Palliative intent treatment for head and neck cancer: an analysis of practice and outcomes von Begbie, F D, Douglas, C M, Finlay, F, Montgomery, J

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Inflammation and white matter degeneration persist for years after a single traumatic brain injury von JOHNSON, Victoria E, STEWART, Janice E, BEGBIE, Finn D, TROJANOWSKI, John Q, SMITH, Douglas H, STEWART, William

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Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer von Sternberg, Cora N, Fizazi, Karim, Saad, Fred, Shore, Neal D, De Giorgi, Ugo, Penson, David F, Ferreira, Ubirajara, Efstathiou, Eleni, Madziarska, Katarzyna, Kolinsky, Michael P, Cubero, Daniel I. G, Noerby, Bettina, Zohren, Fabian, Lin, Xun, Modelska, Katharina, Sugg, Jennifer, Steinberg, Joyce, Hussain, Maha

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Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma von Choueiri, Toni K, Escudier, Bernard, Powles, Thomas, Mainwaring, Paul N, Rini, Brian I, Donskov, Frede, Hammers, Hans, Hutson, Thomas E, Lee, Jae-Lyun, Peltola, Katriina, Roth, Bruce J, Bjarnason, Georg A, Géczi, Lajos, Keam, Bhumsuk, Maroto, Pablo, Heng, Daniel Y.C, Schmidinger, Manuela, Kantoff, Philip W, Borgman-Hagey, Anne, Hessel, Colin, Scheffold, Christian, Schwab, Gisela M, Tannir, Nizar M, Motzer, Robert J

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Enzalutamide in Metastatic Prostate Cancer before Chemotherapy von Beer, Tomasz M, Armstrong, Andrew J, Rathkopf, Dana E, Loriot, Yohann, Sternberg, Cora N, Higano, Celestia S, Iversen, Peter, Bhattacharya, Suman, Carles, Joan, Chowdhury, Simon, Davis, Ian D, de Bono, Johann S, Evans, Christopher P, Fizazi, Karim, Joshua, Anthony M, Kim, Choung-Soo, Kimura, Go, Mainwaring, Paul, Mansbach, Harry, Miller, Kurt, Noonberg, Sarah B, Perabo, Frank, Phung, De, Saad, Fred, Scher, Howard I, Taplin, Mary-Ellen, Venner, Peter M, Tombal, Bertrand

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Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, control... von Eng, Cathy, Kim, Tae Won, Bendell, Johanna, Argilés, Guillem, Tebbutt, Niall C, Di Bartolomeo, Maria, Falcone, Alfredo, Fakih, Marwan, Kozloff, Mark, Segal, Neil H, Sobrero, Alberto, Yan, Yibing, Chang, Ilsung, Uyei, Anne, Roberts, Louise, Ciardiello, Fortunato, Ahn, JB, Asselah, J, Badarinath, S, Baijal, S, Begbie, S, Berry, S, Canon, JL, Carbone, RG, Cervantes, A, Cha, YJ, Chang, K, Chaudhry, A, Chmielowska, E, Cho, SH, Chu, D, Couture, F, Cultrera, J, Cunningham, D, Van Cutsem, E, Cuyle, PJ, Davies, J, Dowden, S, Dvorkin, M, Ganju, V, Garcia, RV, Kerr, R, Kim, TY, King, K, Kortmansky, J, Kozloff, M, Lam, KO, Lee, J, Lee, AS, Lesperance, B, Luppi, G, Ma, B, Maiello, E, Mandanas, R, Marshall, J, Marx, G, Mullamitha, S, Nechaeva, M, Park, JO, Pavlakis, N, Ponce, CG, Potemski, P, Raouf, S, Reeves, J, Segal, N, Siena, S, Smolin, A, Streb, JO, Strickland, A, Szutowicz-Zielinska, E, Tabernero, JM, Tan, B, Valera, JS, Van den Eynde, M, Vergauwe, P, Vickers, M, Womack, M, Wroblewska, M, Young, R

