Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides von Lennox, Kim A, Behlke, Mark A

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Evaluation and Reduction of CRISPR Off-Target Cleavage Events von Vakulskas, Christopher A., Behlke, Mark A.

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Identification of preexisting adaptive immunity to Cas9 proteins in humans von Charlesworth, Carsten T., Deshpande, Priyanka S., Dever, Daniel P., Camarena, Joab, Lemgart, Viktor T., Cromer, M. Kyle, Vakulskas, Christopher A., Collingwood, Michael A., Zhang, Liyang, Bode, Nicole M., Behlke, Mark A., Dejene, Beruh, Cieniewicz, Brandon, Romano, Rosa, Lesch, Benjamin J., Gomez-Ospina, Natalia, Mantri, Sruthi, Pavel-Dinu, Mara, Weinberg, Kenneth I., Porteus, Matthew H.

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A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells von Vakulskas, Christopher A., Dever, Daniel P., Rettig, Garrett R., Turk, Rolf, Jacobi, Ashley M., Collingwood, Michael A., Bode, Nicole M., McNeill, Matthew S., Yan, Shuqi, Camarena, Joab, Lee, Ciaran M., Park, So Hyun, Wiebking, Volker, Bak, Rasmus O., Gomez-Ospina, Natalia, Pavel-Dinu, Mara, Sun, Wenchao, Bao, Gang, Porteus, Matthew H., Behlke, Mark A.

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CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy von Rosenblum, Daniel, Gutkin, Anna, Kedmi, Ranit, Ramishetti, Srinivas, Veiga, Nuphar, Jacobi, Ashley M., Schubert, Mollie S., Friedmann-Morvinski, Dinorah, Cohen, Zvi R., Behlke, Mark A., Lieberman, Judy, Peer, Dan

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Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins von Quadros, Rolen M, Miura, Hiromi, Harms, Donald W, Akatsuka, Hisako, Sato, Takehito, Aida, Tomomi, Redder, Ronald, Richardson, Guy P, Inagaki, Yutaka, Sakai, Daisuke, Buckley, Shannon M, Seshacharyulu, Parthasarathy, Batra, Surinder K, Behlke, Mark A, Zeiner, Sarah A, Jacobi, Ashley M, Izu, Yayoi, Thoreson, Wallace B, Urness, Lisa D, Mansour, Suzanne L, Ohtsuka, Masato, Gurumurthy, Channabasavaiah B

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A Direct Comparison of Anti-microRNA Oligonucleotide Potency von Lennox, Kim A., Behlke, Mark A.

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Engineered transfer RNAs for suppression of premature termination codons von Lueck, John D., Yoon, Jae Seok, Perales-Puchalt, Alfredo, Mackey, Adam L., Infield, Daniel T., Behlke, Mark A., Pope, Marshall R., Weiner, David B., Skach, William R., McCray, Paul B., Ahern, Christopher A.

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Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress von Michel, Carlos I., Holley, Christopher L., Scruggs, Benjamin S., Sidhu, Rohini, Brookheart, Rita T., Listenberger, Laura L., Behlke, Mark A., Ory, Daniel S., Schaffer, Jean E.

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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation von Gantier, Michael P., McCoy, Claire E., Rusinova, Irina, Saulep, Damien, Wang, Die, Xu, Dakang, Irving, Aaron T., Behlke, Mark A., Hertzog, Paul J., Mackay, Fabienne, Williams, Bryan R. G.

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Predicting Stability of DNA Duplexes in Solutions Containing Magnesium and Monovalent Cations von Owczarzy, Richard, Moreira, Bernardo G, You, Yong, Behlke, Mark A, Walder, Joseph A

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy von Rossi, John J, Kim, Dong-Ho, Behlke, Mark A, Rose, Scott D, Chang, Mi-Sook, Choi, Sangdun

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In vivo SELEX for Identification of Brain-penetrating Aptamers von Cheng, Congsheng, Chen, Yong Hong, Lennox, Kim A, Behlke, Mark A, Davidson, Beverly L

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Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection von Thiel, William H, Bair, Thomas, Peek, Andrew S, Liu, Xiuying, Dassie, Justin, Stockdale, Katie R, Behlke, Mark A, Miller, Jr, Francis J, Giangrande, Paloma H

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Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2′- O -methyl RNA molecular beacons von Zhao, Dan, Yang, Yantao, Qu, Na, Chen, Mingming, Ma, Zhao, Krueger, Christopher J, Behlke, Mark A, Chen, Antony K

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Sequence-dependent inhibition of cGAS and TLR9 DNA sensing by 2′-O-methyl gapmer oligonucleotides von Valentin, Roxane, Wong, Christophe, Alharbi, Arwaf S, Pradeloux, Solène, Morros, Makala P, Lennox, Kim A, Ellyard, Julia I, Garcin, Aurélie J, Ullah, Tomalika R, Kusuma, Gina D, Pépin, Geneviève, Li, Hong-Mei, Pearson, Jaclyn S, Ferrand, Jonathan, Lim, Rebecca, Veedu, Rakesh N, Morand, Eric F, Vinuesa, Carola G, Behlke, Mark A, Gantier, Michael P

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RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers von Dobosy, Joseph R, Rose, Scott D, Beltz, Kristin R, Rupp, Susan M, Powers, Kristy M, Behlke, Mark A, Walder, Joseph A

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Improved Performance of Anti-miRNA Oligonucleotides Using a Novel Non-Nucleotide Modifier von Lennox, Kim A, Owczarzy, Richard, Thomas, Derek M, Walder, Joseph A, Behlke, Mark A

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Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes von Kow, Rebecca L., Strovas, Timothy J., McMillan, Pamela J., Jacobi, Ashley M., Behlke, Mark A., Saxton, Aleen D., Latimer, Caitlin S., Keene, C. Dirk, Kraemer, Brian C.

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Pancreas-enriched miRNA refines endocrine cell differentiation von Kredo-Russo, Sharon, Mandelbaum, Amitai D, Ness, Avital, Alon, Ilana, Lennox, Kim A, Behlke, Mark A, Hornstein, Eran

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