SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Soli... von Gonzalez-Junca, Alba, Liu, Frances D, Nagaraja, Archana S, Mullenix, Alyssa, Lee, Chen-Ting, Gordley, Russell M, Frimannsson, Daniel O, Maller, Ori, Garrison, Brian S, Iyer, Dharini, Benabbas, Anissa, Truong, Tiffany A, Quach, Allison, Tian, Mengxi, Martinez, Rowena, Savur, Rishi, Perry-McNamara, Alyssa, Nguyen, Denny, Almudhfar, Niran, Blanco, Carmina, Huynh, Christina, Nand, Asish, Lay, Yu-An E, Magal, Ashita, Mangalampalli, Sravani, Lee, Philip J, Lu, Timothy K, Lee, Gary

Volltext

Abstract 4246: SENTI-101, a novel genetically modified allogeneic cell product expressing IL12 and IL21, elicits a tumor-localized, robust, and multimodal immune response in precli... von Gonzalez, Alba, Liu, Frances D., Nagaraja, Archana, Mullenix, Alyssa, Gordley, Russell M., Frimannsson, Daniel O., Benabbas, Anissa, Lee, Chen-Ting, Truong, Tiffany A., Quach, Allison, Tian, Mengxi, Martinez, Rowena, Savur, Rishi, Perry-McNamara, Alyssa, Wang, Don-Hong, Maller, Ori, Iyer, Dharini, Magal, Ashita, Mangalampalli, Sravani, Huynh, Christina J., Blanco, Carmina C., Lin, Jack T., Garrison, Brian S., Lee, Philip, Lu, Timothy K., Lee, Gary

Volltext