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Whole–genome characterization of chemoresistant ovarian cancer von Patch, Ann-Marie, Christie, Elizabeth L., Etemadmoghadam, Dariush, Garsed, Dale W., George, Joshy, Fereday, Sian, Nones, Katia, Cowin, Prue, Alsop, Kathryn, Bailey, Peter J., Kassahn, Karin S., Newell, Felicity, Quinn, Michael C. J., Kazakoff, Stephen, Quek, Kelly, Wilhelm-Benartzi, Charlotte, Curry, Ed, Leong, Huei San, Hamilton, Anne, Mileshkin, Linda, Au-Yeung, George, Kennedy, Catherine, Hung, Jillian, Chiew, Yoke-Eng, Harnett, Paul, Friedlander, Michael, Quinn, Michael, Pyman, Jan, Cordner, Stephen, O’Brien, Patricia, Leditschke, Jodie, Young, Greg, Strachan, Kate, Waring, Paul, Azar, Walid, Mitchell, Chris, Traficante, Nadia, Hendley, Joy, Thorne, Heather, Shackleton, Mark, Miller, David K., Arnau, Gisela Mir, Tothill, Richard W., Holloway, Timothy P., Semple, Timothy, Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Idrisoglu, Senel, Bruxner, Timothy J. C., Christ, Angelika N., Poudel, Barsha, Holmes, Oliver, Anderson, Matthew, Leonard, Conrad, Lonie, Andrew, Hall, Nathan, Wood, Scott, Taylor, Darrin F., Xu, Qinying, Fink, J. Lynn, Waddell, Nick, Drapkin, Ronny, Stronach, Euan, Gabra, Hani, Brown, Robert, Jewell, Andrea, Nagaraj, Shivashankar H., Markham, Emma, Wilson, Peter J., Ellul, Jason, McNally, Orla, Doyle, Maria A., Vedururu, Ravikiran, Stewart, Collin, Lengyel, Ernst, Pearson, John V., Waddell, Nicola, deFazio, Anna, Grimmond, Sean M., Bowtell, David D. L.

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Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma von Kondrashova, Olga, Topp, Monique, Nesic, Ksenija, Lieschke, Elizabeth, Ho, Gwo-Yaw, Harrell, Maria I., Zapparoli, Giada V., Hadley, Alison, Holian, Robert, Boehm, Emma, Heong, Valerie, Sanij, Elaine, Pearson, Richard B., Krais, John J., Johnson, Neil, McNally, Orla, Ananda, Sumitra, Alsop, Kathryn, Hutt, Karla J., Kaufmann, Scott H., Lin, Kevin K., Harding, Thomas C., Traficante, Nadia, deFazio, Anna, McNeish, Iain A., Bowtell, David D., Swisher, Elizabeth M., Dobrovic, Alexander, Wakefield, Matthew J., Scott, Clare L.

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Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy von Scher, Howard I, Fizazi, Karim, Saad, Fred, Taplin, Mary-Ellen, Sternberg, Cora N, Miller, Kurt, de Wit, Ronald, Mulders, Peter, Chi, Kim N, Shore, Neal D, Armstrong, Andrew J, Flaig, Thomas W, Fléchon, Aude, Mainwaring, Paul, Fleming, Mark, Hainsworth, John D, Hirmand, Mohammad, Selby, Bryan, Seely, Lynn, de Bono, Johann S

