Enhancing T‐cell responses to GCB‐like lymphomas with immune‐checkpoint‐blockade‐based therapies von Serganova, I., Bucktrout, R., Isshiki, Y., Sarapulov, A., Santella, A., Rodriguez, M., Chakraborty, S., Brunschvig, S., Qualls, D., Vardhana, S., Lesokhin, A., Melnick, A., Beguelin, W., Zappasodi, R.

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IL10 receptor is a novel therapeutic target in DLBCLs von Béguelin, W, Sawh, S, Chambwe, N, Chan, F C, Jiang, Y, Choo, J-W, Scott, D W, Chalmers, A, Geng, H, Tsikitas, L, Tam, W, Bhagat, G, Gascoyne, R D, Shaknovich, R

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Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance von Cordo Russo, R I, Béguelin, W, Díaz Flaqué, M C, Proietti, C J, Venturutti, L, Galigniana, N, Tkach, M, Guzmán, P, Roa, J C, O'Brien, N A, Charreau, E H, Schillaci, R, Elizalde, P V

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Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation von SALATINO, M, BEGUELIN, W, ELIZALDE, P. V, PETERS, M. G, CARNEVALE, R, PROIETTI, C. J, GALIGNIANA, M. D, VEDOY, C. G, SCHILLACI, R, CHARREAU, E. H, SOGAYAR, M. C

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EZH2 INHIBITION ENHANCES CAR T ANTITUMOR EFFECT BY INDUCING LYMPHOMA IMMUNOGENICITY AND ENHANCING T CELL FUNCTION von Isshiki, Y., Porazzi, P., Melnick, A., Ruella, M., Béguelin, W.

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Correction: Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance von Russo, R. I. Cordo, Béguelin, W., Flaqué, M. C. Díaz, Proietti, C. J., Venturutti, L., Galigniana, N., Tkach, M., Guzmán, P., Roa, J. C., O’Brien, N. A., Charreau, E. H., Schillaci, R., Elizalde, P. V.

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An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas von Venturutti, Leandro, Rivas, Martin A, Pelzer, Benedikt W, Flümann, Ruth, Hansen, Julia, Karagiannidis, Ioannis, Xia, Min, McNally, Dylan R, Isshiki, Yusuke, Lytle, Andrew, Teater, Matt, Chin, Christopher R, Meydan, Cem, Knittel, Gero, Ricker, Edd, Mason, Christopher E, Ye, Xiaofei, Pan-Hammarström, Qiang, Steidl, Christian, Scott, David W, Reinhardt, Hans Christian, Pernis, Alessandra B, Béguelin, Wendy, Melnick, Ari M

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Tumor necrosis factor transactivates ErbB2 in breast cancer cells von Rivas, MA, Tkach, M, Proietti, CJ, Rosemblit, C, Beguelin, W, Sundblad, V, Díaz Flaqué, MC, Charreau, EH, Elizalde, PV, Schillaci, R

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Abstract P5-03-02: Progestin Activation of p42/p44 MAPK Induces Stat3 Phosphorylation at Serine 727 Promoting Breast Cancer Growth von Tkach, M, Rosemblit, C, Béguelin, W, Proietti, C, Rivas, MA, Diaz Flaqué, MC, Cayrol, F, Charreau, EH, Elizalde, PV, Schillaci, R.

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Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition von Ennishi, Daisuke, Takata, Katsuyoshi, Béguelin, Wendy, Duns, Gerben, Mottok, Anja, Farinha, Pedro, Bashashati, Ali, Saberi, Saeed, Boyle, Merrill, Meissner, Barbara, Ben-Neriah, Susana, Woolcock, Bruce W, Telenius, Adèle, Lai, Daniel, Teater, Matt, Kridel, Robert, Savage, Kerry J, Sehn, Laurie H, Morin, Ryan D, Marra, Marco A, Shah, Sohrab P, Connors, Joseph M, Gascoyne, Randy D, Scott, David W, Melnick, Ari M, Steidl, Christian

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Major revision version 11.0 of the European AIDS Clinical Society Guidelines 2021 von Ryom, Lene, De Miguel, Rosa, Cotter, Aoife Grace, Podlekareva, Daria, Beguelin, Charles, Waalewijn, Hylke, Arribas, Josè R, Mallon, Patrick W. G., Marzolini, Catia, Kirk, Ole, Bamford, Alasdair, Rauch, Andri, Molina, Jean Michel, Kowalska, Justyna Dominika, Guaraldi, Giovanni, Winston, Alan, Boesecke, Christoph, Cinque, Paola, Welch, Steven, Collins, Simon, Behrens, Georg M. N.

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Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region von Bunting, Karen L., Soong, T. David, Singh, Rajat, Jiang, Yanwen, Béguelin, Wendy, Poloway, David W., Swed, Brandon L., Hatzi, Katerina, Reisacher, William, Teater, Matt, Elemento, Olivier, Melnick, Ari M.

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EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation von Béguelin, Wendy, Popovic, Relja, Teater, Matt, Jiang, Yanwen, Bunting, Karen L., Rosen, Monica, Shen, Hao, Yang, Shao Ning, Wang, Ling, Ezponda, Teresa, Martinez-Garcia, Eva, Zhang, Haikuo, Zheng, Yupeng, Verma, Sharad K., McCabe, Michael T., Ott, Heidi M., Van Aller, Glenn S., Kruger, Ryan G., Liu, Yan, McHugh, Charles F., Scott, David W., Chung, Young Rock, Kelleher, Neil, Shaknovich, Rita, Creasy, Caretha L., Gascoyne, Randy D., Wong, Kwok-Kin, Cerchietti, Leandro, Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Elemento, Olivier, Melnick, Ari M.

