A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans von Bejar, Cynthia A., Goyal, Shiwali, Afzal, Shoaib, Mangino, Massimo, Zhou, Ang, van der Most, Peter J., Bao, Yanchun, Gupta, Vipin, Smart, Melissa C., Walia, Gagandeep K., Verweij, Niek, Power, Christine, Prabhakaran, Dorairaj, Singh, Jai Rup, Mehra, Narinder K., Wander, Gurpreet S., Ralhan, Sarju, Kinra, Sanjay, Kumari, Meena, de Borst, Martin H., Hypponen, Elina, Spector, Tim D., Nordestgaard, Borge G., Blackett, Piers R., Sanghera, Dharambir K.

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1639-P: Effect of Educational Status on Fasting Glucose and HbA1c Concentrations Independent of Income and Population Differences in Indian Populations von KOSHY, TEENA, ARYA, RECTOR, LOPEZ-ALVARENGA, JUAN C., VENKATESAN, VETTRISELVI, RAVICHANDRAN, UMARANI, SHARMA, SURENDRA, LODHA, SAILESH, PONNALA, AMARESH REDDY, SHARMA, KRISHNA KUMAR, SHAIK, MAHABOOB VALI, RESENDEZ, ROY G., RAMU, DEEPIKA, VENUGOPAL, PRIYANKA, PARTHASARATHY, R., NOELTA, S., EZEILO, JULIET A., BEJAR, CYNTHIA A., MUMMIDI, SRINIVAS, NATESAN, CHIDAMBARAM, BLANGERO, JOHN, MEDICHERLA, KRISHNA M., THANIKACHALAM, SADAGOPAN, PANCHATCHARAM, THYAGARAJAN SADRAS, DILEEP KUMAR, K., GUPTA, RAJEEV, DUGGIRALA, RAVINDRANATH, SANGHERA, DHARAMBIR K., SOLOMON, FRANKLIN PAUL

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1717-P: Burden of Type 2 Diabetes and Its Genetic Determinants in Indian Populations: Findings from the INDIGENIUS Consortium von VENKATESAN, VETTRISELVI, LOPEZ-ALVARENGA, JUAN C., ARYA, RECTOR, KOSHY, TEENA, RAVICHANDRAN, UMARANI, SHARMA, SURENDRA, LODHA, SAILESH, PONNALA, AMARESH REDDY, SHARMA, KRISHNA KUMAR, SHAIK, MAHABOOB VALI, RESENDEZ, ROY G., RAMU, DEEPIKA, VENUGOPAL, PRIYANKA, R., PARTHASARATHY, S., NOELTA, EZEILO, JULIET A., BEJAR, CYNTHIA A., MUMMIDI, SRINIVAS, NATESAN, CHIDAMBARAM, BLANGERO, JOHN, MEDICHERLA, KRISHNA M., THANIKACHALAM, SADAGOPAN, PANCHATCHARAM, THYAGARAJAN SADRAS, K., DILEEP KUMAR, GUPTA, RAJEEV, SANGHERA, DHARAMBIR K., DUGGIRALA, RAVINDRANATH, PAUL, SOLOMON FRANKLIN

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A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans von Bejar, Cynthia A, Goyal, Shiwali, Afzal, Shoaib, Mangino, Massimo, Zhou, Ang, van der Most, Peter J, Bao, Yanchun, Gupta, Vipin, Smart, Melissa C, Walia, Gagandeep K, Verweij, Niek, Power, Christine, Prabhakaran, Dorairaj, Singh, Jai Rup, Mehra, Narinder K, Wander, Gurpreet S, Ralhan, Sarju, Kinra, Sanjay, Kumari, Meena, de Borst, Martin H, Hyppönen, Elina, Spector, Tim D, Nordestgaard, Børge G, Blackett, Piers R, Sanghera, Dharambir K

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Abstract TP518: Ethnic Differences in Poor Metabolizer Alleles of 12 Pharmacogenomic Actionable Genes in Asian Indians von Sanghera, Dharambir S, Bejar, Cynthia

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Obesity genetics and cardiometabolic health: Potential for risk prediction von Sanghera, Dharambir K., Bejar, Cynthia, Sharma, Sonali, Gupta, Rajeev, Blackett, Piers R.