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Prognostic gene expression signature for high-grade serous ovarian cancer von Intermaggio, M.P., Leong, H.S., Chen, S., Elatre, W., Gilks, B., Volchek, M., Wang, C., Mackenzie, R., George, J., Bowtell, D., Chenevix-Trench, G., Green, A., Gertig, D., Fereday, S., Moore, S., Hung, J., Harrap, K., Malt, M., Robertson, R., Maidens, J., Jayde, V., Mamers, P., Schmidt, T., Ball, C., Bilic, Sanela, Stuart-Harris, R., Clingan, P., Glasgow, A., Shannon, J., Young, B., Robertson, G., Carter, J., Dalrymple, C., Russell, P., Links, M., Jaworski, R., Crandon, A., Horwood, K., Obermair, A., Wyld, D., Davy, M., Dodd, T., Healy, T., Pittman, K., Henderson, D., Pierdes, J., Brown, B., Hyde, S., Healy, D., McNealage, J., Simpson, I., Fox, S., Lade, S., Loughrey, M., Neesham, D., Bell, R., Ng, L.F., Whiteman, D., Fereday, S., Steed, H., Koziak, J.M., Goranova, T., Silva De Silva, D., Ramón y Cajal, T., García-Donas, J., Rodriguez, G.C., Harris, H.R., Greene, C.S., Zelaya, R.A., Sinn, P., Menkiszak, J., Pearce, C.L., Rhenius, V., Piskorz, A.M., Sharma, R., Johnatty, S.E., Larson, M.C., Luk, H., Hernandez, B.Y., Thompson, P.J., Sherman, M.E., Bodelon, C., Lewsley, L.A., Banerjee, S.N., Stronach, E.A., Haluska, P., Ray-Coquard, I., Winterhoff, B., Slamon, D., Levine, D.A., Menon, U., Goodman, M.T., Schildkraut, J.M., Brown, R., Berchuck, A., Chenevix-Trench, G., deFazio, A., Beeghly-Fadiel, A., Fasching, P.A., Orsulic, S.

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Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma von Flaherty, Keith T, Robert, Caroline, Hersey, Peter, Nathan, Paul, Garbe, Claus, Milhem, Mohammed, Demidov, Lev V, Hassel, Jessica C, Rutkowski, Piotr, Mohr, Peter, Dummer, Reinhard, Trefzer, Uwe, Larkin, James M.G, Utikal, Jochen, Dreno, Brigitte, Nyakas, Marta, Middleton, Mark R, Becker, Jürgen C, Casey, Michelle, Sherman, Laurie J, Wu, Frank S, Ouellet, Daniele, Martin, Anne-Marie, Patel, Kiran, Schadendorf, Dirk

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High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality von Devereaux, P.J, Lamy, Andre, Chan, Matthew T.V, Allard, René V, Lomivorotov, Vladimir V, Landoni, Giovanni, Zheng, Hong, Paparella, Domenico, McGillion, Michael H, Belley-Côté, Emilie P, Parlow, Joel L, Underwood, Malcolm J, Wang, Chew Yin, Dvirnik, Nazari, Abubakirov, Marat, Fominskiy, Evgeny, Choi, Stephen, Fremes, Stephen, Monaco, Fabrizio, Urrútia, Gerard, Maestre, Marialuz, Hajjar, Ludhmila A, Hillis, Graham S, Mills, Nicholas L, Margari, Vito, Mills, Joseph D, Billing, J. Stephen, Methangkool, Emily, Polanczyk, Carisi A, Sant’Anna, Roberto, Shukevich, Dmitry, Conen, David, Kavsak, Peter A, McQueen, Matthew J, Brady, Katheryn, Spence, Jessica, Le Manach, Yannick, Mian, Rajibul, Lee, Shun Fu, Bangdiwala, Shrikant I, Hussain, Sara, Borges, Flavia K, Pettit, Shirley, Vincent, Jessica, Guyatt, Gordon H, Yusuf, Salim, Alpert, Joseph S, White, Harvey D, Whitlock, Richard P

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Randomized phase 2 study of carboplatin and bevacizumab in recurrent glioblastoma von Field, Kathryn M, Simes, John, Nowak, Anna K, Cher, Lawrence, Wheeler, Helen, Hovey, Elizabeth J, Brown, Christopher S B, Barnes, Elizabeth H, Sawkins, Kate, Livingstone, Ann, Freilich, Ron, Phal, Pramit M, Fitt, Greg, Rosenthal, Mark A

