

Volltext

TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2 von Trimarco, Joseph D., Heaton, Brook E., Chaparian, Ryan R., Burke, Kaitlyn N., Binder, Raquel A., Gray, Gregory C., Smith, Clare M., Menachery, Vineet D., Heaton, Nicholas S.

Volltext

Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolv... von Heide, Janna, Schulte, Sophia, Kohsar, Matin, Brehm, Thomas Theo, Herrmann, Marissa, Karsten, Hendrik, Marget, Matthias, Peine, Sven, Johansson, Alexandra M, Sette, Alessandro, Lütgehetmann, Marc, Kwok, William W, Sidney, John, Schulze Zur Wiesch, Julian

Volltext

Detection of R.1 lineage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with spike protein W152L/E484K/G769V mutations in Japan von Hirotsu, Yosuke, Omata, Masao

Volltext

Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19 von Rodriguez, Christophe, de Prost, Nicolas, Fourati, Slim, Lamoureux, Claudie, Gricourt, Guillaume, N'debi, Melissa, Canoui-Poitrine, Florence, Désveaux, Isaac, Picard, Oriane, Demontant, Vanessa, Trawinski, Elisabeth, Lepeule, Raphaël, Surgers, Laure, Vindrios, William, Lelièvre, Jean-Daniel, Mongardon, Nicolas, Langeron, Olivier, Cohen, José L, Mekontso-Dessap, Armand, Woerther, Paul-Louis, Pawlotsky, Jean-Michel

Volltext

Nasal delivery of single-domain antibody improves symptoms of SARS-CoV-2 infection in an animal model von Haga, Kei, Takai-Todaka, Reiko, Matsumura, Yuta, Song, Chihong, Takano, Tomomi, Tojo, Takuto, Nagami, Atsushi, Ishida, Yuki, Masaki, Hidekazu, Tsuchiya, Masayuki, Ebisudani, Toshiki, Sugimoto, Shinya, Sato, Toshiro, Yasuda, Hiroyuki, Fukunaga, Koichi, Sawada, Akihito, Nemoto, Naoto, Murata, Kazuyoshi, Morimoto, Takuya, Katayama, Kazuhiko

Volltext

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2 von Mou, Huihui, Quinlan, Brian D, Peng, Haiyong, Liu, Guanqun, Guo, Yan, Peng, Shoujiao, Zhang, Lizhou, Davis-Gardner, Meredith E, Gardner, Matthew R, Crynen, Gogce, DeVaux, Lindsey B, Voo, Zhi Xiang, Bailey, Charles C, Alpert, Michael D, Rader, Christoph, Gack, Michaela U, Choe, Hyeryun, Farzan, Michael

Volltext

ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions von Rawle, Daniel J, Le, Thuy T, Dumenil, Troy, Yan, Kexin, Tang, Bing, Nguyen, Wilson, Watterson, Daniel, Modhiran, Naphak, Hobson-Peters, Jody, Bishop, Cameron, Suhrbier, Andreas

Volltext

Inactivated rabies virus vectored SARS-CoV-2 vaccine prevents disease in a Syrian hamster model von Kurup, Drishya, Malherbe, Delphine C, Wirblich, Christoph, Lambert, Rachael, Ronk, Adam J, Zabihi Diba, Leila, Bukreyev, Alexander, Schnell, Matthias J

Volltext

Niclosamide is a proton carrier and targets acidic endosomes with broad antiviral effects von Jurgeit, Andreas, McDowell, Robert, Moese, Stefan, Meldrum, Eric, Schwendener, Reto, Greber, Urs F

Volltext