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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate von Venturutti, Leandro, Teater, Matt, Zhai, Andrew, Chadburn, Amy, Babiker, Leena, Kim, Daleum, Béguelin, Wendy, Lee, Tak C., Kim, Youngjun, Chin, Christopher R., Yewdell, William T., Raught, Brian, Phillip, Jude M., Jiang, Yanwen, Staudt, Louis M., Green, Michael R., Chaudhuri, Jayanta, Elemento, Olivier, Farinha, Pedro, Weng, Andrew P., Nissen, Michael D., Steidl, Christian, Morin, Ryan D., Scott, David W., Privé, Gilbert G., Melnick, Ari M.

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Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment von Li, Jie, Chin, Christopher R., Ying, Hsia-Yuan, Meydan, Cem, Teater, Matthew R., Xia, Min, Farinha, Pedro, Takata, Katsuyoshi, Chu, Chi-Shuen, Jiang, Yiyue, Eagles, Jenna, Passerini, Verena, Tang, Zhanyun, Rivas, Martin A., Weigert, Oliver, Pugh, Trevor J., Chadburn, Amy, Steidl, Christian, Scott, David W., Roeder, Robert G., Mason, Christopher E., Zappasodi, Roberta, Béguelin, Wendy, Melnick, Ari M.

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Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma von Takata, Katsuyoshi, Chong, Lauren C, Ennishi, Daisuke, Aoki, Tomohiro, Li, Michael Yu, Thakur, Avinash, Healy, Shannon, Viganò, Elena, Dao, Tao, Kwon, Daniel, Duns, Gerben, Nielsen, Julie S, Ben-Neriah, Susana, Tse, Ethan, Hung, Stacy S, Boyle, Merrill, Mun, Sung Soo, Bourne, Christopher M, Woolcock, Bruce, Telenius, Adèle, Kishida, Makoto, Rai, Shinya, Zhang, Allen W, Bashashati, Ali, Saberi, Saeed, D'Antonio, Gianluca, Nelson, Brad H, Shah, Sohrab P, Hoodless, Pamela A, Melnick, Ari M, Gascoyne, Randy D, Connors, Joseph M, Scheinberg, David A, Béguelin, Wendy, Scott, David W, Steidl, Christian

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An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities von Flümann, Ruth, Rehkämper, Tim, Nieper, Pascal, Pfeiffer, Pauline, Holzem, Alessandra, Klein, Sebastian, Bhatia, Sanil, Kochanek, Moritz, Kisis, Ilmars, Pelzer, Benedikt W, Ahlert, Heinz, Hauer, Julia, da Palma Guerreiro, Alexandra, Ryan, Jeremy A, Reimann, Maurice, Riabinska, Arina, Wiederstein, Janica, Krüger, Marcus, Deckert, Martina, Altmüller, Janine, Klatt, Andreas R, Frenzel, Lukas P, Pasqualucci, Laura, Béguelin, Wendy, Melnick, Ari M, Sander, Sandrine, Montesinos-Rongen, Manuel, Brunn, Anna, Lohneis, Philipp, Büttner, Reinhard, Kashkar, Hamid, Borkhardt, Arndt, Letai, Anthony, Persigehl, Thorsten, Peifer, Martin, Schmitt, Clemens A, Reinhardt, Hans Christian, Knittel, Gero

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Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture von Yusufova, Nevin, Kloetgen, Andreas, Teater, Matt, Osunsade, Adewola, Camarillo, Jeannie M., Chin, Christopher R., Doane, Ashley S., Venters, Bryan J., Portillo-Ledesma, Stephanie, Conway, Joseph, Phillip, Jude M., Elemento, Olivier, Scott, David W., Béguelin, Wendy, Licht, Jonathan D., Kelleher, Neil L., Staudt, Louis M., Skoultchi, Arthur I., Keogh, Michael-Christopher, Apostolou, Effie, Mason, Christopher E., Imielinski, Marcin, Schlick, Tamar, David, Yael, Tsirigos, Aristotelis, Allis, C. David, Soshnev, Alexey A., Cesarman, Ethel, Melnick, Ari M.

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The Tumor Associated Antigen PRAME Exhibits Dualistic Functions That Are Targetable in Diffuse Large B-Cell Lymphoma von Takata, Katsuyoshi, Chong, Lauren C., Ennishi, Daisuke, Thakur, Avinash, Healy, Shannon, Viganò, Elena, Dao, Tao, Nielsen, Julie S, Ben-Neriah, Susana, Aoki, Tomohiro, Tse, Ethan, Hung, Stacy, Li, Michael Y., Boyle, Merrill, Mun, Sung Soo, Bourne, Christopher, Woolcock, Bruce W, Telenius, Adele, Zhang, Allen, Bashashati, Ali, Saberi, Saeed, Antonio, Gianluca D', Nelson, Brad H, Shah, Sohrab P, Hoodless, Pamela, Melnick, Ari, Gascoyne, Randy D., Connors, Joseph M, Scheinberg, David A., Béguelin, Wendy, Scott, David W., Steidl, Christian

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Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma von Ennishi, Daisuke, Takata, Katsuyoshi, Béguelin, Wendy, Duns, Gerben, Mottok, Anja, Farinha, Pedro, Bashashati, Ali, Scott, David, Boyle, Merrill, Meissner, Barbara, Ben-Neriah, Susana, Woolcock, Bruce W, Telenius, Adele, Lai, Daniel, Teater, Matthew R, Kridel, Robert, Savage, Kerry J, Sehn, Laurie H, Morin, Ryan D., Marra, Marco A., Shah, Sohrab P, Connors, Joseph M., Gascoyne, Randy D., Scott, David W., Melnick, Ari M, Steidl, Christian

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