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Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses von Cheasley, Dane, da Cunha Torres, Michelle, Salazar, Carolina, Xing, Zhongyue, Mes-Masson, Anne-Marie, Provencher, Diane M., Rahimi, Kurosh, Fasching, Peter A., Goodman, Marc T., Deen, Suha, Sieh, Weiva, Mateoiu, Constantina, Cook, Linda S., Le, Nhu D., Anglesio, Michael S., Chenevix-Trench, G., Traficante, N., Harrap, K., Sadkowsky, T., Mellon, A., Jones, M., Green, L., Ranieri, B., White, J., Bowes, L., Galletta, L., Giles, D., Hendley, J., Alsop, K., Young, C., Viduka, S., Glavinas, Lydia, Rutovitz, J., Glasgow, A., Bonaventura, T., Begbie, S., Baron-Hay, S., Nevell, D., Valmadre, S., Marsden, D., Beale, P., Beith, J., Carter, J., Dalrymple, C., Brand, A., Byth, K., Jaworski, R., Papadimos, D., Crandon, A., Cummings, M., Horwood, K., Perrin, L., Wyld, D., Davy, M., Oehler, M.K., Hall, C., Henderson, D., Miller, J., Blomfield, P., Rome, R., Grant, P., Laurie, R., Robbie, M., Manolitsas, T., McNealage, J., Susil, B., Sumithran, E., Phillips, K., Rischin, D., Fox, S., Loughrey, M., Billson, V., Neesham, D., Quinn, M., Blum, R., Leung, Y., Buck, M., Purdie, D., Ramus, Susan J., Scott, Clare L., Köbel, Martin, Gorringe, Kylie L., Allan, Prue E., Böhm, Maret, Christie, Michael, DeFazio, Anna, Fairweather, Nicole, Hadley, Alison M., Hendley, Joy, Ho, Gwo-Yaw, Huntsman, David G., Jobling, Tom W., Kennedy, Catherine J., Le Page, Cecile, Pyman, Jan, Rahimi, Kurosh, Samimi, Goli, Sharma, Ragwha, Antill, Yoland C., Gorringe, Kylie L.

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Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer von Shen, Hui, Fridley, Brooke L., Song, Honglin, Lawrenson, Kate, Cicek, Mine S., Tyrer, Jonathan, Zheng, Wei, Yang, Hannah P., Wozniak, Eva L., Ling Woo, Yin, Winterhoff, Boris, Wentzensen, Nicolas, Palmieri Weber, Rachel, Vitonis, Allison F., Vincent, Daniel, Vierkant, Robert A., Vergote, Ignace, Van Den Berg, David, Van Altena, Anne M., Thompson, Pamela J., Tessier, Daniel C., Terry, Kathryn L., Templeman, Claire, Siddiqui, Nadeem, Shu, Xiao-Ou, Severi, Gianluca, Schwaab, Ira, Salvesen, Helga B., Anne Rossing, Mary, Risch, Harvey A., Renner, Stefan P., Poole, Elizabeth M., Pike, Malcolm C., Phelan, Catherine M., Pelttari, Liisa M., Pejovic, Tanja, Ness, Roberta B., Moysich, Kirsten B., Monteiro, Alvaro N.A., Menon, Usha, Matsuo, Keitaro, Mat Adenan, Noor Azmi, Massuger, Leon F.A.G, Lurie, Galina, Lundvall, Lene, Lubiński, Jan, Lissowska, Jolanta, Levine, Douglas A., Lambrechts, Diether, Kupryjanczyk, Jolanta, Kiemeney, Lambertus A., Karlan, Beth Y., Karevan, Rod, Kalli, Kimberly R., Ji, Bu-Tian, Jakubowska, Anna, Iversen, Edwin, Høgdall, Claus K., Hoatlin, Maureen, Hillemanns, Peter, Halle, Mari K., Hall, Per, Gronwald, Jacek, Gore, Martin, Giles, Graham G., Gentry-Maharaj, Aleksandra, Fasching, Peter A., Ekici, Arif B., Edwards, Robert, Eccles, Diana, Easton, Douglas F., Doherty, Jennifer A., Despierre, Evelyn, Dansonka-Mieszkowska, Agnieszka, Cybulski, Cezary, Cramer, Daniel W., Cook, Linda S., Chen, Xiaoqing, Charbonneau, Bridget, Campbell, Ian, Butzow, Ralf, Bunker, Clareann H., Brueggmann, Doerthe, Brown, Robert, Brooks-Wilson, Angela, Brinton, Louise A., Bogdanova, Natalia, Block, Matthew S., Benjamin, Elizabeth, Beesley, Jonathan, Beckmann, Matthias W., Bandera, Elisa V., Baglietto, Laura, Armasu, Sebastian M., Liang, Dong, Lu, Karen, Hildebrandt, Michelle A.T., Sellers, Thomas A., Laird, Peter W., Leigh Pearce, Celeste

