P429: CLONALLY RESOLVED SINGLE‐CELL MULTI‐OMICS IDENTIFIES LEUKEMIA SURFACE ANTIGENS von Merbach, A. K., Beneyto‐Calabuig, S., Kniffka, J.‐A., Szu‐Tu, C., Rohde, C., Antes, M., Janssen, M., Waclawiczek, A., Landry, J. J. M., Benes, V., Anna, J., Brough, M., Besenbeck, B., Felden, J., Bäumer, S., Hundemer, M., Sauer, T., Pabst, C., Scherer, M., Raffel, S., Velten, L., Müller‐Tidow, C.

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Late-onset NPM1 mutation in a MYC-amplified relapsed/refractory acute myeloid leukemia patient treated with gemtuzumab ozogamicin and glasdegib von Jaramillo, Sonia, Scherer, Michael, Szu-Tu, Chelsea, Beneyto-Calabuig, Sergi, Müller-Tidow, Carsten, Schlenk, Richard F, Hundemer, Michael, Velten, Lars, Pabst, Caroline

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P323: UNCOVERING SUBCLONAL METABOLIC VULNERABILITIES IN ACUTE LYMPHOBLASTIC LEUKEMIA AT SINGLE CELL RESOLUTION von Mönnig, Maximilian, Antes, Magdalena, Beneyto‐Calabuig, Sergi, Vonficht, Dominik, Marot‐Lassauzaie, Valérie, Besiriduo, Eleni, Müller‐Tidow, Carsten, Haghverdi, Laleh, Haas, Simon, Velten, Lars, Raffel, Simon

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Integrative single‐cell expression and functional studies unravels a sensitization to cytarabine‐based chemotherapy through HIF pathway inhibition in AML leukemia stem cells von Velasco‐Hernandez, Talia, Trincado, Juan L., Vinyoles, Meritxell, Closa, Adria, Martínez‐Moreno, Alba, Gutiérrez‐Agüera, Francisco, Molina, Oscar, Rodríguez‐Cortez, Virginia C., Ximeno‐Parpal, Pau, Fernández‐Fuentes, Narcís, Petazzi, Paolo, Beneyto‐Calabuig, Sergi, Velten, Lars, Romecin, Paola, Casquero, Raquel, Abollo‐Jiménez, Fernando, Guardia, Rafael D., Lorden, Patricia, Bataller, Alex, Lapillonne, Hélène, Stam, Ronald W., Vives, Susana, Torrebadell, Montserrat, Fuster, Jose L., Bueno, Clara, Sarry, Jean‐Emmanuel, Eyras, Eduardo, Heyn, Holger, Menéndez, Pablo

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P470: SINGLE‐CELL METABOLIC MULTIOMICS TO IDENTIFY VULNERABILITIES IN ACUTE MYELOID LEUKEMIA STEM CELLS von Antes, Magdalena, Besiridou, Eleni, Mönnig, Maximilian, Beneyto Calabuig, Sergi, Trumpp, Andreas, Müller‐Tidow, Carsten, Haas, Simon, Velten, Lars, Raffel, Simon

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Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia von Beneyto Calabuig, Sergi, Szu-Tu, Chelsea, Velten, Lars

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Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data von Marot-Lassauzaie, Valérie, Beneyto Calabuig, Sergi, Obermayer, Benedikt, Velten, Lars, Beule, Dieter, Haghverdi, Laleh

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Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data von Marot-Lassauzaie, Valérie, Beneyto-Calabuig, Sergi, Obermayer, Benedikt, Velten, Lars, Beule, Dieter, Haghverdi, Laleh

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Investigating cellular hierarchies in acute myeloid leukemia using single-cell genomics von Beneyto Calabuig, Sergi

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Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia von Beneyto-Calabuig, Sergi, Merbach, Anne Kathrin, Kniffka, Jonas-Alexander, Antes, Magdalena, Szu-Tu, Chelsea, Rohde, Christian, Waclawiczek, Alexander, Stelmach, Patrick, Gräßle, Sarah, Pervan, Philip, Janssen, Maike, Landry, Jonathan J.M., Benes, Vladimir, Jauch, Anna, Brough, Michaela, Bauer, Marcus, Besenbeck, Birgit, Felden, Julia, Bäumer, Sebastian, Hundemer, Michael, Sauer, Tim, Pabst, Caroline, Wickenhauser, Claudia, Angenendt, Linus, Schliemann, Christoph, Trumpp, Andreas, Haas, Simon, Scherer, Michael, Raffel, Simon, Müller-Tidow, Carsten, Velten, Lars

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Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells von Velasco Hernandez, Talia, Beneyto Calabuig, Sergi, Velten, Lars, Lorden, Patricia, Eyras Jiménez, Eduardo, Heyn, Holger, Menéndez, Pablo

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A global genetic interaction network by single-cell imaging and machine learning von Heigwer, Florian, Scheeder, Christian, Bageritz, Josephine, Yousefian, Schayan, Rauscher, Benedikt, Laufer, Christina, Beneyto-Calabuig, Sergi, Funk, Maja Christina, Peters, Vera, Boulougouri, Maria, Bilanovic, Jana, Miersch, Thilo, Schmitt, Barbara, Blass, Claudia, Port, Fillip, Boutros, Michael

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Seurat SmartSeq A.10-12 von Velten, Lars, Beneyto-Calabuig, Sergi

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Seurat more cells A.2 von Velten, Lars, Beneyto-Calabuig, Sergi

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Seurat more cells A.9 von Velten, Lars, Beneyto-Calabuig, Sergi

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MAIN DATASET: Seurat CloneTracer Cohort von Velten, Lars, Beneyto-Calabuig, Sergi

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CloneTracer output von Velten, Lars, Beneyto-Calabuig, Sergi

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Supplementary Data for "Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance" von Sumiko Takao, Richard Koche, Beneyto Calabuig, Sergi, Velten, Lars, Alex Kentsis

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