Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism von Benej, Martin, Hong, Xiangqian, Vibhute, Sandip, Scott, Sabina, Wu, Jinghai, Graves, Edward, Le, Quynh-Thu, Koong, Albert C., Giaccia, Amato J., Yu, Bing, Chen, Shih-Ching, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Carbonic Anhydrase IX: Regulation and Role in Cancer von Benej, Martin, Pastorekova, Silvia, Pastorek, Jaromir

Volltext

CA IX Stabilizes Intracellular pH to Maintain Metabolic Reprogramming and Proliferation in Hypoxia von Benej, Martin, Svastova, Eliska, Banova, Radivojka, Kopacek, Juraj, Gibadulinova, Adriana, Kery, Martin, Arena, Simona, Scaloni, Andrea, Vitale, Monica, Zambrano, Nicola, Papandreou, Ioanna, Denko, Nicholas C., Pastorekova, Silvia

Volltext

Dynamic regulation of mitochondrial pyruvate metabolism is necessary for orthotopic pancreatic tumor growth von Ruiz, Nancy P. Echeverri, Mohan, Vijay, Wu, Jinghai, Scott, Sabina, Kreamer, McKenzie, Benej, Martin, Golias, Tereza, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity von Kaul, Kirti, Benej, Martin, Mishra, Sanjay, Ahirwar, Dinesh K., Yadav, Marshleen, Stanford, Kristin I., Jacob, Naduparambil K., Denko, Nicholas C., Ganju, Ramesh K.

Volltext

Quantitative Proteomics Reveal Peroxiredoxin Perturbation Upon Persistent Lymphocytic Choriomeningitis Virus Infection in Human Cells von Benej, Martin, Danchenko, Maksym, Oveckova, Ingrid, Cervenak, Filip, Tomaska, Lubomir, Grossmannova, Katarina, Polcicova, Katarina, Golias, Tereza, Tomaskova, Jana

Volltext

Algomaster Platform Extension for Improved Usability von Benej, Martin, Simonak, Slavomir

Volltext

Hypoxic adaptation of mitochondria and its impact on tumor cell function von Benej, Martin, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Unanticipated metabolic plasticity in response to chronic hypoxia von Papandreou, Ioanna, Benej, Martin, Denko, Nicholas C.

Volltext

Abstract 3067: Exploring strategies to modulate mitochondrial metabolism to alleviate tumor hypoxia von Benej, Martin, Wu, Jinghai, Kreamer, McKenzie, Vibhute, Sandip, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Abstract PO-033: Papaverine derivative smv-32 alleviates tumor hypoxia and radiosensitizes tumors by inhibiting mitochondrial metabolism von Benej, Martin, Wu, Jinghai, Kreamer, McKenzie, Vibhute, Sandip, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Abstract 983: Metabolic radiosensitization: Overcoming the radioresistance of hypoxic tumors by targeting OXPHOS von Benej, Martin, Hong, Xiangqian, Yu, Bing, Papandreou, Ioanna, Denko, Nicholas

Volltext

Abstract 5467: Phosphoproteomic analysis of pyruvate dehydrogenase in response to environmental stress von O'Neill, Wendi, Golias, Tereza, Benej, Martin, Denko, Nicholas

Volltext

Abstract 5841: Hypoxic tumors can be sensitized to radiation therapy by repurposing papaverine as an inhibitor of mitochondrial respiration von Benej, Martin, Papandreou, Ioanna, Hong, Xiangqian, Yu, Bing, Denko, Nicholas

Volltext

Abstract 233: Tumor-associated carbonic anhydrase IX maintains cellular proliferation by regulating tumor metabolism: a novel link revealed by proteomics von Benej, Martin, Svastova, Eliska, Banova, Radivojka, Kopacek, Juraj, Gibadulinova, Adriana, Kery, Martin, Arena, Simona, Scaloni, Andrea, Vitale, Monica, Zambrano, Nicola, Papandreou, Ioanna, Denko, Nicholas C., Pastorekova, Silvia

Volltext

Effect of glucose concentration and cryopreservation on mitochondrial functions of bull spermatozoa and relationship with sire conception rate von Moraes, Christa R., Moraes, Luis E., Blawut, Bryan, Benej, Martin, Papandreou, Ioanna, Denko, Nicholas C., Coutinho da Silva, Marco

Volltext

Abstract 4832: Copy number amplification of OXPHOS genes drives tumor hypoxia in NSCLC von Benej, Martin, Benejova, Katarina, Kreamer, McKenzie, Wu, Jinghai, Ashraf, Syed, Wheeler, Caroline, Hoyd, Rebecca, Spakowicz, Daniel, Denko, Nicholas C.

Volltext

Abstract 2927: Papaverine and its novel derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism von Benej, Martin, Hong, Xiangqian, Vibhute, Sandip, Scott, Sabina, Wu, Jinghai, Graves, Edward, Le, Quynh-Thu, Koong, Albert C., Giaccia, Amato J., Chen, Ching-Shih, Yu, Bing, Papandreou, Ioanna, Denko, Nicholas C.

Volltext

Pharmacological Regulation of Tumor Hypoxia in Model Murine Tumors and Spontaneous Canine Tumors von Benej, Martin, Wu, Jinghai, Kreamer, McKenzie, Kery, Martin, Corrales-Guerrero, Sergio, Papandreou, Ioanna, Williams, Terence M., Li, Zihai, Graves, Edward E., Selmic, Laura E., Denko, Nicholas C.

Volltext

Encapsulation of anti-carbonic anhydrase IX antibody in hydrogel microspheres for tumor targeting von Takacova, Martina, Hlouskova, Gabriela, Zatovicova, Miriam, Benej, Martin, Sedlakova, Olga, Kopacek, Juraj, Pastorek, Jaromir, Lacik, Igor, Pastorekova, Silvia

Volltext