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ABCA transporter gene expression and poor outcome in epithelial ovarian cancer von Hedditch, Ellen L, Gao, Bo, Russell, Amanda J, Lu, Yi, Emmanuel, Catherine, Beesley, Jonathan, Johnatty, Sharon E, Chen, Xiaoqing, Harnett, Paul, George, Joshy, Williams, Rebekka T, Flemming, Claudia, Lambrechts, Diether, Despierre, Evelyn, Lambrechts, Sandrina, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter, Beckmann, Matthias W, Ekici, Arif B, Hein, Alexander, Matsuo, Keitaro, Hosono, Satoyo, Nakanishi, Toru, Yatabe, Yasushi, Pejovic, Tanja, Bean, Yukie, Heitz, Florian, Harter, Philipp, du Bois, Andreas, Schwaab, Ira, Hogdall, Estrid, Kjaer, Susan K, Jensen, Allan, Hogdall, Claus, Lundvall, Lene, Engelholm, Svend Aage, Brown, Bob, Flanagan, James, Metcalf, Michelle D, Siddiqui, Nadeem, Sellers, Thomas, Fridley, Brooke, Cunningham, Julie, Schildkraut, Joellen, Iversen, Ed, Weber, Rachel P, Berchuck, Andrew, Goode, Ellen, Bowtell, David D, Chenevix-Trench, Georgia, deFazio, Anna, Norris, Murray D, MacGregor, Stuart, Haber, Michelle, Henderson, Michelle J

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Small-scale mutations are infrequent as mechanisms of resistance in post-PARP inhibitor tumour samples in high grade serous ovarian cancer von Burdett, Nikki L., Willis, Madelynne O., Pandey, Ahwan, Fereday, Sian, DeFazio, Anna, Bowtell, David D. L., Christie, Elizabeth L.

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Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers von Helland, Åslaug, Anglesio, Michael S, George, Joshy, Cowin, Prue A, Johnstone, Cameron N, House, Colin M, Sheppard, Karen E, Etemadmoghadam, Dariush, Melnyk, Nataliya, Rustgi, Anil K, Phillips, Wayne A, Johnsen, Hilde, Holm, Ruth, Kristensen, Gunnar B, Birrer, Michael J, Pearson, Richard B, Børresen-Dale, Anne-Lise, Huntsman, David G, deFazio, Anna, Creighton, Chad J, Smyth, Gordon K, Bowtell, David D L

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380P Tumour naïve circulating tumour DNA (ctDNA) analysis in patients (pts) with resected colorectal cancer (CRC) in the phase III ASCOLT trial von Day, D., Starus, A., Lamik, A., Sieber, O., Begbie, S., Bonaventura, A., Rai, S., Karanth, N., Underhill, C.R., Nott, L.M., van Hazel, G., van Hagen, T., Wong, M., Saqib, A., Eastgate, M., Srivastav, R., Chia, J., Toh, H.C., Jones, F., Segelov, E.

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BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance von Nesic, Ksenija, Krais, John J, Wang, Yifan, Vandenberg, Cassandra J, Patel, Pooja, Cai, Kathy Q, Kwan, Tanya, Lieschke, Elizabeth, Ho, Gwo-Yaw, Barker, Holly E, Bedo, Justin, Casadei, Silvia, Farrell, Andrew, Radke, Marc, Shield-Artin, Kristy, Penington, Jocelyn S, Geissler, Franziska, Kyran, Elizabeth, Betsch, Robert, Xu, Lijun, Zhang, Fan, Dobrovic, Alexander, Olesen, Inger, Kristeleit, Rebecca, Oza, Amit, McNeish, Iain, Ratnayake, Gayanie, Traficante, Nadia, DeFazio, Anna, Bowtell, David D L, Harding, Thomas C, Lin, Kevin, Swisher, Elizabeth M, Kondrashova, Olga, Scott, Clare L, Johnson, Neil, Wakefield, Matthew J

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