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Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition von Sanghera, Dharambir K, Hopkins, Ruth, Malone-Perez, Megan W, Bejar, Cynthia, Tan, Chengcheng, Mussa, Huda, Whitby, Paul, Fowler, Ben, Rao, Chinthapally V, Fung, KarMing A, Lightfoot, Stan, Frazer, J Kimble

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Frequencies of poor metabolizer alleles of 12 pharmacogenomic actionable genes in Punjabi Sikhs of Indian Origin von Sanghera, Dharambir K., Bejar, Cynthia, Sapkota, Bishwa, Wander, Gurpreet S., Ralhan, Sarju

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Abstract TP95: Novel Biomarkers of Acute Ischemic Stroke Using MicroRNA Analysis von King, Jason, Sidorov, Evgeny, Vanamala, Jairam, Bejar, Cynthia, Indukuri, Vijay, Reddivari, Lavanya, Chainakul, Juliane, Bappaditya, Ray, Sanghera, Dharambir, Jorge, Ortiz Garcia

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Potential Metabolite Biomarkers for Acute Versus Chronic Stage of Ischemic Stroke: A Pilot Study von Sidorov, Evgeny, Bejar, Cynthia, Xu, Chao, Ray, Bappaditya, Reddivari, Lavanya, Chainakul, Juliane, Vanamala, Jairam K.P., Sanghera, Dharambir K.

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Abstract TP251: Metabolomic Biomarker Predictors of Infarct Size in Acute Ischemic Stroke von Beaver, Bahar M, Indukuri, Vijay V, Bejar, Cynthia, Sanghera, Dharambir, Reddivari, Lavanya, Apple, Blair, Xu, Chao, Ray, Bappaditya, Vanamala, Jairam K, Sidorov, Evgeny

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Novel Metabolites as Potential Indicators of Ischemic Infarction Volume: a Pilot Study von Sidorov, Evgeny V., Bejar, Cynthia, Xu, Chao, Ray, Bappaditya, Gordon, David, Chainakul, Juliane, Sanghera, Dharambir K.

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Burden of Type 2 Diabetes and Associated Cardiometabolic Traits and Their Heritability Estimates in Endogamous Ethnic Groups of India: Findings From the INDIGENIUS Consortium von Venkatesan, Vettriselvi, Lopez-Alvarenga, Juan Carlos, Arya, Rector, Ramu, Deepika, Koshy, Teena, Ravichandran, Umarani, Ponnala, Amaresh Reddy, Sharma, Surendra K, Lodha, Sailesh, Sharma, Krishna K, Shaik, Mahaboob Vali, Resendez, Roy G, Venugopal, Priyanka, R, Parthasarathy, Saju, Noelta, Ezeilo, Juliet A, Bejar, Cynthia, Wander, Gurpreet S, Ralhan, Sarju, Singh, Jai Rup, Mehra, Narinder K, Vadlamudi, Raghavendra Rao, Almeida, Marcio, Mummidi, Srinivas, Natesan, Chidambaram, Blangero, John, Medicherla, Krishna M, Thanikachalam, Sadagopan, Panchatcharam, Thyagarajan Sadras, Kandregula, Dileep Kumar, Gupta, Rajeev, Sanghera, Dharambir K, Duggirala, Ravindranath, Paul, Solomon F D

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Outcomes of pediatric cancer patients enrolled in phase 1 clinical trials designed for adults: Experience from a major cancer center von Subbiah, Vivek, Corrales-Medina, Fernando F., Herzog, Cynthia E., Hess, Kenneth R., Egas Bejar, Daniela Elizabeth, Hong, David S., Falchook, Gerald Steven, Anderson, Peter Meade, Nunez, Cesar, Huh, Winston W., Naing, Aung, Tsimberidou, Apostolia Maria, Wheler, Jennifer J., Piha-Paul, Sarina Anne, Janku, Filip, Kleinerman, Eugenie, Kurzrock, Razelle

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Clinical characteristics and outcomes of pediatric oncology patients with aggressive biology enrolled in phase I clinical trials designed for adults: the university of Texas MD and... von Corrales-Medina, Fernando F, Herzog, Cynthia, Hess, Kenneth, Egas-Bejar, Daniela, Hong, David S, Falchook, Gerald, Anderson, Pete, Nunez, Cesar, Huh, Winston W, Naing, Aung, Tsimberidou, Apostolia M, Wheler, Jennifer, Paul, Sarina Piha, Janku, Filip, Kleinerman, Eugenie S, Kurzrock, Razelle, Subbiah, Vivek

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